Results 21 to 30 of about 33,329 (197)

A pan-cancer perspective analysis reveals the opposite prognostic significance of CD133 in lower grade glioma and papillary renal cell carcinoma

Science Progress, 2021
CD133 is a valuable prognostic marker in multiple types of cancer. However, the expression, methylation levels, and prognostic relevance of CD133 have not been evaluated in a pan-cancer perspective.
Haiwei Wang, Xinrui Wang, Liangpu Xu, Ji Zhang, Hua Cao   +4 more
doaj   +1 more source

Evaluation of stemness genes expression of OCT4, SOX2, Nanog, C-Myc and surface marker of CD133 on myeloma cells [PDF]

Journal of Research in Applied and Basic Medical Sciences, 2020
Cancer stem cells that have the ability to proliferation and self-renewal were cause to drug resistance and metastasis in malignancies. In multiple myeloma, these cancer stem cells (MMCSCs) play a very important role in the recurrence of the disease ...
Ramin Saadatian kharajo, Saeid Abroun, Masoud Soleimani   +2 more
doaj  

Activated Carbon nanoparticles Loaded with Metformin for Effective Against Hepatocellular Cancer Stem Cells

International Journal of Nanomedicine, 2023
Lan Sun,1 Hong-Juan Yao,2 Jing-Cao Li,1 Bao-Quan Zhao,1 Yong-An Wang,1 Ying-Ge Zhang1 1Key Laboratory of Nanopharmacology and Nanotoxicology, Beijing Institute of Pharmacology and Toxicology, Beijing, People’s Republic of China; 2Key Laboratory of ...
Sun L, Yao HJ, Li JC, Zhao BQ, Wang YA, Zhang YG   +5 more
doaj  

CD133-directed CAR T cells for advanced metastasis malignancies: A phase I trial

OncoImmunology, 2018
Expressed by cancer stem cells of various epithelial cell origins, CD133 is an attractive therapeutic target for cancers. Autologous chimeric antigen receptor-modified T-cell directed CD133 (CART-133) was first tested in this trial.
Yao Wang, Meixia Chen, Zhiqiang Wu, Chuan Tong, Hanren Dai, Yelei Guo, Yang Liu, Jianhua Huang, Haiyan Lv, Can Luo, Kai-chao Feng, Qing-ming Yang, Xiao-lei Li, Weidong Han   +13 more
doaj   +1 more source

Hexokinase II in CD133+ and CD133- Hepatoma BEL-7402 Cells

Pathology & Oncology Research, 2011
Hexokinase II is a key enzyme in the glycolytic pathway and CD133+ human hepatoma cells possess cancer stem cell-like properties. The expression and enzyme activity of hexokinase II in CD133+ and CD133- hepatoma cells were examined. CD133 on the surface of the hepatoma BEL-7402 cells was analyzed by flow cytometry and the cells were magnetically sorted
Lei, Gong, Zhuqingqing, Cui, Xin, Yu, Yuhua, Wei, Jirun, Peng, Xisheng, Leng   +5 more
openaire   +2 more sources

Stem cells from glomerulus to distal tubule: a never-ending story?

Journal of Pediatric and Neonatal Individualized Medicine, 2016
The growing interest of research in the field of renal stem cells and kidney regeneration aims to get results that allow its clinical application, favoring the birth and development of regenerative medicine.
Melania Puddu, Claudia Fanni, Cristina Loddo, Vassilios Fanos   +3 more
doaj   +1 more source

Efficacy and biomarker analysis of CD133-directed CAR T cells in advanced hepatocellular carcinoma: a single-arm, open-label, phase II trial

OncoImmunology, 2020
Expressed by cancer stem cells of various epithelial cell origins and hepatocellular carcinoma (HCC), CD133 is an attractive therapeutic target for HCC. The marker CD133 is highly expressed in endothelial progenitor cells (EPC).
Hanren Dai, Chuan Tong, Daiwei Shi, Meixia Chen, Yelei Guo, Deyun Chen, Xiao Han, Hua Wang, Yao Wang, Pingping Shen   +9 more
doaj   +1 more source

Selective lentiviral gene delivery to CD133-expressing human glioblastoma stem cells. [PDF]

PLoS ONE, 2014
Glioblastoma multiforme (GBM) is a deadly primary brain malignancy. Glioblastoma stem cells (GSC), which have the ability to self-renew and differentiate into tumor lineages, are believed to cause tumor recurrence due to their resistance to current ...
N Sumru Bayin, Aram S Modrek, August Dietrich, Jonathan Lebowitz, Tobias Abel, Hae-Ri Song, Markus Schober, David Zagzag, Christian J Buchholz, Moses V Chao, Dimitris G Placantonakis   +10 more
doaj   +1 more source

Loss of α-1,2-mannosidase MAN1C1 promotes tumorigenesis of intrahepatic cholangiocarcinoma through enhancing CD133-FIP200 interaction

Cell Reports, 2023
Summary: CD133 is widely used as a marker to isolate tumor-initiating cells in many types of cancers. The structure of N-glycan on CD133 is altered during the differentiation of tumor-initiating cells.
Yuanyan Wei, Qihang Chen, Jiayue Chen, Chenhao Zhou, Shuting Geng, Danfang Shi, Sijing Huang, Zhiwei Liang, Xiaoning Chen, Ning Ren, Jianhai Jiang   +10 more
doaj   +1 more source

Generation of CD133+ cells from CD133− peripheral blood mononuclear cells and their properties [PDF]

Cardiovascular Research, 2006
CD133 may be the most specific marker of endothelial progenitor cells (EPCs), which are thought to be largely confined to the bone marrow milieu. This study reports on the phenotypic characterization and functional analysis of human CD133+ cells and their generation from cells in the peripheral circulation.Adult human CD133+ and CD133- cells were ...
Erik J, Suuronen, Serena, Wong, Varun, Kapila, Geeta, Waghray, Stewart C, Whitman, Thierry G, Mesana, Marc, Ruel   +6 more
openaire   +2 more sources