Results 71 to 80 of about 82,834 (266)

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Optimization Method for Combination of Residual Current Protection and Coincidence Brake Logic in a Low-Voltage Distribution System

Shanghai Jiaotong Daxue xuebao
Low-voltage distribution systems frequently experience leakage current accidents. However, it is challenging to distinguish fault characteristics in abnormal operating conditions, such as electric shock to biological organisms and three-phase imbalance ...
XU Han, ZHU Sanli, ZHANG Tengfei, CHEN Shu, LIU Mingxiang
doaj   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Research of lightning protection gap of 35 kV power line of coal mine

Gong-kuang zidonghua, 2013
In order to test lightning protection effect of protection gap for 35 kV power line, the paper simulated lightning invasion in 35 kV transformer taking 35 kV overhead line of a mine as model by use of ATP-EMPT electromagnetic transient analysis software,
DENG Jie-wen, REN Wen-bin, LIU Yuan, ZHANG Dong, YI Xiao-fei, LIAO Zhi-hua   +5 more
doaj  

A High-precision Current Sense Circuit with Trimming for DC-DC Converts

MATEC Web of Conferences, 2018
A high-precision current sense circuit with trimming is proposed to realize the over-current protection of the power management chip and improve its conversion efficiency.
Duan Ning, Liu Shulin, Zhu Xiangdong, Pei Jinjun, Zhu Haipeng   +4 more
doaj   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

LIMITATION ОF FERRO-RESONANCE АND CUMULATIVE OVER-VOLTAGES BY WEAK NONLINEAR RESISTORS IN SWITCH GEAR WITH VOLTAGE TRANSFORMERS

Известия высших учебных заведений и энергетических объединенний СНГ: Энергетика, 2005
Investigations results pertaining to ferro-resonance and cumulative over-voltages in switch gears by means of computer modeling are given in the paper. In order to solve the problem concerning limitation of ferro-resonance and cumulative over-voltages it
E. V. Dmitriev, A. M. Gashimov, I. R. Pivchik, S. I. Gasanova   +3 more
doaj  

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

Study of Emergency Power Based on Solar Battery Charging

MATEC Web of Conferences, 2016
To study an emergency power based on solar battery charging. Based on the electric-generation principle of solar panel, solar energy is changed into electrical energy.
Wang Lei, Zhu Mengfu, Chen Ping, Deng Cheng, Liu Zhimeng, Wang Yanan   +5 more
doaj   +1 more source