Results 71 to 80 of about 11,977,292 (286)
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
IEEE AccessThe implementation of low-voltage-ride-through (LVRT) requirements for distributed generation (DG) sources in medium voltage (MV) distribution networks introduce challenges for the existing protection systems.
Anoop V. Eluvathingal, K. Shanti Swarup
doaj +1 more source
Investigation of surge propagation in transient voltage surge suppressors and experimental verification [PDF]
, 2014 An on-going question in the field of surge protection study is how to predict incipient failure of power electronics in the event of a short time, high voltage, and high energy transient surge propagation.
James, Sisira
core
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
1.7 kV IGBT Driver Based on Electromagnetism Isolation
Kongzhi Yu Xinxi Jishu, 2015 The basic characteristics of IGBT driver were analyzed and an IGBT driver based on electromagnetism isolation was designed. Chopping and short-circuit test researches on the driver were executed.
XIE Shunmeng +4 more
doaj
The microbiome in human skin aging
FEBS Letters, EarlyView.Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana +3 more
wiley +1 more source
Protection of Transistors against over Voltage in Video Amplifiers
The Journal of the Institute of Television Engineers of Japan, 1963 映像機器にトランジスタが多用されるに従い, トランジスタ機器では真空管機器で従来あまり経験されなかった事故がしばしば発生することがある.このような問題点の一つである入力過大電圧によるトランジスタ増幅器の破損を取り上げ, 保護回路の設計要旨と実際についてのべる.
Marubayasi, Hiroshi +2 more
openaire +2 more sources
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
FEBS Letters, EarlyView.In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source