Results 131 to 140 of about 3,722,377 (405)

Next‐generation proteomics improves lung cancer risk prediction

Molecular Oncology, EarlyView.
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj, Clara Frick, Ben Schöttker, Bernd Holleczek, Hermann Brenner   +4 more
wiley   +1 more source

Ovarian cancer stem cells and targeted therapy

Journal of Ovarian Research, 2019
Background Ovarian cancer has the highest ratio of mortality among gynecologic malignancies. Chemotherapy is one of the most common treatment options for ovarian cancer.
Vahideh Keyvani, Moein Farshchian, Seyed-Alireza Esmaeili, Hadi Yari, Meysam Moghbeli, Seyed-Reza Kazemi Nezhad, Mohammad Reza Abbaszadegan   +6 more
doaj   +1 more source

Primary ovarian mucinous carcinoid tumor: A case report and review of literature

Taiwanese Journal of Obstetrics & Gynecology, 2019
Objective: Only a few cases of primary ovarian mucinous carcinoid tumor have been documented in the literature till date. We present a case of primary ovarian mucinous carcinoid tumor, atypical type, and review the reported cases.
Wen-Wei Hsu, Tsui-Lien Mao, Chi-Hau Chen
doaj   +1 more source

Figure S5 from Loss of MED12 Induces Tumor Dormancy in Human Epithelial Ovarian Cancer via Downregulation of EGFR [PDF]

, 2023
Xiaolin Luo, Chengcheng Deng, Xiaodong Su, Fang Wang, Zhen Chen, Xing-Ping Wu, Shaobo Liang, Jihong Liu, Liwu Fu   +8 more
openalex   +1 more source

Ovarian Cancer-Intrinsic Fatty Acid Synthase Prevents Anti-tumor Immunity by Disrupting Tumor-Infiltrating Dendritic Cells

Frontiers in Immunology, 2018
Fatty acid synthase (FASN), the key metabolic enzyme of de novo lipogenesis, provides proliferative and metastatic capacity directly to cancer cells have been described.
Li Jiang, Xuhong Fang, Hong Wang, Diyou Li, Xipeng Wang   +4 more
semanticscholar   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Role of the tumor microenvironment in chemotherapy resistance in ovarian cancer and targeted therapy

Journal of Ovarian Research
Ovarian cancer is currently the gynaecological malignancy with the highest mortality rate, with a five-year survival rate of less than 50%. Combination chemotherapy regimens primarily based on platinum remain the main treatment for advanced ovarian ...
Rui Qi, Jiapeng Yang, Shengjun Shen, Yue Yu, Qing Yang   +4 more
doaj   +1 more source

Human telomerase reverse transcriptase expression in ovarian tumors

Indian Journal of Pathology and Microbiology, 2012
Background : Ovarian cancer is the 6 th most common cancer among women. In ovarian tumors, the borderline category is not well defined due to the difficulty in assessing stromal invasion. The World Health Organization (WHO) defined it as tumor that lacks
Awadh Ali Makhashen Maraei, Ahmad Zailani Hatta, Mohd Sidik Shiran, Geok Chin Tan   +3 more
doaj   +1 more source

Practical guidance for applying the ADNEX model from the IOTA group to discriminate between different subtypes of adnexal tumors. [PDF]

, 2015
All gynecologists are faced with ovarian tumors on a regular basis, and the accurate preoperative diagnosis of these masses is important because appropriate management depends on the type of tumor. Recently, the International Ovarian Tumor Analysis (IOTA)
Anthoulakis, C, Bourne, T, Froyman, W, Kaijser, J, Landolfo, C, Timmerman, D, Van Calster, B, Van Hoorde, K, Vergote, I, Wynants, L   +9 more
core   +1 more source

The Tumor Microenvironment of Epithelial Ovarian Cancer and Its Influence on Response to Immunotherapy

Cancers, 2018
Immunotherapy as a treatment for cancer is a growing field of endeavor but reports of success have been limited for epithelial ovarian cancer. Overcoming the challenges to developing more effective therapeutic approaches lies in a better understanding of
G. Rodriguez, Kristianne J C Galpin, Curtis W. McCloskey, B. Vanderhyden   +3 more
semanticscholar   +1 more source