Results 61 to 70 of about 11,977,292 (286)
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
It analyzed the generation mechanism of surge voltage during IGBT switching-off in inverter, illustrated the design method of laminated bus-bar for low parasitic inductance, and put forward the design methods of absorption circuit for switching-off surge
ZHU Shiwu, HUANG Changqiang, HUANG Cheng
doaj
To address the problems of poor speed performance and the large influence of the distributed capacitance of traditional pilot differential protection, a pilot protection scheme based on the characteristics of the transient voltage waveform is proposed ...
Zhijie Wang +5 more
doaj +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Over Voltage Protection for Household Equipments
This paper identifies the development of an over voltage protection in order to avoid damage in load side. Most of home appliances are expensive also more sensitive. This may get damaged due to the instabilities in ac mains supply. It can also lead to losses in the electrical circuit. These losses lead to low power factors and wastage of so much power.
openaire +1 more source
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
Structure‐forward targeting of claudins with synthetic binders
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
On the basis of the developed device for protection against of ferro-resonant and high-frequency cumulative over-voltages an algorithm for obtaining a voltage imitating ferro-resonant over-voltages is proposed in the paper.
Ye. V. Dmitriev +2 more
doaj
INTRODUCTION: Renewable energy represented by grid forming inverter interfaced distributed energy resources is increasingly connected to microgrids that can operate independently and have various modes, resulting in traditional relay protection schemes ...
Yubo Yuan +4 more
doaj +1 more source

