Results 11 to 20 of about 25,370 (238)

Detrusor Sphincter Dyssynergia. [PDF]

Urologic Clinics of North America
Detrusor sphincter dyssynergia (DSD) is defined as a detrusor contraction concurrent with an involuntary contraction of the urethral and/or periurethral striated muscles typically occurring in a patient with a spinal cord lesion above the sacral cord ...
Kessler, Thomas M, Furrer, Marc A, Panicker, Jalesh N   +2 more
core   +6 more sources

Improved model for the establishment and evaluation of detrusor overactivity in female Wistar rats

International Brazilian Journal of Urology, 2014
Objective To improve the model for establishment and evaluation of detrusor overactivity in female Wistar rats. Materials and Methods We ligated the perineal urethra of female Wistar rats and then performed filling cystometry.
Nian-zhao Zhang, Lin Ma, Jian-bo Zhang, Jun Chen   +3 more
doaj   +3 more sources

Detrusor Arreflexia as an End Stage of Neurogenic Bladder in HAM/TSP? [PDF]

Case Reports in Medicine, 2011
The HTLV-1 virus is a known agent involved in the development of HAM/TSP. Past studies have typically observed patients with autonomic dysfunction consisting of detrusor overactivity and detrusor-sphincter dyssynergia, with the occasional observation of
Matheus Tannus, Davi Tanajura, Michael A. Sundberg, Paulo Oliveira, Neviton Castro, André Muniz Santos   +5 more
doaj   +2 more sources

Lower Urinary Tract Symptoms as Diagnostic Clues in Parkinsonism: A Practical Framework for Neurologists. [PDF]

Mov Disord Clin Pract
Abstract Background Lower urinary tract symptoms (LUTS) are among the most prevalent nonmotor complaints across the parkinsonian spectrum, yet they remain underutilized as diagnostic and management signals in neurology practice. Although prior reviews have characterized disease‐specific patterns of urinary dysfunction, and recent guidelines address ...
Anis S, Anis O, Lenka A, Siddiqui JH.
europepmc   +2 more sources

Botulinum toxin-A for the treatment of overactive bladder: UK contributions [PDF]

, 2013
Background: Botulinum toxin-A (BoNT/A) is now established second-line management for refractory overactivebladder (OAB) and recognised in many incontinence guidelines and pathways.
Fowler, CJ, Panicker, J. N., Fowler, C. J., Dowson, C, Khan, MS, Seth, JH, Dasgupta, P, Dasgupta, P., Panicker, JN, Sahai, A, Dowson, C., Seth, J. H., Khan, M. S., Sahai, Arun   +13 more
core   +1 more source

Hyperglycemic memory in the rat bladder detrusor is associated with a persistent hypomethylated state

Physiological Reports, 2020
Hyperglycemic memory is associated with several complications of diabetes. Although there is some physiological evidence that this phenomenon occurs with diabetic bladder dysfunction (DBD), there have been no studies in bladder that provide evidence of ...
Yi Wang, Moses T. Tar, Kelvin P. Davies
doaj   +1 more source

Age‐dependent decrease in TRPM4 channel expression but not trafficking alters urinary bladder smooth muscle contractility

Physiological Reports, 2021
During development, maturation, or aging, the expression and function of urinary bladder smooth muscle (UBSM) ion channels can change, thus affecting micturition.
Sarah E. Maxwell, M. Dennis Leo, John Malysz, Georgi V. Petkov   +3 more
doaj   +1 more source

Analysis of spontaneous depolarization-linked hyperpolarizations in mouse detrusor smooth muscle cells

Biomedical Research Journal, 2019
Background: Urinary bladder detrusor smooth muscle cells exhibit spontaneous electrical activities comprising various signal types. Aims and Objectives: This article introduces and analyzes a rare category of signals observed in such activity, named ...
Mithun Padmakumar, Keith L Brain, Rohit Manchanda   +2 more
doaj   +1 more source

Concomitant Detrusor and External Urethral Sphincter Botulinum Toxin-A Injections in Male Spinal Cord Injury Patients with Detrusor Overactivity and Detrusor Sphincter Dyssynergia

Journal of Rehabilitation Medicine, 2022
Objective: To investigate the effects of concomitant injections of botulinum toxin-A (BoNT-A) into the detrusor and external urethral sphincter muscles in suprasacral spinal cord injured patients with detrusor overactivity and detrusor sphincter ...
Yu-Hui Huang, Sung-Lang Chen
doaj   +1 more source

Inhibition of Contractility of Isolated Caprine Detrusor by the Calcium Channel Blocker Cilnidipine and Reversal by Calcium Channel Openers

Current Therapeutic Research, 2023
: Background: Cilnidipine is a fourth-generation calcium channel blocker that is clinically used to treat hypertension. It is a dihydropyridine that blocks L- and N-type calcium channels.
Steffi A. Maria, MD, Aniket Kumar, PhD, Premila M. Wilfred, MD, Margaret Shanthi, MD, Jacob Peedicayil, MD   +4 more
doaj   +1 more source