Results 41 to 50 of about 30,197 (246)

Personalized Selumetinib Dosing in Pediatric Neurofibromatosis Type 1: Insights From a Pilot Therapeutic Drug Monitoring Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate selumetinib exposure using therapeutic drug monitoring (TDM) in pediatric patients with neurofibromatosis type 1 (NF1) and plexiform neurofibromas (PN), assess interpatient pharmacokinetic variability, and explore the relationship between drug exposure, clinical response, and adverse effects.
Janka Kovács, Zoltán Köllő, Balázs Gellért Karvaly, Mahmoud Obeidat, Rita Nagy, Péter Hegyi, Brigitta Teutsch, Eszter Tuboly, Miklós Garami   +8 more
wiley   +1 more source

Adherence to Protocol Recommendations for Children With Wilms Tumour in Two Consecutive Studies in the United Kingdom and Ireland—Does Variation Matter?

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background and Aims Wilms tumour (WT) has excellent event‐free and overall survival (OS). However, small differences exist between countries participating in the same international study. This led us to examine variation in adherence to protocol recommendations as a potential contributing factor.
Suzanne Tugnait, R. Al‐Saadi, A. Lopez‐Cortes, K. Dzhuma, M. Oostveen, J. Brok, S. Irtan, M. Weeks, J. Bate, S. Baker, R. Williams, M. Powis, D. Saunders, O. Olsen, T. Watson, S. Shelmerdine, S. Vaidya, L. Howell, C. Duncan, G. M. Vujanic, C. Stiller, G. P. Balchin, T. Chowdhury, K. Pritchard‐Jones   +23 more
wiley   +1 more source

Design of protection module of intrinsic safety power supply based on LT4356

Gong-kuang zidonghua, 2014
In view of problems of simple protection function, low conversion efficiency, poor anti-interference ability and low intrinsic safety current existed in current protection module of intrinsic safety power supply, a protection module of intrinsic safety ...
XIE Guojun, WANG Tongsheng, WANG Shufeng, ZHU Chengjia   +3 more
doaj   +1 more source

Numerical Simulation of Tail Over-Fire Air Supply of a Grate Biomass Boiler

Energies, 2022
By taking a 130 t/h water-cooled grate biomass boiler as the research object, the ANSYS software is applied to simulate the effects of the tail burnout air’s incidence angle, wind speed, and pipe diameter on flow field distribution in the furnace, the ...
Shidan Chi, Yan Liang, Weixi Chen, Zhen Hou, Tao Luan   +4 more
doaj   +1 more source

Sirolimus for Extracranial Arteriovenous Malformations: A Scoping Review of the Evidence in Syndromic and Non‐Syndromic Cases

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Arteriovenous malformations (AVMs) are rare, high‐flow, vascular anomalies that can occur either sporadically or as part of a genetic syndrome. AVMs can progress with serious morbidity and even mortality if left unchecked. Sirolimus is an mTOR inhibitor that is effective in low‐flow vascular malformations; however, its role in AVMs is unclear.
Will Swansson, Ingrid Winship, Gary Hammerschlag, Laura Scardamaglia   +3 more
wiley   +1 more source

Evaluating the Utility of Paired Tumor and Germline Targeted DNA Sequencing for Pediatric Oncology Patients: A Single Institution Report

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate the diagnostic yield and utility of universal paired tumor–normal multigene panel sequencing in newly diagnosed pediatric solid and central nervous system (CNS) tumor patients and to compare the detection of germline pathogenic/likely pathogenic variants (PV/LPVs) against established clinical referral criteria for cancer ...
Natalie Waligorski, Rebecca Ronsley, Shannon M. Stasi, Jeffrey Stevens, Erin R. Rudzinski, Christina M. Lockwood, Sarah E. S. Leary, Bonnie L. Cole, Michelle A. Ting, Vera Paulson   +9 more
wiley   +1 more source

THE IMPACT OF HUMAN RESOURCE MANAGEMENT PRACTICES OVER SUPPLY CHAIN QUALITATIVE PERFORMANCE

INTERNATIONAL REFEREED ACADEMIC SOCIAL SCIENCES JOURNAL, 2015
Tedarik zincirinin rekabet gücünü artırmada ve sağlamlaştırmada oynamış olduğu önemli role rağmen teknolojik gelişmeler, artan rekabet ve küreselleşme bu olguya daha karmaşık bir yapı kazandırmıştır ve bütün firmalar için hayati derecede önem taşıyan, firma işlevinin sistematik ve stratejik koordinasyonu durumunda olan tedarik zinciri, sunulan hizmet ...
Yunus Emre Bulut, Yazar Adı Yazar Soyadı, Ahmet Atakısı   +2 more
openaire   +3 more sources

Preferences of Pediatric Patients and Their Caregivers for Chemotherapy‐Induced Nausea and Vomiting Control Endpoints: A Mixed Methods Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Purpose Although not always achieved, complete chemotherapy‐induced nausea and vomiting (CINV) control is the conventional goal of CINV prophylaxis. In this two‐center, mixed‐methods study, we sought to understand the preferences of adolescent patients and family caregivers for CINV control endpoints.
Haley Newman, Tadi Hondonga, Alison Berry, Caitlin Elgarten, Jason Freedman, Katelyn Oranges, Sara McDonough, Caroline Diorio, L. Lee Dupuis   +8 more
wiley   +1 more source

Intravitreal GD2‐Specific Chimeric Antigen Receptor T‐Cell Therapy for Refractory Retinoblastoma

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Effective treatments for advanced, treatment‐resistant retinoblastoma (RB) remain limited. GD2‐specific chimeric antigen receptor (CAR) T cells show potent antitumor activity with minimal toxicity but have not previously been evaluated in RB.
Subongkoch Subhadhirasakul, Jatuporn Sujjitjoon, Pa‐thai Yenchitsomanus, Kridtin Jarutatsanangkoon, Ng Wei Loon, Kleebsabai Sanpakit, Jassada Buaboonnam, Chayamon Takpradit, Pornpimon Yuti, Nunghathai Sawasdee, Piriya Luangwattananun, Siripakorn Sangkitporn, Arnan Limmahachai, La‐ongsri Atchaneeyasakul   +13 more
wiley   +1 more source

Sequences selection research on over-voltage and over-current protection for intrinsic safety power supply

Gong-kuang zidonghua, 2019
Over-voltage and over-current protection are two forms of over-voltage and over-current protection sequences of intrinsic safety power supply. In order to study the influence of different protection sequence forms on safety performance of intrinsic ...
BAO Changjun, LI Jiping, GENG Wenjing, YU Zhixue, CUI Shijie   +4 more
doaj   +1 more source