Results 21 to 30 of about 47,572 (286)
Frontiers in Aging Neuroscience, 2021 Background: Estrogen deficiency contributes to the development of Alzheimer’s disease (AD) in menopausal women. In the current study, we examined the impact of estrogen deficiency on mitochondrial function and cognition using a postmenopausal mouse model.
Wei Zhao +7 more
doaj +1 more source
A–C Estrogens as Potent and Selective Estrogen Receptor-Beta Agonists (SERBAs) to Enhance Memory Consolidation under Low-Estrogen Conditions [PDF]
, 2018 Estrogen receptor-beta (ERβ) is a drug target for memory consolidation in postmenopausal women. Herein is reported a series of potent and selective ERβ agonists (SERBAs) with in vivo efficacy that are A–C estrogens, lacking the B and D estrogen rings ...
Donaldson, William A. +12 more
core +4 more sources
Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Bābul, 2022 Background and Objective: Due to the physiological changes caused by estrogen deficiency in menopause and due to the importance of aerobic exercise as one of the non-pharmacological strategies to improve these changes, the present study was performed to ...
M Emamian Rostami, R Fathi, Kh Nasiri
doaj
Pistachio Extract Improves Neurocognitive Behaviors in Ovariectomized Mice [PDF]
Research Journal of Pharmacognosy, 2019 Background and objectives: Menopause is associated with depression as well as emotional and memory disorders. Based on the anti-inflammatory and antioxidant effects of pistachio, its effect on depression, cognitive function, anxiety and physical power in
Elham Hakimizadeh +6 more
doaj +1 more source
Menopause leads to elevated expression of macrophage-associated genes in the aging frontal cortex: rat and human studies identify strikingly similar changes. [PDF]
, 2012 BACKGROUND The intricate interactions between the immune, endocrine and central nervous systems shape the innate immune response of the brain. We have previously shown that estradiol suppresses expression of immune genes in the frontal cortex of ...
Carl Cotman +8 more
core +2 more sources
Vitamin K catabolite inhibition of ovariectomy-induced bone loss: Structure–activity relationship considerations [PDF]
, 2014 The potential benefit of vitamin K as a therapeutic in osteoporosis is controversial and the vitamin K regimen being used clinically (45 mg/day) employs doses that are many times higher than required to ensure maximal gamma‐carboxylation of the vitamin K‐
Emery, R +5 more
core +2 more sources
Majallah-i Dānishgāh-i ’Ulūm-i Pizishkī-i Shahīd Ṣadūqī Yazd, 2021 Introduction: During menopause, which is a part of the aging process in women, the level of sex hormones decreases, which causes problems such as memory impairment and cognitive functions.
Sajjad Sattai Mokhtari +7 more
doaj
PLoS ONE, 2022 Estrogens are thought to contribute to cognitive function in part by promoting the function of basal forebrain cholinergic neurons that project to the hippocampus and cortical regions including the entorhinal cortex.
Ariel A Batallán Burrowes +5 more
doaj +1 more source
SAGE Open Medicine, 2017 Objectives: Using ovariectomized rats, we examined the influence of combined exercise tolerance and natto intake on the bone loss inhibitory effect. Methods: We divided female Wistar rats into the following groups: Ovariectomy, Ovariectomy + Exercise ...
Michihiro Kawano +5 more
doaj +1 more source
Indian Journal of Animal Sciences, 2022 The present study was carried out to evaluate the biomarkers of oxidative stress and antioxidant activity in female dogs undergoing laparoscopic and open elective ovariectomy at Bihar Veterinary College, Patna in 2016-17.
Rajesh Kumar +4 more
doaj +1 more source