Results 101 to 110 of about 326,663 (289)

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

Optimization Method for Combination of Residual Current Protection and Coincidence Brake Logic in a Low-Voltage Distribution System

open access: yesShanghai Jiaotong Daxue xuebao
Low-voltage distribution systems frequently experience leakage current accidents. However, it is challenging to distinguish fault characteristics in abnormal operating conditions, such as electric shock to biological organisms and three-phase imbalance ...
XU Han, ZHU Sanli, ZHANG Tengfei, CHEN Shu, LIU Mingxiang
doaj   +1 more source

The effects of superconductor-stabilizer interfacial resistance on quench of a pancake coil made out of coated conductor

open access: yes, 2010
We present the results of numerical analysis of normal zone propagation in a stack of $YBa_2Cu_3O_{7-x}$ coated conductors which imitates a pancake coil.
G A Levin   +10 more
core   +1 more source

Transient DC Over-Voltage Protection for ITER PF AC/DC Converter

open access: yesCPSS Transactions on Power Electronics and Applications, 2021
The International Thermonuclear Experimental Reactor (ITER) poloidal field (PF) AC/DC converters are composed by thyristor-based phase controlled converter modules. As the core component of ITER PF AC/DC converter, the thyristor is very sensitive to over-voltage and damaged in microseconds, therefore, the transient over-voltage protection strategy is ...
openaire   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

open access: yesMolecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller   +17 more
wiley   +1 more source

LIMITATION ОF FERRO-RESONANCE АND CUMULATIVE OVER-VOLTAGES BY WEAK NONLINEAR RESISTORS IN SWITCH GEAR WITH VOLTAGE TRANSFORMERS

open access: yesИзвестия высших учебных заведений и энергетических объединенний СНГ: Энергетика, 2005
Investigations results pertaining to ferro-resonance and cumulative over-voltages in switch gears by means of computer modeling are given in the paper. In order to solve the problem concerning limitation of ferro-resonance and cumulative over-voltages it
E. V. Dmitriev   +3 more
doaj  

A High-precision Current Sense Circuit with Trimming for DC-DC Converts

open access: yesMATEC Web of Conferences, 2018
A high-precision current sense circuit with trimming is proposed to realize the over-current protection of the power management chip and improve its conversion efficiency.
Duan Ning   +4 more
doaj   +1 more source

Two terminal current limiter [PDF]

open access: yes, 1970
Two terminal device protects dc electronic circuits and experimental solid state devices, and replaces fuses and circuit breakers directly. The device consists of two transistors and two resistors and draws its necessary supply voltage from power source ...
Doubt, L. S.
core   +1 more source

Broken Symmetry and Coherence of Molecular Vibrations in Tunnel Transitions

open access: yes, 2004
We examine the Breit-Wigner resonances that ensue from field effects in molecular single electron transistors (SETs). The adiabatic dynamics of a quantum dot elastically attached to electrodes are treated in the Born-Oppenheimer approach.
Dykhne, Alexander M.   +1 more
core   +3 more sources

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