Results 151 to 160 of about 45,008 (286)

Tumor and germline testing with next generation sequencing in epithelial ovarian cancer: a prospective paired comparison using an 18‐gene panel

open access: yesMolecular Oncology, Volume 20, Issue 3, Page 838-849, March 2026.
Genetic testing in epithelial ovarian cancer includes both germline and tumor‐testing. This approach often duplicates resources. The current prospective study assessed the feasibility of tumor‐first multigene testing by comparing tumor tissue with germline testing of peripheral blood using an 18‐gene NGS panel in 106 patients.
Elisabeth Spenard   +12 more
wiley   +1 more source

Acute E2/P4 loss compromises the biology and function of neurogenic niches during a vulnerable female aging period. [PDF]

open access: yesStem Cell Reports
Poorna Pillutla SV   +12 more
europepmc   +1 more source

Pearl‐Like Bioinspired Coating Enables Regulation of Mg Degradation for Osteoporotic Bone Repair

open access: yesAdvanced Science, Volume 13, Issue 13, 3 March 2026.
In this study, inspired by pearl architecture, we developed a layered Ca–P “brick” and Fn‐mimetic peptide “mortar” coating on Mg alloys. The Ca–P layer moderates corrosion and offers mineral cues, while the peptide enhances adhesion and regulates immune‐vascular responses.
Siming Zhang   +12 more
wiley   +1 more source

Loss of ovarian hormones is detrimental in early disease stages of mouse models of Alzheimer's disease and multi-etiology dementia. [PDF]

open access: yesBiol Sex Differ
Abi-Ghanem C   +15 more
europepmc   +1 more source

Early, But Not Late Onset Estrogen Replacement Therapy Prevents Oxidative Stress and Metabolic Alterations Caused by Ovariectomy

open access: yesAntioxidants and Redox Signaling, 2014
R. López-Grueso   +8 more
semanticscholar   +1 more source

CGRP Enhances the Regeneration of Bone Defects by Regulating Bone Marrow Mesenchymal Stem Cells Through Promoting ANGPTL4 Secretion by Bone Blood Vessels

open access: yesAdvanced Science, Volume 13, Issue 14, 9 March 2026.
CGRP interacts with HMEC‐1 by binding to surface receptors, influencing the downstream FAK/AKT/VEGF signaling pathway, and promoting the secretion of ANGPTL4 from vascular endothelial cells into the bone microenvironment. This, in turn, regulates the differentiation of BMSCs into osteoblasts, thus promoting bone formation. ABSTRACT Bone angiogenesis is
Qiong Lu   +9 more
wiley   +1 more source

Ovariectomy or Ovariohysterectomy?

open access: yesJournal of Feline Medicine and Surgery, 2011
openaire   +1 more source

Sex differences in neuromodulatory subcortical systems and their implications for Alzheimer's disease

open access: yesAlzheimer's &Dementia, Volume 22, Issue 3, March 2026.
Abstract Neuromodulatory subcortical systems (NSSs) are uniquely susceptible to dementia‐related pathology, leading to frequent molecular and behavioral impairments associated with altered function of these nuclei. Some of these systems display clear sex‐specific cytoarchitecture and signaling leading to distinct physiology and behavioral outputs in ...
Rosaria J. Rae   +53 more
wiley   +1 more source

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