Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
FEBS Letters, EarlyView.Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
Neonatal exposure to xenoestrogens impairs the ovarian response to gonadotropin treatment in lambs [PDF]
, 2015 Bisphenol A (BPA) and diethylstilbestrol (DES) are xenoestrogens which have been associated with altered effects on reproduction. We hypothesized that neonatal xenoestrogen exposure affects the ovarian functionality in lambs.
Belmonte, Norberto Miguel +8 more
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Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Some histological observations on the interstitial glands in she _camel ovary
Kufa Journal for Veterinary Medical Sciences, 2010 Histologically , the interstitial glands in she – camel ovary at one year aged was well- developed and scattered as cords among collage -nous fibers of the stroma in the ovary cortex .
Abdul- Hadi Sallal Mohammed
doaj +1 more source
Can the menopause really be reversed? [PDF]
, 2016 Scientists in Greece claimed recently to have “reversed the menopause”. They did this by injecting blood plasma that contains platelets into the ovaries of eight women who had not menstruated for around five months in order to stimulate ovarian ...
Sturmey, Roger
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Effect of Prey Density on Diurnal Activity and Ovarian Development in \u3ci\u3eCalosoma Calidum\u3c/i\u3e (Coleoptera: Carabidae): Implications for Biological Control of the Gypsy Moth, \u3ci\u3eLymantria Dispar (Lepidoptera: Lymantriidae)\u3c/i\u3e in the Midwest [PDF]
, 2017 Four feeding treatments were used in the laboratory to study the effects of the availability of prey on diurnal behavior and ovarian development of Calosoma calidum. Activity was closely monitored for six weeks.
Case, Laurie J, Jeffords, Michael R
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Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Clinical and structural changes in reproductive organs and endocrine glands of sterile cows [PDF]
Veterinary World, 2020 Aim: The study aimed to determine both macroscopic and microscopic changes in the reproductive organs of sterile cows. Materials and Methods: Careful clinical and gynecological examinations (using histological and histochemical methods) of organs of ...
Evgeny Skovorodin +4 more
doaj +1 more source
Reproductive biology of blue marlin (Makaira nigricans) in the western Pacific Ocean [PDF]
, 2009 The reproductive biology of blue marlin (Makaira nigricans) was assessed from 1001 fish (ranging from 121 to 275 cm in eye-to-fork length; EFL) caught by Taiwanese offshore longliners in the western Pacific Ocean from September 2000 to December ...
Chien-Chung Tszeng, Chien-Chung Tszeng +3 more
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