Results 81 to 90 of about 325,405 (336)

Ovarian growth and ovulation in the mature blue crab, Callinectes sapidus Rathbun [PDF]

open access: yes, 1942
Introduction. Observations: structure of the ovary during the periods of growth and ovulation in the mature crab (stages 1-5).
Hard, W.L.
core  

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

open access: yesMolecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz   +15 more
wiley   +1 more source

Exceptional longevity of mammalian ovarian and oocyte macromolecules throughout the reproductive lifespan

open access: yeseLife
The mechanisms contributing to age-related deterioration of the female reproductive system are complex, however aberrant protein homeostasis is a major contributor.
Ewa K Bomba-Warczak   +7 more
doaj   +1 more source

The spatiotemporal expression pattern of the bone morphogenetic protein family in rat ovary cell types during the estrous cycle. [PDF]

open access: yes, 2003
In the mammalian ovary, great interest in the expression and function of the bone morphogenetic protein (BMP) family has been recently generated from evidence of their critical role in determining folliculogenesis and female fertility.
Erickson, Gregory F, Shimasaki, Shunichi
core   +3 more sources

Effect of chemotherapy on passenger mutations in metastatic colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui   +6 more
wiley   +1 more source

Anatomical assessment of the development of testes and ovaries in red Sokoto goat (Capra hircus)

open access: yesNotulae Scientia Biologicae
The functional testis and ovary are essential for the continual existence of every species. The anatomical development of the testis and ovary in the fetuses of red Sokoto goats were evaluated in this study. A total of 40 apparently healthy pregnant red
Anietie Francis UDOUMOH   +2 more
doaj   +1 more source

The effect of high temperature on swine ovarian function in vitro

open access: yesVeterinární Medicína, 2010
The aim of the present study was to understand the hormonal mechanisms behind the effect of high temperatures on reproductive function. It was proposed that high temperatures can directly alter production of ovarian hormones and/or the response of ...
A.V. Sirotkin, M. Kacaniova
doaj   +1 more source

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

open access: yesMolecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués   +3 more
wiley   +1 more source

Lesions of the sheep reproductive system found in a slaughterhouse in the state of Bahia, Brazil [PDF]

open access: yesPesquisa Veterinária Brasileira
: The present study aimed to evaluate and diagnose pathologies of the reproductive system of slaughtered sheep in slaughterhouses in the state of Bahia since there are few data on the subject as well as it is important to note the diagnosis of these ...
Reanne M.M. Silva   +6 more
doaj   +2 more sources

Inflammation is a key contributor to ovarian cancer cell seeding. [PDF]

open access: yes, 2018
The incidence of ovarian cancer dramatically increases in early menopause but the factors contributing to cancer onset are unclear. Most ovarian cancers originate in the fallopian tube with subsequent implantation of malignant cells into the ovary ...
Jia, Dongyu   +3 more
core   +1 more source

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