Results 41 to 50 of about 25,460 (223)

Role of detrusor PDGFRα+ cells in Cyclophosphamide-induced Detrusor Overactivity [PDF]

, 2021
Abstract Cyclophosphamide (CYP)-induced cystitis is a rodent model that shares many features common to the cystitis occurring in patients, including detrusor overactivity (DO). Platelet-derived growth factor receptor alpha positive (PDGFRα+) cells regulate muscle excitability in murine bladders during filling.
Haeyeong Lee, Byoung H. Koh, Lauren E. Peri, Holly J. Woodward, Brian A. Perrino, Kenton M. Sanders, Sang Don Koh   +6 more
openaire   +1 more source

Botulinum toxin A for the treatment of neurogenic detrusor overactivity in multiple sclerosis patients

International Brazilian Journal of Urology, 2011
PURPOSE: Neurogenic detrusor overactivity (NDO) is common in patients who suffer from multiple sclerosis (MS). When the usual pharmacological treatment fails, botulinum toxin type A (BTX-A) injections can be proposed.
S. Deffontaines-Rufin, M. Weil, D. Verollet, L. Peyrat, G. Amarenco   +4 more
doaj   +1 more source

Emergencies in Amyotrophic Lateral Sclerosis

Muscle &Nerve, EarlyView.
ABSTRACT Emergencies are frequent in people living with amyotrophic lateral sclerosis (pALS), especially as the disease progresses, and can necessitate urgent evaluation and intervention. Progressive weakness in ALS inevitably increases fall risk, making discussion of fall prevention strategies integral to caring for pALS.
S. Pinar Uysal, Katherine A. Dudley, Stacey Sullivan, Kate T. Brizzi, Katherine M. Burke, Sydney Hall, Kiersten Pease, Joshua N. Goldstein, James D. Berry, Doreen T. Ho   +9 more
wiley   +1 more source

Impact of Overactive Bladder Syndrome on Female Sexual Function

, 2015
The etiology of female sexual dysfunction includes psychological, physiological and iatrogenic causes. Physiological and iatrogenic causes are abdominal surgery, menopause, smoking, spinal cord injuries and some antipsychotic, antihypertensive, and ...
Taha Numan Yıkılmaz, Serdar Toksöz
core   +1 more source

Investigations into the presence of functional ß1, ß2 and ß3-adrenoceptors in urothelium and detrusor of human bladder

International Brazilian Journal of Urology, 2009
Purpose: We investigated the presence of functional ß1, ß2 and ß3-adrenoceptor in urothelium and detrusor muscle of human bladder through in vitro pharmacology of selective ß3 adrenoceptor agonist solabegron.
Pradeep Tyagi, Catherine A. Thomas, Naoki Yoshimura, Michael B. Chancellor   +3 more
doaj   +1 more source

Clinical application of intravesical botulinum toxin type A for overactive bladder and interstitial cystitis [PDF]

Investigative and Clinical Urology, 2020
After decades of clinical and basic science research, the clinical application of botulinum toxin A (Botox) in urology has been extended to neurogenic detrusor overactivity (NDO), idiopathic detrusor overactivity, refractory overactive bladder (OAB ...
Jing-Liang Chen , Hann-Chorng Kuo
doaj   +1 more source

Fascial Mid‐Urethral Sling or Artificial Urinary Sphincter in Women With Neurological Diseases, a Multicenter Study

Neurourology and Urodynamics, EarlyView.
ABSTRACT Background Achieving continence in patients with neurogenic bladder is a difficult goal especially when stress urinary incontinence (SUI) due to intrinsic sphincter deficiency is involved. Two techniques are commonly used in that setting, but they have never been directly compared: the artificial urinary sphincter (AUS) and the fascial ...
Alicia Blondeau, Charles Mazeaud, Rose Khavari, Melody Ong, Alexandre Dubois, Alice Pitout, Pierre Lecoanet, Benoit Peyronnet   +7 more
wiley   +1 more source

Urodynamic Voiding Patterns in Multiple Sclerosis. [PDF]

Neurourol Urodyn
ABSTRACT Aims This study aimed to describe urodynamic voiding patterns in patients with MS (PwMS) using standardized assessments, and to compare the performance of the available nomograms and indices for obstruction and bladder contractility. Methods PwMS and lower urinary tract symptoms underwent cystometry and pressure flow studies.
Chesnel C, Turmel N, Teng M, Blouet E, Amarenco G, Hentzen C.   +5 more
europepmc   +2 more sources

Non‐Invasive Triage of Bladder Outlet Obstruction and Detrusor Underactivity in Men With Lower Urinary Tract Symptoms: A Narrative Review and Conceptual Framework for Depth‐Aware Multimodal Transcutaneous Testing

Neurourology and Urodynamics, EarlyView.
ABSTRACT Introduction Differentiating bladder outlet obstruction (BOO) from detrusor underactivity (DU) remains a major unmet need in the management of lower urinary tract symptoms in men. Although pressure–flow urodynamics provide a definitive physiological classification, their invasiveness limits their widespread use.
Sehwan Kim, Bryan K. Kim, John T. Stoffel, Aram Kim   +3 more
wiley   +1 more source

Isotretinoin induced overactive bladder – a novel case and review of literature

Continence Reports
We present the case of a 29-year-old male who developed new-onset overactive bladder (OAB) symptoms shortly after commencing oral isotretinoin for acne. No alternative cause was identified, and urodynamics revealed no detrusor overactivity. Isotretinoin,
Rowan Klein Nulend, Mohan Arianayagam, Audrey Wang   +2 more
doaj   +1 more source