Results 101 to 110 of about 329,153 (310)

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

Battery choice and management for New Generation Electric Vehicles [PDF]

open access: yes, 2005
Different types of electric vehicles (EVs) have been recently designed with the aim of solving pollution problems caused by the emission of gasoline-powered engines.
Affanni, A.   +4 more
core   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

Optimization Method for Combination of Residual Current Protection and Coincidence Brake Logic in a Low-Voltage Distribution System

open access: yesShanghai Jiaotong Daxue xuebao
Low-voltage distribution systems frequently experience leakage current accidents. However, it is challenging to distinguish fault characteristics in abnormal operating conditions, such as electric shock to biological organisms and three-phase imbalance ...
XU Han, ZHU Sanli, ZHANG Tengfei, CHEN Shu, LIU Mingxiang
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

A High-precision Current Sense Circuit with Trimming for DC-DC Converts

open access: yesMATEC Web of Conferences, 2018
A high-precision current sense circuit with trimming is proposed to realize the over-current protection of the power management chip and improve its conversion efficiency.
Duan Ning   +4 more
doaj   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

LIMITATION ОF FERRO-RESONANCE АND CUMULATIVE OVER-VOLTAGES BY WEAK NONLINEAR RESISTORS IN SWITCH GEAR WITH VOLTAGE TRANSFORMERS

open access: yesИзвестия высших учебных заведений и энергетических объединенний СНГ: Энергетика, 2005
Investigations results pertaining to ferro-resonance and cumulative over-voltages in switch gears by means of computer modeling are given in the paper. In order to solve the problem concerning limitation of ferro-resonance and cumulative over-voltages it
E. V. Dmitriev   +3 more
doaj  

Overload protection system for power inverter [PDF]

open access: yes, 1977
An overload protection system for a power inverter utilized a first circuit for monitoring current to the load from the power inverter to detect an overload and a control circuit to shut off the power inverter, when an overload condition was detected. At
Nagano, S.
core   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns   +10 more
wiley   +1 more source

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