Results 191 to 200 of about 691,736 (297)

Lactylation‐Driven YTHDC1 Alleviates MASLD by Suppressing PTPN22‐Mediated Dephosphorylation of NLRP3

Advanced Science, EarlyView.
In MASLD, YTHDC1 undergoes increased lactylation and ubiquitination, reducing its expression. AARS1 mediates lactylation at lysine 565, while disrupted binding to LDHA further promotes lactylation, suppressing YTHDC1. This downregulation enhances PTPN22 mRNA stability, leading to NLRP3 dephosphorylation and activation, which exacerbates inflammation ...
Feng Zhang, Linghua Zeng, Kunkun Zou, Keying Lin, Fangting Yao, Jinglun Song, Shumeng Zhang, Hanshu Feng, Zhichao Yang, Chunlei Wang, Hongtao Diao, Xue Kong, Tengfei Pan, Joonki Kim, Tianqi Duo, Linqiang Li, Yu Bian   +16 more
wiley   +1 more source

Bariatric surgery as a treatment of polycystic ovary syndrome: a systematic review and meta-analysis. [PDF]

Front Endocrinol (Lausanne)
Mirghani H, Shaman A.
europepmc   +1 more source

Barium Influx Mediated by the Cardiac Sodium-Calcium Exchanger in Transfected Chinese Hamster Ovary Cells [PDF]

, 1997
Madalina Condrescu, Galina Chernaya, Vijay G. Kalaria, John P. Reeves   +3 more
openalex   +1 more source

Is physical training important for women with polycystic ovary syndrome? [PDF]

, 2020
Victor Barbosa Ribeiro, Rafael Menezes-Reis, Gislaine Satyko Kogure, Arthur Zecchin, Higino Carlos Hahns Júnior   +4 more
openalex   +1 more source

Positive Feedback Loop of Histone Lactylation‐Driven HNRNPC Promotes Autophagy to Confer Pancreatic Ductal Adenocarcinoma Gemcitabine Resistance

Advanced Science, EarlyView.
Histone 3 lysine18 lactylation (H3K18la) drives heterogeneous nuclear ribonucleoprotein C (HNRNPC) overexpression, activating autophagy to mediate gemcitabine resistance by stabilizing TNF receptor‐associated factor 6 (TRAF6) mRNA. Concurrently, HNRNPC stabilizes aldehyde dehydrogenase 1 family member A3 (ALDH1A3) mRNA, which enhances glycolysis and ...
Xi‐Tai Huang, Jiao Chen, En‐Liang Zhu, Ming‐Jian Ma, Yang‐Yin‐Hui Yu, Ying‐Qin Zhu, Jing‐Yuan Ye, Jin‐Zhao Xie, Zi‐Yi Zhao, Xiao‐Yu Yin   +9 more
wiley   +1 more source

Key mitochondria-related genes and molecular mechanisms shared between polycystic ovary syndrome and atherosclerosis: A bioinformatics and machine learning study. [PDF]

Medicine (Baltimore)
Tang L, Long W, Chen Q, Chen J, Zhang Y, Nie Z, Li W.   +6 more
europepmc   +1 more source

Function of vitrified mouse ovaries tissue under static magnetic field after autotransplantation.

, 2017
Vida Sadat Kazemein Jasemi, F. Samadi, Hussein Eimani, Saeed Hasani, Rouhollah Fathi, Abdolhossein Shahverdi, Fatemeh Shahi Sadrabadi   +6 more
openalex   +1 more source

The Fruits of Conservatism in the Treatment of Ovarian Pathology [PDF]

, 1959
Christian, Howard J.
core   +1 more source

PARPi Combining Nanoparticle LIN28B siRNA for the Management of Malignant Ascites

Advanced Science, EarlyView.
This study demonstrates that co‐inhibition of LIN28B and PARP using siLin28b/DSSP@lip‐PEG‐FA nanoparticles in combination with the PARP inhibitor BMN673 effectively suppresses the accumulation of malignant ascites associated with advanced cancers.
Yan Fang, Qian Shen, Yao Lin, Jing Zhu, Xiaolan Zhu, Rui Huang, Yijia Wu, Feiyang Shen, Qian Li, Guopei Zheng, Zhe Zhang, Qian Chu, Junhao Hu, Jianfeng Shen   +13 more
wiley   +1 more source

Ipsilateral Fallopian Tube and Ovary Agenesis or Absence? Case Report and Review of the Literature [PDF]

, 2017
D Princi
openalex   +1 more source