Results 61 to 70 of about 174,687 (312)
Molecular Oncology, EarlyView.Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim +3 more
wiley +1 more source
Primordial follicular assembly in humans : revisited [PDF]
, 2009 Peer ...
Maheshwari, A., Fowler, P. A.
core +1 more source
Polycystic ovaries and polycystic ovary syndrome
Gynecological Endocrinology, 1987 In the 50 years or so since the description by Irving F. Stein and Michael L. Leventhal of their finding of unexpectedly enlarged ovaries in a group of women with amenorrhea1, the syndrome we associate with their names has become widely recognized, variously interpreted and a subject of continual fascination for scores of reproductive scientists and ...
openaire +2 more sources
Molecular Oncology, EarlyView.The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington +10 more
wiley +1 more source
Revista Brasileira de Plantas Medicinais, 2012 Ginkgo biloba e Panax ginseng são plantas utilizadas na medicina tradicional. O objetivo do estudo foi avaliar a histologia gonadal de ratos machos e fêmeas Wistar submetidos aos tratamentos com o extrato de G. biloba (120 mg kg-1) ou P.
L.B. Kuntze +4 more
doaj +1 more source
HISTPATHOLOGICAL EFFECTS OF METHOTREXATE ON MALE AND FEMALE REPRODUCTIVE ORGANS IN WHITE MICE [PDF]
Basrah Journal of Veterinary Research, 2009 The present study was conducted on (40) white mice of approximately the same age (4-6 weeks) and body weight (23-25 gm) for the aim of observing the histopathological changes for male and female reproductive organs due to prolonged treatment (6 months ...
Khalil G. Chelab, Saleh K. Majeed
doaj +1 more source
Molecular Oncology, EarlyView.Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park +6 more
wiley +1 more source
Cancer‐associated mutations in endometriosis reframe a benign disease through molecular oncology
Molecular Oncology, EarlyView.This review aims to comprehensively analyse cancer‐associated somatic mutations (CAMs) present in endometriotic lesions, emphasizing their biological roles, spatial distribution and implications for translational applications in medicine. By contextualizing a benign state within a genomic framework, this analysis seeks to establish its value as a ...
Clarissa Mujacic +15 more
wiley +1 more source
Familial association of polycystic ovary syndrome (PCOS) in women attending the gynaecological endocrinology clinic at Groote Schuur Hospital [PDF]
, 2010 Includes bibliographical references (leaves 60-65).Polycystic ovary syndrome (PCOS) is the commonest endocrinopathy in women of reproductive age, affecting 5-10% of women in the general population.
Edelstein, Sascha
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The Iraqi Journal of Veterinary Medicine, 2000 The objective of the present investigation to study the effect of (HMG) which extracted from urine of menopausal women according to the method of Albert (1955).
J. K. Al-Ar, rak
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