Results 1 to 10 of about 4,974 (168)

Urea Transporter UT-B Deletion Induces DNA Damage and Apoptosis in Mouse Bladder Urothelium [PDF]

PLoS ONE, 2013
BackgroundPrevious studies found that urea transporter UT-B is abundantly expressed in bladder urothelium. However, the dynamic role of UT-B in bladder urothelial cells remains unclear.
Guiting Lin, Lise Bankir, Baoxue Yang
exaly   +3 more sources

Signalling Molecules in the Urothelium [PDF]

BioMed Research International, 2014
The urothelium was long considered to be a silent barrier protecting the body from the toxic effects of urine. However, today a number of dynamic abilities of the urothelium are well recognized, including its ability to act as a sensor of the intravesical environment. During recent years several pathways of these urothelial abilities have been proposed
Winder, Michael, Tobin, Gunnar, Zupančič, Daša, Romih, Rok   +3 more
core   +5 more sources

Vesical Urothelium and New Concepts

Urologia Journal, 2012
Vesical urothelium was long considered to simply be a protection barrier, which passively separates the urinary content from the underlying smooth muscle and the blood stream. Recent observations, though, have pointed out that vesical urothelium cells have clear active and sensory functions, in response to various physical and chemical stimuli.
GIANNANTONI, Antonella, PROIETTI, SILVIA, GIOVANNOZZI, SILVIA, PORENA, Massimo   +3 more
core   +5 more sources

Characterization of muscarinic and P2X receptors in the urothelium and detrusor muscle of the rat bladder [PDF]

Journal of Pharmacological Sciences, 2016
Muscarinic and purinergic (P2X) receptors play critical roles in bladder urothelium under physiological and pathological conditions. Aim of present study was to characterize these receptors in rat bladder urothelium and detrusor muscle using selective ...
Masaki Ogoda, Yoshihiko Ito, Yusuke Fuchihata, Satomi Onoue, Shizuo Yamada   +4 more
doaj   +2 more sources

Bilateral tumors of the upper urothelium [PDF]

Srpski arhiv za celokupno lekarstvo, 2006
Introduction: The incidence of tumors of the upper urothelium is high in our country, apart from their relation to specific regions (BEN and PBEN) and their frequent bilateralism. Bilateral forms are present in significant percentage and are followed, in most cases, by renal failure, which speaks in favor of conservative surgery, if possible. Objective:
Đokić Milan, Dragičević Dejan, Nikolić Jovan, Dragićević Svetomir, Radivojević Dragana   +4 more
openaire   +5 more sources

Cascade bioassay evidence for the existence of urothelium-derived inhibitory factor in Guinea pig urinary bladder. [PDF]

PLoS ONE, 2014
Our aim was to investigate whether guinea pig urothelium-derived bioactivities compatible with the existence of urothelium-derived inhibitory factor could be demonstrated by in vitro serial bioassay and whether purinergic P1 receptor agonists, nitric ...
Na N Guan, Anna Thor, Katarina Hallén, N Peter Wiklund, Lars E Gustafsson   +4 more
doaj   +2 more sources

POMC expression of the urothelium of the urinary bladder of mice submitted to pelvic radiation

European Journal of Inflammation, 2016
Objective: Patients who have had pelvic radiotherapy as part of their cancer therapy may develop subsequent urinary bladder injury. The acute changes that the urothelium undergo after radiation are known, but the healing mechanism of the urothelium of ...
M Kemal Ozbilgin, Caner Aktas, Merve Temel, Tuna Önal, Elgin Türköz Uluer, H Seda Vatansever, Cengiz Kurtman   +6 more
doaj   +2 more sources

Is electrolyte transfer across the urothelium important?: ICI-RS 2015 [PDF]

, 2017
AIMS:This article summarizes discussion at the International Consultation on Incontinence Research Society (ICI-RS) 2015 meeting of urine modification in the urinary tract by the urothelium.
Vahabi, Bahareh, Fry, CH, McCluskey, KD
core   +6 more sources

Prognostic impact of perirenal fat stranding on oncologic outcomes in ureteral urothelial carcinoma [PDF]

Investigative and Clinical Urology, 2021
Purpose: Perirenal fat stranding (PRFS) is defined as linear areas of soft-tissue attenuation in the perirenal space that can result from ureteral obstruction.
Jae-Wook Chung , Jun Nyung Lee , Kyong Min Park , Kyeong Hyeon Byeon , Hyejin Cheon , Yun-Sok Ha , Seock Hwan Choi , Bum Soo Kim , Tae-Hwan Kim , Eun Sang Yoo , Tae Gyun Kwon , Hyun Tae Kim   +11 more
doaj   +1 more source

β₃ Relaxant Effect in Human Bladder Involves Cystathionine γ-Lyase-Derived Urothelial Hydrogen Sulfide

Antioxidants, 2022
It is now well established that the urothelium does not act as a passive barrier but contributes to bladder homeostasis by releasing several signaling molecules in response to physiological and chemical stimuli.
Emma Mitidieri, Annalisa Pecoraro, Erika Esposito, Vincenzo Brancaleone, Carlotta Turnaturi, Luigi Napolitano, Vincenzo Mirone, Ferdinando Fusco, Giuseppe Cirino, Raffaella Sorrentino, Giulia Russo, Annapina Russo, Roberta d’Emmanuele di Villa Bianca   +12 more
doaj   +1 more source