Results 61 to 70 of about 186,551 (294)
Molecular Oncology, EarlyView.Screening 166 FDA‐approved anticancer drugs identifies the aromatase inhibitor Exemestane as a synergistic partner of PARP inhibitor Olaparib in BRCA‐proficient triple‐negative breast cancer. Exemestane induces ROS‐mediated replication stress, enhancing DNA damage and apoptosis alongside Olaparib.
Nur Aininie Yusoh +5 more
wiley +1 more source
Ovarian hydatid cyst mimicking an ovarian neoplasm [PDF]
Autopsy and Case Reports, 2020 Shangpliang, Darilin +4 more
openaire +5 more sources
Decrypting cancer's spatial code: from single cells to tissue niches
Molecular Oncology, EarlyView.Spatial transcriptomics maps gene activity across tissues, offering powerful insights into how cancer cells are organised, switch states and interact with their surroundings. This review outlines emerging computational, artificial intelligence (AI) and geospatial approaches to define cell states, uncover tumour niches and integrate spatial data with ...
Cenk Celik +4 more
wiley +1 more source
Practical guidance for applying the ADNEX model from the IOTA group to discriminate between different subtypes of adnexal tumors. [PDF]
, 2015 All gynecologists are faced with ovarian tumors on a regular basis, and the accurate preoperative diagnosis of these masses is important because appropriate management depends on the type of tumor. Recently, the International Ovarian Tumor Analysis (IOTA)
Anthoulakis, C +9 more
core +1 more source
miRegulome: a knowledge-base of miRNA regulomics and analysis [PDF]
, 2015 miRNAs regulate post transcriptional gene expression by targeting multiple mRNAs and hence can modulate multiple signalling pathways, biological processes, and patho-physiologies.
Azevedo, Vasco +13 more
core +3 more sources
Molecular Oncology, EarlyView.Loss‐of‐function mutations in the scaffold subunit of protein phosphatase 2A (PP2A), PPP2R1A, sensitize ovarian clear cell carcinoma to immune checkpoint blockade (ICB) by enhancing the interferon gamma response and promoting antitumor immune cell infiltration.
Matheus Henrique Dias, René Bernards
wiley +1 more source
Clinicoprognostical features of endometrial cancer patients with somatic mtDNA mutations [PDF]
, 2014 Somatic mitochondrial DNA (mtDNA) mutations have been found in a subset of endometrial cancers (EC) from different populations. We have investigated the relationship between mtDNA changes and clinical and pathological variables of women affected by ...
Bartnik, Ewa +6 more
core +1 more source
FEBS Open Bio, EarlyView.The tumor microenvironment is a dynamic, multifaceted complex system of interdependent cellular, biochemical, and biophysical components. Three‐dimensional in vitro models of the tumor microenvironment enable a better understanding of these interactions and their impact on cancer progression and therapeutic resistance.
Salma T. Rafik +3 more
wiley +1 more source
Predictive value of CA 125 and CA 72-4 in ovarian borderline tumors [PDF]
, 2009 Background: The aim of this study was to assess the prognostic value of cancer antigen (CA) 125 and CA 72-4 in patients with ovarian borderline tumor (BOT).
Burges, Alexander +8 more
core +1 more source
A Study of Histomorphology of Ovarian Neoplasms
Journal of Dhaka Medical College, 2018 Background: Ovarian malignancy is one of the most common causes of cancer deaths in females in Bangladesh. Due to poor early symptoms and lack of screening protocol, it is detected later in the clinical course of the disease. It is also one of the most treatable tumors because majorities are sensitive to chemo-radiation.
Shahana Khanam +4 more
openaire +2 more sources