Results 1 to 10 of about 33,329 (197)

Comparative characteristic of lung cancer stem-like cells generated in vitro under different culture conditions [PDF]

open access: yesThe Ukrainian Biochemical Journal, 2021
Cancer stem cells (CSCs) play an important role in resistance to cancer treatment and recurrence developing. The aim of this study was to obtain cell culture of MOR line non-small cell lung cancer cells enriched in CSCs and to investigate its functional ...
O. V. Skachkova   +4 more
doaj   +1 more source

FEATURES OF EXPRESSION OF CD133 AND CD44 MARKERS OF TUMOR STEM CELLS WITH METASTATIC AND NON-METASTATIC GASTRIC CANCER

open access: yesСибирский онкологический журнал, 2021
Background. Gastric cancer is the second leading cause of cancer-related death due to advanced disease. A special role in the pathogenesis and metastasis of the tumor is assigned to tumor stem cells (TSC ),  responsible for resistance to chemotherapy and
A. B. Sagakyants   +10 more
doaj   +1 more source

Correlation of CD133 and SOX2 Expression with Regional Lymph Nodes Metastatic Status in Invasive Breast Carcinoma of No Special Type

open access: yesIndonesian Journal of Cancer, 2021
Background: CD133 overexpression can increase cell proliferation, migration, and epithelialmesenchymal transition that promotes metastasis. CD133 expression is induced by hypoxiainduced factor (HIF) which requires SOX2 binding in the promoter region ...
Sutrisno, Dyah Fauziah, Gondo Mastutik
doaj   +1 more source

Evaluation of CD133 and CD56/NCAM expression in Wilms tumor and their association with prognostic factors [PDF]

open access: yesIranian Journal of Basic Medical Sciences, 2020
Objective(s): To validate certain markers for cancer stem cell populations and their clinical importance in Wilms tumor (WT)Materials and Methods: Immunohistochemical study for CD133 and CD56/NCAM was performed on forty-six cases of WT that were ...
Amir Hossein Jafarian   +4 more
doaj   +1 more source

Equivalents of the neutrophil-to-lymphocyte ratio of circulating pool of stem and immature hematopoietic cells for assessing liver transplant status

open access: yesВестник трансплантологии и искусственных органов, 2023
Objective: to study the applicability of the neutrophil-to-lymphocyte ratio (NLR) for monitoring recipient status and for possible minimization of maintenance immunosuppression in the long-term period after liver transplantation (LT).Materials and ...
A. N. Shutko   +3 more
doaj   +1 more source

Phenotypic characteristics of CD133+EpCAM+ cancer stem-like cells derived from the human hepatoma HepG2 cell line

open access: yesJournal of the Arab Society for Medical Research, 2022
Background/aim Cancer stem-like cells (CSCs) have been found to be a serious hurdle in the effective treatment of cancer. The rationale of this study was to isolate and characterize CD133+EpCAM+-enriched cells from the human hepatoma HepG2 cell line to ...
Hadeer A. Aglan   +4 more
doaj   +1 more source

Circulating CD133+/–CD34– Have Increased c-MYC Expression in Myeloproliferative Neoplasms

open access: yesTurkish Journal of Hematology, 2023
Objective: Myeloproliferative neoplasms (MPNs) are hematopoietic stem cell (HSC)-originated diseases with clonal myeloproliferation. The constitutive activation of the JAK/STAT pathway is frequently detected in patients with Philadelphia chromosome ...
İldeniz Uslu Bıçak   +3 more
doaj   +1 more source

Drug resistance gene expression and chemotherapy sensitivity detection in Chinese women with different molecular subtypes of breast cancer

open access: yesCancer Biology & Medicine, 2020
Objective: The aim of the study was to identify specific chemosensitivity drugs for various molecular subtypes of breast tumors in Chinese women, by detecting the expression of drug resistance genes and by using the drug sensitivity test on different ...
Jing Zhao   +7 more
doaj   +1 more source

CD133 expression in patients with peripheral neuroblastic tumor: a systematic review [PDF]

open access: yesReviews in Clinical Medicine, 2015
Introduction: Neuroblastoma is known as one of the most common solid tumors in children, which is recently under the investigation for the expression of CD133, a marker of cancer stem cells.
Hedieh Nazarzadeh   +2 more
doaj   +1 more source

IMMUNOHISTOCHEMICAL STUDY OF PROTEINS PROX1, CD133 AND CD38 IN GLIOBLASTOMAS OF THE VENTRICULARSUBVENTRICULAR ZONE AND THEIR EFFECT ON THE LIFE EXPECTANCY OF PATIENTS

open access: yesУчёные записки Санкт-Петербургского государственного медицинского университета им. Акад. И.П. Павлова, 2020
Introduction. Glioblastoma (GBM) is one of the most malignant tumors. Currently, treatment options for GBM are limited, and patient survival rates over the past decades have not changed significantly.The objective of the study was a comparative study of ...
B. E. Galkovsky   +6 more
doaj   +1 more source

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