Results 101 to 110 of about 334,324 (301)

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

Multivariate Time Series Model with Hierarchical Structure for Over‐Dispersed Discrete Outcomes

open access: yesJournal of Forecasting, 2012
ABSTRACTIn this paper, we propose a multivariate time series model for over‐dispersed discrete data to explore the market structure based on sales count dynamics. We first discuss the microstructure to show that over‐dispersion is inherent in the modeling of market structure based on sales count data.
Terui, Nobuhiko, Ban, Masataka
openaire   +1 more source

A probabilistic model for explaining the points achieved by a team in football competition. Forecasting and regression with applications to the Spanish competition [PDF]

open access: yes, 2019
In the last decades, a lot of research papers applying statistical methods for analysing sports data have been published. Football, also called soccer, is one of the most popular sports all over the world organised in national championships in a round ...
Dávila Cárdenes, Nancy   +2 more
core  

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Dispersion in a Gas Filled Hollow Core Photonic Crystal Fiber

open access: yesمجلة بغداد للعلوم, 2014
Hollow core photonic bandgap fibers provide a new geometry for the realization and enhancement of many nonlinear optical effects. Such fibers offer novel guidance and dispersion properties that provide an advantage over conventional fibers for various ...
Baghdad Science Journal
doaj   +1 more source

Statistical and Economic Evaluation of Time Series Models for Forecasting Arrivals at Call Centers

open access: yes, 2018
Call centers' managers are interested in obtaining accurate point and distributional forecasts of call arrivals in order to achieve an optimal balance between service quality and operating costs.
Bastianin, Andrea   +2 more
core   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Theoretical Re-evaluations of Scaling Relations between SMBHs and Their Host Galaxies–2. Importance of AGN Feedback Suggested by Stellar Age–Velocity Dispersion Relation

open access: yesFrontiers in Astronomy and Space Sciences, 2017
We present the galactic stellar age—velocity dispersion relation obtained from a semi-analytic model of galaxy formation. We divide galaxies into two populations: galaxies which have over-massive/under-massive black holes (BHs) against the best-fitting ...
Hikari Shirakata   +3 more
doaj   +1 more source

An assessment of failure to rescue derived from routine NHS data as a nursing sensitive patient safety indicator (report to Policy Research Programme)

open access: yes, 2010
Objectives: This study aims to assess the potential for deriving 2 mortality based failure to rescue indicators and a proxy measure, based on exceptionally long length of stay, from English hospital administrative data by exploring change in coding ...
Bottle, Alex   +2 more
core  

Iterated filtering methods for Markov process epidemic models

open access: yes, 2018
Dynamic epidemic models have proven valuable for public health decision makers as they provide useful insights into the understanding and prevention of infectious diseases. However, inference for these types of models can be difficult because the disease
Stocks, Theresa
core   +1 more source

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