Results 221 to 230 of about 928,232 (390)

5’‐Methylthioadenosine Metabolic Reprogramming Drives H3K79 Monomethylation‐Mediated PAK2 Upregulation to Promote Cadmium‐Induced Breast Cancer Progression by Impairing Autophagic Flux

Advanced Science, EarlyView.
Cadmium, a carcinogenic heavy metal, drives breast cancer progression via metabolic reprogramming and autophagic flux disruption. Multi‐omics revealed cadmium‐induced 5'‐methylthioadenosine depletion activates DOT1L‐mediated H3K79me1 at PAK2 promoter, upregulating PAK2 to block autophagy and driving malignancy. Clinically, 5'‐methylthioadenosine levels
Jingdian Li, Ping Deng, Tengfei Fan, Yuchen Qu, Miduo Tan, Yidan Liang, Peng Gao, Yongchun Peng, Mingke Qin, Sheng Jie, Rongrong Hao, Liting Wang, Lei Zhang, Chunhai Chen, Mindi He, Qinlong Ma, Yan Luo, Li Tian, Jia Xie, Mengyan Chen, Rui Tian, Min Li, Zhengping Yu, Zhou Zhou, Huifeng Pi   +24 more
wiley   +1 more source

Sclerosing Stromal Tumor: A Rare Ovarian Neoplasm [PDF]

, 2017
Shilpa Bairwa, Rahul Satarkar, Shivani Kalhan, Shilpa Garg, Ashok Sangwaiya, Pawan Singh   +5 more
openalex   +1 more source

NAC1/ACOX2 Axis as a Novel Therapeutic Target for Endometriosis-Related Ovarian Neoplasms. [PDF]

Int J Mol Sci
Sonia SB, Nakayama K, Razia S, Nakayama N, Ishikawa M, Yamashita H, Kanno K, Takeshita H, Zahan UF, Sohel HI, Kyo S.   +10 more
europepmc   +1 more source

Dysfunctional Decidual CD4+T Cells Induce Recurrent Pregnancy Loss via Palmitoylation‐Dependent Tim‐3 Lysosomal Sorting and Degradation

Advanced Science, EarlyView.
Dysfunctional decidual CD4+T cells induce recurrent pregnancy loss via palmitoylation‐dependent Tim‐3 lysosomal sorting and degradation. The integrated bioinformatics, proteomic, functional and model studies elucidate that Tim‐3 is palmitoylated by ZDHHC3 at Cys9. Sortilin bound to and directed palmitoylated Tim‐3 toward lysosome degradation, resulting
Liyuan Cui, Xinhang Meng, Yujie Luo, Jinfeng Qian, Fengrun Sun, Mingke Qiu, Songcun Wang   +6 more
wiley   +1 more source

Relationship between p53-associated proteins and estrogen receptor status in ovarian serous neoplasms

, 2006
E. Y. Cho, Yoon‐La Choi, Seoung Wan Chae, Jin Hee Sohn, Geunghwan Ahn   +4 more
openalex   +1 more source

Characteristics and Outcomes of Children and Adolescents With Epithelial Ovarian Neoplasms From a Tertiary Cancer Centre in Western India: A Retrospective Study. [PDF]

Cureus
Trivedi M, Meena P, Tak H, Dave D, Chandra M, Joshi N, Panchal HP, Gandhi J.   +7 more
europepmc   +1 more source

Advanced Microfluidics for Single Cell‐Based Cancer Research

Advanced Science, EarlyView.
Cutting‐edge microfluidic platforms are transforming single‐cell cancer research. This review highlights advanced technologies, from droplet microfluidics to tumour‐chips, that enable functional and spatial single‐cell analyses. By integrating biosensing, immune components, and patient‐derived materials, these systems offer new insights into tumour ...
Adriana Carneiro, Marta Aranda Palomer, Margarida Esteves, Carolina Rodrigues, José Maria Fernandes, Francisca Oliveira, Alexandra Teixeira, Carlos Honrado, Lorena Dieguez, Sara Abalde‐Cela, Miguel Xavier   +10 more
wiley   +1 more source

Ovarian metastases from gallbladder mimics primary ovarian neoplasm in young patient: a case report [PDF]

, 2018
Ting-Ying Lee, Chia‐Wen Wang, Teng-Wei Chen, De-Chuan Chan, Guo‐Shiou Liao, Hsiu‐Lung Fan   +5 more
openalex   +1 more source

Establishment of a Novel In Vitro and In Vivo Model to Understand Molecular Carcinogenesis of Endometriosis-Related Ovarian Neoplasms. [PDF]

Int J Mol Sci
Sohel HI, Kiyono T, Zahan UF, Razia S, Ishikawa M, Yamashita H, Kanno K, Sonia SB, Nakayama K, Kyo S.   +9 more
europepmc   +1 more source

Citrullination of AKT2 Catalyzed by PAD1 Facilitates the Maintenance of Stemness Characteristics of Ovarian Cancer Stem‐Like Cells in Ovarian Cancer

Advanced Science, EarlyView.
PAD1 is upregulated within the CD133+ subset or cisplatin‐resistant ovarian cancer cells, which is positively associated with the upregulation of stemness‐related markers and maintenance of stemness in OCSLCs. Mechanistically, PAD1‐catalyzed AKT2 citrullination at R202 facilitates AKT2 phosphorylation, promoting CEBPβ expression and its binding to the ...
Teng Xue, Xiaoqiu Liu, Chao Song, Shujia Fei, Jian Gu, Yun Han, Jia Xing, Xiaohan Liu, Fei Liang, Paul R Thompson, Xuesen Zhang   +10 more
wiley   +1 more source