The Current Use of Stem Cells in Bladder Tissue Regeneration and Bioengineering [PDF]
Biomedicines, 2017 Many pathological processes including neurogenic bladder and malignancy necessitate bladder reconstruction, which is currently performed using intestinal tissue. The use of intestinal tissue, however, subjects patients to metabolic abnormalities, bladder
Yvonne Y. Chan +3 more
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Enhanced Adenosine Triphosphate Release From the Urothelium of Patients With Painful Bladder Syndrome: A Possible Pathophysiological Explanation [PDF]
Journal of Urology, 2007 Purpose: We established the level of adenosine triphosphate release by the urothelium in patients with painful bladder syndrome and compared it with that from the normal human bladder.
Christopher R Chapple +1 more
exaly +3 more sources
Urea Transporter UT-B Deletion Induces DNA Damage and Apoptosis in Mouse Bladder Urothelium [PDF]
PLoS ONE, 2013 BackgroundPrevious studies found that urea transporter UT-B is abundantly expressed in bladder urothelium. However, the dynamic role of UT-B in bladder urothelial cells remains unclear.
Jihui Chen, Tianluo Lei, Lise Bankir
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Spatial transcriptomic map of the mouse urinary bladder [PDF]
Scientific ReportsWe present a spatial transcriptomic map of the mouse urinary bladder at near single-cell resolution using Visium HD technology with 8 × 8 μm bins. After quality filtering, we analyzed 66,471 bins and 9,364 genes.
Nives Matković +10 more
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The Urothelium: Life in a Liquid Environment
Physiological Reviews, 2020 The urothelium, which lines the renal pelvis, ureters, urinary bladder, and proximal urethra, forms a high-resistance but adaptable barrier that surveils its mechanochemical environment and communicates changes to underlying tissues including afferent nerve fibers and the smooth muscle.
Marianela G Dalghi +2 more
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Modulation of lower urinary tract smooth muscle contraction and relaxation by the urothelium [PDF]
Naunyn-Schmiedeberg's Archives of Pharmacology, 2018 The epithelial inner layer of the lower urinary tract, i.e., the urothelium, and other parts of the mucosa are not just a passive barrier but play an active role in the sensing of stretching, neurotransmitters, paracrine mediators, hormones, and growth ...
Donna J Sellers +2 more
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CBD Promotes Structural and Functional Epithelial Restoration and Alleviates Inflammation in a Mouse Model of Interstitial Cystitis [PDF]
PharmaceuticsBackground: Interstitial cystitis (IC) is a debilitating lower urinary tract condition characterised by chronic inflammation of the bladder. As the aetiology remains unknown, current treatments are symptomatic, aiming to reduce inflammation and pain ...
Dominika Peskar +6 more
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Acellular foreskin dermal matrix is efficient in supporting the growth of urothelial cells derived from hypospadias patients [PDF]
Frontiers in PediatricsIntroductionHypospadias is a common congenital defect in males, with surgery remaining the primary treatment option. However, urethral reconstruction procedures often require additional tissue transplantation, which is limited by the availability of ...
Zhiqing Cao +4 more
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PPARγ promotes urothelial remodeling during urinary tract obstruction [PDF]
Experimental and Molecular MedicineUrinary tract obstruction (UTO) is a common cause of kidney injury that can result in chronic kidney disease and end-stage renal disease. Heterogeneity in the extent of obstructive renal damage in humans with UTO implies the existence of unknown ...
Mohammad El-Harakeh +11 more
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BEES-HAUS preventing urethral stricture recurrence by restoring the integrity of urothelium and its further simplified version, the BHES-HAUS [PDF]
Frontiers in Bioengineering and BiotechnologyGraphical AbstractDiagram illustrating interventional treatment approaches for urethral stricture, emphasizing urothelial integrity in preventing stricture recurrence.
Akio Horiguchi +9 more
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