Results 171 to 180 of about 810,349 (252)

Use of the Pharmacy First service in England in the first 12 months: geographic variation and health system context

Meng W, Sonnex K, Pehlivanli A, Allen T, Dolan E, Glover R, Goulding J, Higgins H, Mays N, Taylor A, Thornley T, Avery AJ.   +11 more
europepmc   +1 more source

Differential game in closed-loop supply chain of innovative products with double regrets of consumers. [PDF]

PLoS One
Ma Q, Peng Y, Liu Z.
europepmc   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Whole truth: resuscitating trauma patients with whole blood. [PDF]

Trauma Surg Acute Care Open
Gurney JM.
europepmc   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

From supply to strategy: leveraging central medical stores experiences and information for health system strengthening. [PDF]

J Pharm Policy Pract
Tarrafeta-Sayas MB, Rerat C, Pilon S, Rakotonarivo MV, Koukpemedji LD, Yapo S, Duncan R, Hodjo D, Baki LS, Minoungou A, Ravinetto R.   +10 more
europepmc   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Can cross-sector governance improve urban health resource supply? Evidence from China's Healthy City pilot policy. [PDF]

Front Public Health
Zheng J.
europepmc   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Adaptive laboratory evolution increased biofilm formation by <i>Sporomusa ovata</i> through a mutation in <i>galU</i>. [PDF]

Biofilm
Grøn LV, Muñoz-Duarte L, Marshall IPG, Johnsen NK, Eser BE, Ma Y, Eken M, Kofoed MVW, Koren K, Philips J.   +9 more
europepmc   +1 more source