Immunological Reviews, Volume 338, Issue 1, March 2026.ABSTRACT Sex plays a key role in shaping both anti‐cancer immunity and autoimmunity. Biological factors underlying sexual dimorphism have now been identified in multiple aspects of anti‐cancer immunity and autoimmunity. These factors include sex differences in hormone levels, chromosome complement, and expression of the long non‐coding RNA XIST.
Christian G. Bustillos +4 more
wiley +1 more source
Determination of appropriate time for establishing a model of postmenopausal osteoporosis induced by bilateral oophorectomy: From bibliometric analysis to animal experiment. [PDF]
PLoS OneShe Y +8 more
europepmc +1 more source
Sex Differences in Response to Viral Vector Vaccines—Implications for Future Vaccine Design
Immunological Reviews, Volume 338, Issue 1, March 2026.ABSTRACT Vaccination represents one of the most impactful public health achievements, preventing 3.5 to 5 million deaths annually according to estimates of the World Health Organization. Yet, recent outbreaks of emerging and reemerging infectious diseases highlight the need for rapid and strategic vaccine development using vaccine platforms ...
Ilka Grewe +2 more
wiley +1 more source
The effects of extracorporeal shockwave therapy on bone mineral density and microarchitecture in animal models of osteoporosis: a systematic review and meta-analysis. [PDF]
Front Rehabil SciWen X, Xiangli J, He Q, Yin Z.
europepmc +1 more source
Sex Differences in Lung Immunity
Immunological Reviews, Volume 338, Issue 1, March 2026.ABSTRACT Biological sex has a significant impact on how the immune system develops and responds to foreign and self‐antigens. Sex differences exist in innate and adaptive immune cells, both at homeostasis and in the context of infection and inflammatory diseases such as asthma, cancer, and autoimmune disorders.
Franz Puttur, Clare M. Lloyd
wiley +1 more source
Local Delivery of Genistein in Peri-Implant Defects Enhances Osseointegration in Ovariectomized Rats. [PDF]
Calcif Tissue IntDuarte ND +9 more
europepmc +1 more source
The X Factor in Immunity: Sex Differences Shaped by the X Chromosome
Immunological Reviews, Volume 338, Issue 1, March 2026.ABSTRACT There are sex differences with immune responses where females exhibit stronger immune responses compared to males. Both sex hormones and sex chromosome differences between males and females contribute to the observed sex differences with innate and adaptive immune cell composition and function.
Katherine B. Radovanovic +2 more
wiley +1 more source
Age-dependent neuroinflammation response to voluntary wheel running and Metformin treatment in the frontal cortex of ovariectomized female mice. [PDF]
Sci RepGrabowska K +6 more
europepmc +1 more source
How Does Biological Sex Impact Mucosal Bacterial Infection? Mucosal Defenses and Bacterial Detection
Immunological Reviews, Volume 338, Issue 1, March 2026.ABSTRACT Urinary tract infections possess substantial sex disparities in the incidence, immune response, and progression of infection. Some of these distinctions may be due to sexual dimorphism in mucosal barriers or sex differences in the initial immune response to infection.
Laura Ramirez Finn, Molly A. Ingersoll
wiley +1 more source
Quantifying the local strain energy density distribution in the mouse tibia: the critical role of the loading direction. [PDF]
Biomech Model MechanobiolFarage-O'Reilly SM +4 more
europepmc +1 more source