Results 61 to 70 of about 326,663 (289)

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Power quality in high-tech campus: an exemplary case study [PDF]

open access: yes, 2013
This paper presents preliminary results from a power quality audit conducted at a high-tech campus over last year. Voltage and current were measured at various R&D buildings.
González, Juan J.   +3 more
core  

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

FBG-based fibre-optic current sensors for power systems protection : laboratory evaluation [PDF]

open access: yes, 2009
Conventional differential current unit protection schemes rely on a pair of electronic protection relays that measure current phasors separately at the boundaries of the protected zone.
Booth, Campbell   +3 more
core  

Development and test of resistive superconducting fault current limiter; acting time and its recovery conditions [PDF]

open access: yes, 2014
Resistive-type of superconducting fault current limiters (RSFCL) have been developed for medium voltage class aiming to operate at 1 MVA power capacity and short time recovery (< 2 s).
Baldan, Carlos A   +4 more
core   +2 more sources

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

NONLINEAR OVERVOLTAGE LIMITER APPLICATION FOR INTERNAL OVER-VOLTAGE PROTECTION IN AVERAGE VOLTAGE NETWORKS

open access: yesИзвестия высших учебных заведений и энергетических объединенний СНГ: Энергетика, 2005
Review of internal over-voltages in distribution networks 6…10 kV and means of their limitation has been carried out. One of the most efficient remedy for reduction of over-voltage at arcing ground is resistive neutral grounding.
A. N. Bokhan, V. V. Krotenok
doaj  

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Research on transient energy suppression strategy of intrinsically safe output power supply for mine

open access: yesMeikuang Anquan
In response to the requirements of GB/T 3836.4—2021 Explosive atmosphere Part 4: Equipment with protection by intrinsic safety “i” for outputting transient energy of intrinsically safe power sources based on the principle of semiconductor rapid short ...
Changna GUO
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

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