Results 1 to 10 of about 25,370 (238)

Virulence Mechanisms of Common Uropathogens and Their Intracellular Localisation within Urothelial Cells

Pathogens, 2022
A recurrent urinary tract infection (UTI) is a common debilitating condition whereby uropathogens are able to survive within the urinary tract. In this study, we aimed to determine if the common uropathogens Escherichia coli, Enterococcus faecalis, and ...
Samantha Ognenovska, Chinmoy Mukerjee, Martina Sanderson-Smith, Kate H. Moore, Kylie J. Mansfield   +4 more
doaj   +1 more source

Patient characteristics, symptoms, and urodynamic parameters associated with detrusor contraction duration in women

Frontiers in Urology, 2023
BackgroundThere is a lack of understanding of the clinical significance of detrusor contraction duration (DCD) measured on urodynamic studies (UDS). We aimed to identify patient characteristics, presenting symptoms and urodynamic parameters associated ...
Connie N. Wang, Albert Ha, Doreen E. Chung   +2 more
doaj   +1 more source

Differences in the Urinary Microbiome of Patients with Overactive Bladder Syndrome with and without Detrusor Overactivity on Urodynamic Measurements

Life, 2023
Introduction: It has been hypothesized that the urinary microbiome might play an important role in OAB. Studies have been conducted on the association between OAB symptoms and the microbiome, although a possible causality still has to be determined ...
Aida Javan Balegh Marand, Cléo Baars, John Heesakkers, Ellen van den Munckhof, Morteza Ghojazadeh, Mohammad Sajjad Rahnama’i, Dick Janssen   +6 more
doaj   +1 more source

Frontiers in the Clinical Applications of Botulinum Toxin A as Treatment for Neurogenic Lower Urinary Tract Dysfunction [PDF]

International Neurourology Journal, 2020
Patients with neurogenic lower urinary tract dysfunction (NLUTD) experience urinary incontinence with or without difficult urination, which might promote recurrent urinary tract infection (UTI) and exacerbate upper urinary tract function.
Yuan-Hong Jiang, Sheng-Fu Chen, Hann-Chorng Kuo   +2 more
doaj   +1 more source

Detrusor Smooth Muscle KV7 Channels: Emerging New Regulators of Urinary Bladder Function

Frontiers in Physiology, 2020
Relaxation and contraction of the urinary bladder smooth muscle, also known as the detrusor smooth muscle (DSM), facilitate the micturition cycle. DSM contractility depends on cell excitability, which is established by the synchronized activity of ...
John Malysz, Georgi V. Petkov, Georgi V. Petkov, Georgi V. Petkov   +3 more
doaj   +1 more source

Application of Vesical Imaging–Reporting and Data System in Evaluation of Urinary Bladder Cancer Using Multiparametric Magnetic Resonance Imaging: A Hospital-Based Cross-Sectional Study

Avicenna Journal of Medicine, 2022
Background Multiparametric magnetic resonance imaging (mp-MRI) of urinary bladder (UB) is a novel imaging to predict detrusor muscle invasion in Bladder cancer (BC).
Rahul Gupta, Manik Mahajan, Poonam Sharma, Subhash Bhardwaj, Vikrant Gupta, Arti Mahajan   +5 more
doaj   +1 more source

Drugs Currently Undergoing Preclinical or Clinical Trials for the Treatment of Overactive Bladder: A Review

Current Therapeutic Research, 2022
: Background: Overactive bladder (OAB) is a common clinical condition for which current drug treatment comprises drugs blocking the cholinergic nerve supply, or augmenting the adrenergic nerve supply, to the detrusor muscle of the urinary bladder ...
Silvia Joseph, MBBS, Steffi A. Maria, MD, Jacob Peedicayil, MD   +2 more
doaj   +1 more source

Site-Specific Neuromodulation of Detrusor and External Urethral Sphincter by Epidural Spinal Cord Stimulation

Frontiers in Systems Neuroscience, 2020
Impairments of the lower urinary tract function including urine storage and voiding are widely spread among patients with spinal cord injuries. The management of such patients includes bladder catheterization, surgical and pharmacological approaches ...
Yuriy Sysoev, Yuriy Sysoev, Elena Bazhenova, Elena Bazhenova, Vsevolod Lyakhovetskii, Vsevolod Lyakhovetskii, Gleb Kovalev, Polina Shkorbatova, Regina Islamova, Natalia Pavlova, Natalia Pavlova, Oleg Gorskii, Oleg Gorskii, Oleg Gorskii, Natalia Merkulyeva, Natalia Merkulyeva, Natalia Merkulyeva, Dmitry Shkarupa, Pavel Musienko, Pavel Musienko, Pavel Musienko, Pavel Musienko   +21 more
doaj   +1 more source

Detrusor-Overactivity-Related Voiding in Women Mimics Bladder Outflow Obstruction and Conceals Underactivity

Urology Research and Practice, 2023
Objective: Urodynamics of the storage phase showing detrusor overactivity is com- mon in neurogenic bladder patients. Terminal detrusor overactivity, which is defined by involuntary detrusor contraction that cannot be inhibited, causes urinary incon ...
Takeya Kitta, Yui Abe-Takahashi, Mifuka Ouchi, Mayuko Tsukiyama, Naohisa Kusakabe, Madoka Higuchi, Hiroki Chiba, Mio Togo, Shinya Kobayashi, Nobuo Shinohara   +9 more
doaj   +1 more source

Porcine bladder urothelial, myofibroblast and detrusor muscle cells: characterisation and ATP release

Frontiers in Pharmacology, 2011
ATP is released from the bladder mucosa in response to stretch, but the cell types responsible are unclear. Our aim was to isolate and characterise individual populations of urothelial, myofibroblast and detrusor muscle cells in culture, and to examine ...
Ying eCheng, Kylie eMansfield, Shaun eSandow, Prajni eSadananda, Elizabeth eBurcher, Kate eMoore   +5 more
doaj   +1 more source