Results 41 to 50 of about 47,572 (286)

Sex‐Specific Regulation of Glycemic Homeostasis by Theabrownin from Pu‐erh Tea

Advanced Science, EarlyView.
Pu‐erh tea's key component, theabrownin (TB), lowers blood glucose in a sex‐specific manner. In females, estrogen boosts intestinal MUC2 production, which dramatically enhances TB's ability to inhibit the carbohydrate‐digesting enzyme α‐glucosidase.
Yang Li, Junliang Kuang, Dan Zheng, Jieyi Wang, Kun Ge, Chun Qu, Xiaojiao Zheng, Zhenxing Ren, Fengjie Huang, Mingliang Zhao, Yimin Sun, Huiheng Zhang, Keke Ding, Xixi Xia, Yajun Tang, Lu Liu, Jian Zhou, Fei Gao, Xiaohui Ma, Yongquan Xu, Guoxiang Xie, Aihua Zhao, Wei Jia   +22 more
wiley   +1 more source

Effects of remifemin treatment on bone integrity and remodeling in rats with ovariectomy-induced osteoporosis. [PDF]

PLoS ONE, 2013
This study aims to evaluate the effects of Remifemin (isopropanolic extract of Cimicifuga Racemosa) on postmenopausal osteoporosis. 120 female Sprague-Dawley rats were randomly assigned to four groups: sham surgery with vehicle, ovariectomy with vehicle,
Guangxia Cui, Huijie Leng, Ke Wang, Jianwei Wang, Sainan Zhu, Jing Jia, Xing Chen, Weiguang Zhang, Lihua Qin, Wenpei Bai   +9 more
doaj   +1 more source

Ovarian teratoma in the mare: a review and two cases [PDF]

, 2010
A 4-year-old Belgian Warmblood mare suffering from pelvic flexure impaction was diagnosed with a teratoma of the left ovary. The enlarged ovary was identified several days after treatment of the impaction.
de Kruif, Aart, De Schauwer, Catharina, Ducatelle, Richard, Durie, Inge, Govaere, Jan, Hoogewijs, Maarten, Martens, Ann, Schauvliege, Stijn, Smits, Katrien, Vanhaesebrouck, Emilie, Vercauteren, Griet   +10 more
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Intestinal perforation after surgical treatment for incisional hernia. iatrogenic or idiopathic? [PDF]

, 2018
Intestinal perforation (IP) is a life-threatening gastroenterological condition requiring urgent surgical care, which may present itself as an uncommon complication following incisional hernia repair surgery, most often because of iatrogenic traumatism ...
Amorosi, V, D'Angelo, F, Firmani, G, Longo, B, Santanelli di Pompeo, F, Sorotos, M   +5 more
core   +1 more source

ZMAT1 Promotes Osteoclastogenesis Through TRIM46 Mediated YAP1 Degradation and Inhibits Osteoblastogenesis

Advanced Science, EarlyView.
Zmat1 deficiency mitigates pathological bone loss by impairing osteoclastogenesis and promoting osteoblastogenesis. Mechanistically, in osteoclasts, Zmat1 loss relieves transcriptional repression of the E3 ligase TRIM46, promoting YAP1 degradation and inhibiting osteoclastogenic genes.
Xinyu Chang, Yijin Hou, Likun Cui, Huiqi Yu, Rong Liu, Junhao Sui, Zhong Zheng, Lu Liu, Jie Chen, Mengchen Chen, Chen Ding, Shuogui Xu, Sheng Xu, Hao Zhang   +13 more
wiley   +1 more source

Loss of testosterone impairs anti-tumor neutrophil function. [PDF]

, 2020
In men, the incidence of melanoma rises rapidly after age 50, and nearly two thirds of melanoma deaths are male. The immune system is known to play a key role in controlling the growth and spread of malignancies, but whether age- and sex-dependent ...
Arditi, Moshe, Crother, Timothy R, Lane, Malcolm E, Luu, Michael, Markman, Janet L, Martinon, Daisy, Noval Rivas, Magali, Porritt, Rebecca A, Posadas, Edwin M, Wakita, Daiko   +9 more
core   +1 more source

The Role of Extracellular Vesicles MicroRNAs in Sarcopenia: From Aging to Multi‐Morbidity

AGING MEDICINE, EarlyView.
Exosomes transporting miRNAs play a crucial bidirectional regulatory role in the process of sarcopenia, both in natural aging and under various pathological conditions. ABSTRACT Sarcopenia, defined as progressive loss of skeletal muscle mass and function, occurs during aging and has also been recognized for its detrimental effects in various disease ...
Bingyu Huang, Zhao Peng, Lin Kang
wiley   +1 more source

A preclinical mouse model mimicking the ovarian cancer‐induced estrogen deficiency‐depression axis

Animal Models and Experimental Medicine, EarlyView.
A preclinical mouse model of ovarian cancer–related depression was developed by combining intraperitoneal tumor cell injection, ovariectomy, and chronic restraint stress. The model replicates key clinical features including estrogen deficiency, depressive‐like behaviors, and tumor progression, and provides a reliable tool for studying the endocrine ...
Jiamin Liu, Yafei Yang, Chunxi Liu, Danting Wen, Tingyu Zhao, Ping Xie, Jing Xiao   +6 more
wiley   +1 more source

The effect of low-level estrogen in mandibular bone: An in vivo study

Dental Research Journal, 2019
Background: Low levels of estrogen can cause osteoporosis and usually occur during a woman's menopausal phase. Osteoporosis can lead to bone resorption, the absence of osseointegration, and implant failure.
Nike Hendrijanti, Rostiny Rostiny, Mefina Kuntjoro, Hanoem Eka Hidajati, Soekobagiono Soekobagiono, Adi Subianto, Maretaningtias Dwi Ariani, Dika Agung Bakhtiar   +7 more
doaj   +1 more source

EFEK EKSTRAK PAGAGAN (CENTELLA ASIATICA) TERHADAP EKSPRESI RESEPTOR ESTROGENβ,TGF β, HSP 70, KOLAGEN DAN PROLIFERASI EPITEL PADA DINDING VAGINA. Studi Eksperimental Pada Tikus Rattus Norvegicus Strain Strain Wistar yang Dilakukan Ov [PDF]

, 2010
Nyeri sanggama (dyspareunia) merupakan salah satu keluhan yang sering di jumpai pada perempuan menopause. Nyeri tersebut terjadi karena penurunan kolagen dan atrofi dinding vagina.
Raden, Akbar
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