Results 81 to 90 of about 162,204 (317)
Light microscope investigation of meiotic chromosome pairing in artificial triploid fishes with blocked ovaries [PDF]
, 1995 Chromosome pairing was light microscopically investigated by applying surface spreading technique in combination with 1-step silver staining method for the pachytene chromosome of artificial triploid transparent colored crucian carp (Carassius auratus ...
Giu Jianfang, Chen Li +3 more
core
Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
Neurofibroma of the ovary [PDF]
Gynecologic Oncology, 1990 We report an unusual example of ovarian neurofibroma in a woman with neurofibromatosis (von Recklinghausen's disease). The neoplasm caused ovarian enlargement which surgically simulated malignant neoplasm. Ovarian neurofibromas are extremely rare and may arise from small myelinated nerves in the ovarian hilum.
Hegg, Cynthia A., Flint, Andrew
openaire +3 more sources
Finding novel vulnerabilities of hypomorphic BRCA1 alleles
Molecular Oncology, EarlyView.Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder +10 more
wiley +1 more source
CYP genes over transcribed in steroidogenic ovaries and/or in steroidogenic MRTs compared to non steroidogenic ovaries. [PDF]
, 2013 Only CYP genes overexpressed in ovaries of blood-fed females at least in one time point and/or in MRTs compared to ovaries from NBF females are listed.
Emilie Guittard (492685) +7 more
core +1 more source
Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis
Molecular Oncology, EarlyView.This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht +3 more
wiley +1 more source
Relationship between polycystic ovaries, body mass index and insulin resistance [PDF]
, 2003 Background: to investigate insulin levels in lean and overweight women with and without polycystic ovaries. An observational, cross-sectional study at The Northem General Hospital, Sheffield, UK.Methods: sixty-eight women born at Jessop Hospital ...
Phillips, David +5 more
core +1 more source
Molecular Oncology, EarlyView.Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim +3 more
wiley +1 more source
Immunohistochemical detection of LepR in HOM and WT ovaries. [PDF]
, 2015 Panel A, B, C: LepR expression in HOM ovaries observed at 4×10 magnification, 10×10 magnification and, 20×10 magnification, respectively. Panel D, E, F: LepR expression in WT ovaries observed at 4×10 magnification, 10×10 magnification and 20×10 ...
Huijuan Shi (398246) +7 more
core +1 more source
Rangifer, 1992 A set of definitions for luteal structures and their regressing stages in red deer ovaries is suggested. Structural characteristics in ovaries pertaining to reproductive analysis is compiled from relevant literature and combined with observations from ...
Rolf Langvatn
doaj +1 more source