Results 151 to 160 of about 10,759 (216)
Angewandte Chemie, EarlyView.This review highlights an emerging anticancer approach integrating platinum agents into photodynamic therapy (PDT) and photoactivated chemotherapy (PACT) systems, further augmented by cancer cell membrane‐ and organelle‐targeting. By directing photoactivated platinum complexes from nontargeted distribution to cancer cells or defined subcellular sites ...
Shu Chen +3 more
wiley +2 more sources
Plant Virus Immunotherapy for HPV‐Associated Oropharyngeal Squamous Cell Carcinoma
Advanced NanoBiomed Research, EarlyView.Cowpea mosaic virus (CPMV) nanoparticles are safe and potent cancer immunotherapy candidates with strong immunomodulatory activity. CPMV activates innate immunity, which in turn drives adaptive immune responses and promotes durable, systemic antitumor effects.
Jessica Fernanda Affonso de Oliveira +7 more
wiley +1 more source
Advanced NanoBiomed Research, EarlyView.Bacterial membrane vesicles (BMVs) emerge as promising platforms for cancer immunotherapy owing to their intrinsic adjuvant properties and tunable cargo delivery capabilities. Their ability to modulate the tumor microenvironment, enhance antitumor immune responses, and support personalized therapeutic strategies highlights their growing potential as ...
Md Sifat Rahi +6 more
wiley +1 more source
Activation of Metal Complexes With Ultrasound Waves for Targeted Anticancer Therapy
Angewandte Chemie International Edition, EarlyView.Ultrasound enables non‐invasive activation of metal‐based therapeutics deep within tumors. Acoustic cavitation can drive sonodynamic reactive oxygen species generation or mechanochemical metal–ligand bond dissociation, enabling controlled release of bioactive payloads.
Félix Grosjean +3 more
wiley +1 more source
The Role of miRNAs in Chicken Immune Regulation and Prospects for Disease‐Resistant Breeding
Animal Research and One Health, EarlyView.A schematic workflow illustrating the screening of disease‐resistant miRNAs and the generation of miRNA‐based disease‐resistant chickens via PGC‐mediated germline genome editing. ABSTRACT MicroRNAs (miRNAs) are emerging as pivotal regulators of the immune system, playing a decisive role in shaping disease resistance in chicken.
Qiangzhou Wang +10 more
wiley +1 more source
How the HTAR will contribute to a value‐based decision‐making for medicinal products across the EU
British Journal of Clinical Pharmacology, EarlyView.The European Union Health Technology Regulation 2021/2282 (HTAR) introduces joint assessment of health technologies (including medicinal products and medical devices) across EU Member States. It was signed into law in 2021 and came into full force in January 2025.
Roisin Adams, Michal Stanak
wiley +1 more source
Efficacy, safety and cost‐effectiveness of CAR‐T therapy
British Journal of Clinical Pharmacology, EarlyView.CAR T‐cells demonstrate high efficacy in blood cancers, including ALL, MM and DLBCL. Innovations target solid tumours despite challenges such as antigen escape. Combination therapies enhance the delivery and infiltration of CAR T cells. Toxicity, cost and resistance remain major barriers to clinical use.
Emina Karahmet Sher +7 more
wiley +1 more source
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Obstetrical & Gynecological Survey, 1988
AbstractThirty‐eight women were operated for an ovarian tumor diagnosed during pregnancy, with an incidence of 1/2328 deliveries. The diameter of all tumors was above 5 cm. Of the 31 women operated before delivery, seven were untreated and 24 received supportive progestational therapy.
M, Ashkenazy +4 more
openaire +2 more sources
AbstractThirty‐eight women were operated for an ovarian tumor diagnosed during pregnancy, with an incidence of 1/2328 deliveries. The diameter of all tumors was above 5 cm. Of the 31 women operated before delivery, seven were untreated and 24 received supportive progestational therapy.
M, Ashkenazy +4 more
openaire +2 more sources
American Journal of Obstetrics and Gynecology, 1962
Abstract 1. 1. All previously reported cases of primary melanoma of the ovary are reviewed. 2. 2. A cystic ovarian teratoma is reported in which a pigmented component produced the predominant clinical and pathologic findings. In contrast to all other such neoplasms reported in the literature, this lesion is apparently benign. 3. 3.
J F, AFONSO +3 more
openaire +2 more sources
Abstract 1. 1. All previously reported cases of primary melanoma of the ovary are reviewed. 2. 2. A cystic ovarian teratoma is reported in which a pigmented component produced the predominant clinical and pathologic findings. In contrast to all other such neoplasms reported in the literature, this lesion is apparently benign. 3. 3.
J F, AFONSO +3 more
openaire +2 more sources
Acta Obstetricia et Gynecologica Scandinavica, 1984
Abstract. The results of 90 pregnancies complicated by an ovarian tumor are analysed. On this basis it seems advisable to follow a ‘wait‐and‐see’ policy until the 16th week. Tumors persisting into the second trimester can best be extirpated between the 16th and 20th week.
A P, Struyk, P E, Treffers
openaire +2 more sources
Abstract. The results of 90 pregnancies complicated by an ovarian tumor are analysed. On this basis it seems advisable to follow a ‘wait‐and‐see’ policy until the 16th week. Tumors persisting into the second trimester can best be extirpated between the 16th and 20th week.
A P, Struyk, P E, Treffers
openaire +2 more sources