Results 31 to 40 of about 209,163 (316)

The Role of “Adult‐Onset” Cancer Predisposition Genes in Pediatric Cancer: A Comprehensive Review

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Current literature estimates that 10% of pediatric cancers are caused by pathogenic or likely pathogenic (P/LP) germline variants in cancer predisposition genes (CPGs). Variants in CPGs thought to increase cancer risk exclusively during adulthood are referred to as “adult‐onset” CPGs (aoCPGs).
Maria Rozo, Miriam A. Bornhorst, Angela J. Waanders, Sara Zarnegar‐Lumley, Ashwin Lakshman Koppayi, Lucy A. Godley   +5 more
wiley   +1 more source

Sociodemographic Factors Associated With Later Stage at Diagnosis of Pediatric Germ Cell Tumors: A Report From Children's Oncology Group Registries ACCRN07 and APEC14B1

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Germ cell tumors (GCTs) often arise in the ovaries and testes (extracranial) but can also develop in the brain (intracranial). We examined the relationship of individual, family, and community‐level socioeconomic status (SES) with stage of disease at diagnosis in a cohort of pediatric patients with GCT from Children's Oncology Group
Heydon K. Kaddas, Judy Y. Ou, Todd Alonzo, Logan G. Spector, Negar Fallahazad, Emily Owens, Anne C. Kirchhoff, Adam L. Green   +7 more
wiley   +1 more source

Gametogenesis and reproductive dynamics of Scinax acuminatus (Anura: Hylidae): morphological, histological and immunohistochemical analysis

Anais da Academia Brasileira de Ciências, 2021
To characterize the reproductive biology of Scinax acuminatus and contribute to the natural history of this species, the morphology of the reproductive system of males and females was analyzed at anatomical, histological and immunohistochemical levels ...
GABRIELA OLEA, ESTEBAN CHEIJ, ANA PAULA C. BOCCIONI, FLORENCIA RODRIGUEZ, JORGE CÉSPEDEZ, DANIEL LOMBARDO   +5 more
doaj   +1 more source

Ovarian Sex Cord Stromal Tumors in Children and Adolescents—The European Standard Clinical Practice Recommendations

Pediatric Blood &Cancer, EarlyView.
ABSTRACT As part of the European Cooperative Study Group for Paediatric Rare Tumours initiative, we developed standard clinical practice guidelines for ovarian sex cord stromal tumors, based on comprehensive national and international cohort analyses, literature review, and a final expert consensus conference.
Dominik T. Schneider, Kris‐Ann Schultz, Nora Schnitzler, Michael Abele, Tal Ben‐Ami, Ewa Bien, Gianni Bisogno, Ines B. Brecht, Maja Cesen, Andrea Ferrari, Michaela Kuhlen, Malgorzata A. Krawczyk, Ricardo Lopez‐Almaraz, Yves Reguerre, Calogero Virgone, Daniel Orbach   +15 more
wiley   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Study of Ovarian Damage in Piglets in an Experimental Model of Neonatal Asphyxia

Children
Background/Objectives: Perinatal asphyxia constitutes a major complication of the perinatal period with well-described effects on multiple organs and systems of the neonate; its impact, though, on the ovaries is hardly known. The objective of the present
Efstathia-Danai Bikouli, Rozeta Sokou, Monica Piras, Abraham Pouliakis, Eleftheria Karampela, Styliani Paliatsiou, Paraskevi Volaki, Gavino Faa, Theodoros Xanthos, Christos Salakos, Nicoletta M. Iacovidou   +10 more
doaj   +1 more source

Genome-Wide Identification of mRNAs, lncRNAs, and Proteins, and Their Relationship With Sheep Fecundity

Frontiers in Genetics, 2022
The exploration of multiple birth-related genes has always been a significant focus in sheep breeding. This study aimed to find more genes and proteins related to the litter size in sheep.
Chunxin Wang, Yunhui Zhao, ZhiYu Yuan, Yujin Wu, Zhuo Zhao, Cuiling Wu, Jian Hou, Mingxin Zhang   +7 more
doaj   +1 more source

Imaging of the Ovary [PDF]

Technology in Cancer Research & Treatment, 2004
Epithelial ovarian cancer has the highest mortality rate among the gynecologic cancers and spreads beyond the ovary in 90% of the women diagnosed with ovarian cancer. Detection before the disease has spread beyond the ovary would significantly improve the survival from ovarian cancer, which is currently only 30% over 5 years, despite extensive efforts ...
Molly A, Brewer, Urs, Utzinger, Jennifer K, Barton, James B, Hoying, Nathaniel D, Kirkpatrick, William R, Brands, John R, Davis, Katherine, Hunt, Sally J, Stevens, Arthur F, Gmitro   +9 more
openaire   +2 more sources

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source

Effects of Low and High Doses of Atrazine on the Structure of the Ovary of Adult Female Albino Rats [PDF]

Zagazig University Medical Journal
Background: Infertility has been increased due to continuous exposure to chemicals such as pesticides and herbicides in our life. Atrazine is one of the most common used herbicide worldwide.Aim: to show the toxic effect of atrazine on histological ...
Reham Abdel-Kareem, Mohey Hulail, Eman EL Sherbiny, Ola Abdelwahab   +3 more
doaj   +1 more source