Results 111 to 120 of about 326,663 (289)

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Research of lightning protection gap of 35 kV power line of coal mine

Gong-kuang zidonghua, 2013
In order to test lightning protection effect of protection gap for 35 kV power line, the paper simulated lightning invasion in 35 kV transformer taking 35 kV overhead line of a mine as model by use of ATP-EMPT electromagnetic transient analysis software,
DENG Jie-wen, REN Wen-bin, LIU Yuan, ZHANG Dong, YI Xiao-fei, LIAO Zhi-hua   +5 more
doaj  

Models and experimental results from the wide aperture Nb-Ti magnets for the LHC upgrade

, 2014
MQXC is a Nb-Ti quadrupole designed to meet the accelerator quality requirements needed for the phase-1 LHC upgrade, now superseded by the high luminosity upgrade foreseen in 2021. The 2-m-long model magnet was tested at room temperature and 1.9 K.
Auchmann, B., Bajko, M., Bourcey, N., Charrondiere, M., Datskov, V. I., Fessia, P., Feuvrier, J., Galbraith, P., Garcia-Perez, J., Granieri, P., Hagen, P., Kirby, G., Lorin, C., Perez, J. C., Russenschuck, S., Sahner, T., Segreti, M., Tabares, A. Garcia, Todesco, E., Willering, G.   +19 more
core   +1 more source

Tumor mutational burden as a determinant of metastatic dissemination patterns

Molecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal, Andrea Moreno‐Manuel, Miguel Salvadó‐Pertierra, Cristina Santos‐Vivas, Rebeca Sanz‐Pamplona   +4 more
wiley   +1 more source

Study of Emergency Power Based on Solar Battery Charging

MATEC Web of Conferences, 2016
To study an emergency power based on solar battery charging. Based on the electric-generation principle of solar panel, solar energy is changed into electrical energy.
Wang Lei, Zhu Mengfu, Chen Ping, Deng Cheng, Liu Zhimeng, Wang Yanan   +5 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Development of an internet of things-based monitoring system for small vertical axis wind turbine

Journal Geuthee of Engineering and Energy
Small-scale wind turbines often face challenges related to low energy conversion efficiency and the lack of adequate monitoring and automatic protection systems against fluctuating weather and load conditions.
Yuli Prasetyo, Budi Triyono, Budi Artono, Santi Triwijaya, Ainul Khakim, Ade Nofa Ramadhan   +5 more
doaj   +1 more source

Ground Fault Protection Using Open Break Delta Grounding Transformer in Ungrounded System

Logic, 2019
One of the most common and difficult problems to solve in distribution power systems is the location and elimination of the ground fault. For the study of an electrical distribution network in ungrounded system operating at 20 kV on the primary and 380 V
Supriyanto Suhono, Hari Purnama, Heri Budi Utomo   +2 more
doaj   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

Molecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon, Dong Young Kim, Yuna Kim, Uk‐Il Kim, Jae‐Sung Kim   +4 more
wiley   +1 more source