Results 71 to 80 of about 65,548 (249)

Evaluating E-cadherin expression in ovarian surface epithelial tumors: A comprehensive analysis

Pakistan Journal of Pathology
Objective: To evaluate the frequency and pattern of E-cadherin immunoexpression in epithelial ovarian tumors (EOTs) and its association with histological subtypes and tumor grade. Material and Methods: This descriptive cross-sectional study was conducted in the Department of Pathology at Pakistan Institute of Medical Sciences.
Aisha Pervaiz, Armaghana Qamar Khan, Asma Khattak, Soffia Khursheed, Mehreen Mushtaq, Ramsh Ali   +5 more
openaire   +1 more source

Immunohistochemical Expression of Estrogen Receptor, Progesterone Receptor, Human Epidermal Growth Factor Receptor Type 2/neu, and S-100 in Epithelial Ovarian Tumors: Correlation with Clinicopathological Parameters

Journal of Applied Sciences and Clinical Practice
Background: Ovarian cancer is one of the most lethal gynecologic malignancies worldwide. More than 90% of ovarian cancers arise from the surface epithelium and are collectively termed epithelial ovarian tumors (EOTs).
Nasrin Parwin, Tripti Ashu, Jayashree Maity, Amit Kumar Ranjan   +3 more
doaj   +1 more source

Leveraging Microphysiological Systems to Facilitate Neutrophil‐Based Cancer Immunotherapy

Advanced Science, EarlyView.
Microphysiological systems are emerging as powerful human‐relevant platforms for studying neutrophil biology in cancer. Current applications of spheroids, organoids, and organ‐on‐a‐chip models are reviewed, together with future opportunities in behaviorome profiling, multi‐omics integration, personalized medicine, immune crosstalk, and multi‐organ ...
Shuai Shao, Markus Isfeld Diehl, Caroline N. Jones   +2 more
wiley   +1 more source

A study of ovarian tumors at Kathmandu medical college teaching hospital

Journal of Pathology of Nepal, 2017
Background: Ovarian cysts, which present as neoplastic and non-neoplastic lesions, are the most common gynecological cause of hospital admissions. This study was conducted to know the spectrum of ovarian tumors.Materials and methods: A cross sectional ...
Sailesh Bahadur Pradhan, Sanat Chalise, Binita Pradhan, Sailuja Maharjan   +3 more
doaj   +1 more source

Dual‐Target Nectin‐4/FAP Heterobivalent Probe 68Ga/177Lu‐FZ‐NF‐1 for Triple‐Negative Breast Cancer: Preclinical Theranostic Evaluation and First‐in‐Human Translation

Advanced Science, EarlyView.
A novel hetero‐bivalent agent, 68Ga/177Lu‐FZ‐NF‐1, concurrently targets Nectin‐4 and FAP in triple‐negative breast cancer. It yields significant preclinical tumor regression and clinically identifies additional metastatic lesions missed by 18F‐FDG PET, demonstrating promising theranostic potential for personalized management.
Ye Li, Li Sun, Xiaoyu Pan, Shuyi Lin, Dongliang Wang, Jianping Zhang, Fengshuang Qiu, Bin Zhu, Lingzhou Zhao, Fengsheng Zhang, Liyan Bai, Bingxin Gu, Xiaoping Xu, Shaoli Song   +13 more
wiley   +1 more source

Clinicopathological analysis of ovarian tumors in adolescent women under 20 years in Yazd, Iran (2011–2021): a 10-year retrospective study

Human Pathology Reports
Background: Ovarian tumors in women under 20 years of age present unique diagnostic and therapeutic challenges, owing to their diverse histological subtypes.
Saadat Eslami, Mohammad Aboutalebi Mirsaleh, Sedigheh Ekraminasab   +2 more
doaj   +1 more source

Primary Mucinous Adenocarcinoma of the Testis

Case Reports in Medicine, 2012
Ovarian-type surface epithelial neoplasms of the testis and paratestis are uncommon, and the mucinous subtype is particularly rare. These tumors represent a counterpart to ovarian cancer.
Takeshi Azuma, Yukihide Matayoshi, Yasushi Nagase   +2 more
doaj   +1 more source

Targeted Lysosomal Degradation of Extracellular and Membrane Proteins: From Receptor Hijacking to Programmable Endolysosomal Routing

Advanced Science, EarlyView.
Targeted chimeric degraders engage extracellular or membrane proteins and endocytosable cell‐surface receptors, forming ternary complexes that induce receptor‐mediated internalization. Following endocytosis, post‐endocytic sorting—not internalization alone—determines target fate.
Ke Liu, Xiyan Wang, Xiaozhen Liu, Chaoqi He, Da Qian, Xuli Meng, Liquan Zhu   +6 more
wiley   +1 more source

SOX30 Facilitates Triple‐Negative Breast Cancer Metastasis via TNFR2–NF‐κB Signaling and Tumor Microenvironment Remodeling

Advanced Science, EarlyView.
SOX30 drives triple‐negative breast cancer (TNBC) metastasis through a dual mechanism: direct activation of the TNFR2/NF‐κB signaling cascade and subsequent CCL20‐mediated recruitment of tumor‐associated macrophages (TAMs) into the tumor microenvironment.
Pingping Gao, Na Sun, Ning Yang, Tingting Zhao, Rui Fu, Zhenyu Wu, Yuqin Zhou, Xuanni Tan, Yi Zhang, Fei Han, Xiaowei Qi   +10 more
wiley   +1 more source

Biomimetic Scaffold‐Based 3D Models for Decoding Cancer Biology and Advancing Therapy

Advanced Science, EarlyView.
A timeline of the research history of 3D biomimetic scaffold materials and platforms. With advances in biomimetic materials and 3D scaffold technologies, their functional scope has expanded from mimicking basic physical and biochemical properties to increasingly replicating complex pathophysiological processes.
Haitao Zhao, Yuechen Han, Jie Li, Peng Luo, Lin Qi, Zhiwei Xia, Xiaosong Li, Quan Cheng, Chenshen Huang, Wantao Wu, Hao Zhang   +10 more
wiley   +1 more source