Results 41 to 50 of about 45,008 (286)

Effect of Yakae-Prajamduen-Jamod Traditional Thai Remedy on Cognitive Impairment in an Ovariectomized Mouse Model and Its Mechanism of Action

Molecules, 2022
Cognitive impairment is a neurological symptom caused by reduced estrogen levels in menopausal women. The Thai traditional medicine, Yakae-Prajamduen-Jamod (YPJ), is a formula consisting of 23 medicinal herbs and has long been used to treat menopausal ...
Supawadee Daodee, Orawan Monthakantirat, Ariyawan Tantipongpiradet, Juthamart Maneenet, Yutthana Chotritthirong, Chantana Boonyarat, Charinya Khamphukdee, Pakakrong Kwankhao, Supaporn Pitiporn, Suresh Awale, Kinzo Matsumoto, Yaowared Chulikhit   +11 more
doaj   +1 more source

Similar and Additive Effects of Ovariectomy and Diabetes on Insulin Resistance and Lipid Metabolism

Biochemistry Research International, 2015
Type 2 diabetes mellitus (T2DM) is among the leading causes of death in postmenopausal women. The disruption of ovarian function may contribute to the incidence of T2DM.
Shady H. Tawfik, Bothaina F Mahmoud, M. Saad, Mona Shehata, M. Kamel, M. Helmy   +5 more
semanticscholar   +1 more source

IGF‐1 Deficiency Serves as an Integrated Biomarker Pathogenic Driver and Predictor in Poor Ovarian Response

Advanced Science, EarlyView.
IGF‐1 deficiency underlies poor ovarian response (POR), as reduced levels in follicular fluid and granulosa cells impair antral follicle formation and compromise reproductive outcomes. Including IGF‐1 as a biomarker significantly enhances the accuracy of models predicting both PORrisk and pregnancy success.
Zhu Hu, Yuanyuan Yu, Guanyou Huang, Jinnan Li, Chao Yang, Aizhuan Long, Jia Tang, Tengxiang Chen, Shuyun Zhao, Tuo Zhang   +9 more
wiley   +1 more source

The effect of low-level estrogen in mandibular bone: An in vivo study

Dental Research Journal, 2019
Background: Low levels of estrogen can cause osteoporosis and usually occur during a woman's menopausal phase. Osteoporosis can lead to bone resorption, the absence of osseointegration, and implant failure.
Nike Hendrijanti, Rostiny Rostiny, Mefina Kuntjoro, Hanoem Eka Hidajati, Soekobagiono Soekobagiono, Adi Subianto, Maretaningtias Dwi Ariani, Dika Agung Bakhtiar   +7 more
doaj   +1 more source

Augmentation of the Female Reproductive System Using Honey: A Mini Systematic Review

Molecules, 2021
Phytochemical contents of honey are presumed to be beneficial to the female reproductive system (FRS). However, the biological effects of honey supplementation (HS) in vivo on the FRS remain unclear. This review aims to investigate the current literature
Nur Hilwani Ismail, Siti Fatimah Ibrahim, Farah Hanan Fathihah Jaffar, Mohd Helmy Mokhtar, Kok Yong Chin, Khairul Osman   +5 more
doaj   +1 more source

ZMAT1 Promotes Osteoclastogenesis Through TRIM46 Mediated YAP1 Degradation and Inhibits Osteoblastogenesis

Advanced Science, EarlyView.
Zmat1 deficiency mitigates pathological bone loss by impairing osteoclastogenesis and promoting osteoblastogenesis. Mechanistically, in osteoclasts, Zmat1 loss relieves transcriptional repression of the E3 ligase TRIM46, promoting YAP1 degradation and inhibiting osteoclastogenic genes.
Xinyu Chang, Yijin Hou, Likun Cui, Huiqi Yu, Rong Liu, Junhao Sui, Zhong Zheng, Lu Liu, Jie Chen, Mengchen Chen, Chen Ding, Shuogui Xu, Sheng Xu, Hao Zhang   +13 more
wiley   +1 more source

Chronic Binge Alcohol and Ovarian Hormone Loss Dysregulate Circulating Immune Cell SIV Co-Receptor Expression and Mitochondrial Homeostasis in SIV-Infected Rhesus Macaques

Biomolecules, 2022
Effective antiretroviral therapy (ART) has transitioned HIV to a chronic disease, with more than 50% of people living with HIV (PLWH) being over the age of 50.
Patrick M. McTernan, Robert W. Siggins, Anna Catinis, Angela M. Amedee, Liz Simon, Patricia E. Molina   +5 more
doaj   +1 more source

THE INFLUENCE OF OVARIECTOMY ON THE SPONTANEOUS OCCURRENCE OF MAMMARY CARCINOMAS IN MICE

Journal of Experimental Medicine, 1927
1. Castration of female mice between 15 and 22 days of age entirely prevented the occurrence of spontaneous adenocarcinoma of the breast, while the non-breeding control mice of the same strain showed a tumor incidence of 78.5 per cent.
C. Cori
semanticscholar   +1 more source

A preclinical mouse model mimicking the ovarian cancer‐induced estrogen deficiency‐depression axis

Animal Models and Experimental Medicine, EarlyView.
A preclinical mouse model of ovarian cancer–related depression was developed by combining intraperitoneal tumor cell injection, ovariectomy, and chronic restraint stress. The model replicates key clinical features including estrogen deficiency, depressive‐like behaviors, and tumor progression, and provides a reliable tool for studying the endocrine ...
Jiamin Liu, Yafei Yang, Chunxi Liu, Danting Wen, Tingyu Zhao, Ping Xie, Jing Xiao   +6 more
wiley   +1 more source

The effects of Genistein on osseointegration of Titanium implants in experimental ovariectomized model

Revista Científica
Osseointegration is a challenge in the dental implant treatment of individuals with osteoporosis. Genistein is a phytoestrogen with beneficial effects in the prevention of osteoporosis.
Cansu Busra Uzun, Serkan Dundar, Mustafa Kom, Tuba Talo Yildirim, Alihan Bozoglan, Tansel Ansal Balci, Cemal Orhan, Kazim Sahin   +7 more
doaj   +1 more source