Results 21 to 30 of about 14,292 (181)

Urothelial cancers of the bladder in young people [PDF]

open access: yesVojnosanitetski Pregled, 2003
Tumors of the bladder, particularly urothelial carcinoma (UC) are very rare malignant diseases in young people. They mostly occur in elder persons of male gender.
Živković Slađana   +4 more
doaj   +1 more source

P2X7 Receptor Blockade Protects Against Acrolein-Induced Bladder Damage: A Potential New Therapeutic Approach for the Treatment of Bladder Inflammatory Diseases

open access: yesFrontiers in Pharmacology, 2021
Inflammatory conditions of the urinary bladder have been shown to be associated with urothelial damage and loss of function. The purinergic P2X7 receptor has been implicated in several inflammatory conditions. The aim of this study was to investigate the
Zhinoos Taidi   +4 more
doaj   +1 more source

Role of ERK signaling in bladder urothelium in response to cyclophosphamide injury

open access: yesPhysiological Reports, 2022
Mice with inducible urothelial deletion of fibroblast growth factor receptor 2 (ShhCreERT2;Fgfr2Fl/Fl) injured with cyclophosphamide had aberrant basal cell endoreplication and poor regeneration.
Sridhar Tatarao Narla   +8 more
doaj   +1 more source

Recurrent Urinary Tract Infection: A Mystery in Search of Better Model Systems

open access: yesFrontiers in Cellular and Infection Microbiology, 2021
Urinary tract infections (UTIs) are among the most common infectious diseases worldwide but are significantly understudied. Uropathogenic E. coli (UPEC) accounts for a significant proportion of UTI, but a large number of other species can infect the ...
Benjamin O. Murray   +8 more
doaj   +1 more source

A Systematic Review of the (Un)known Host Immune Response Biomarkers for Predicting Recurrence of Urinary Tract Infection

open access: yesFrontiers in Medicine, 2022
Recurrent urinary tract infections (rUTI) represent a major healthcare and economic burden along with a significant impact on patient’s morbidity and quality of life, even in the absence of well-known risk factors, such as vesicoureteral reflux.
Iva Sorić Hosman   +4 more
doaj   +1 more source

Aging-Associated Changes in Oxidative Stress Negatively Impacts the Urinary Bladder Urothelium [PDF]

open access: yesInternational Neurourology Journal, 2022
Purpose Lower urinary tract symptoms are known to significantly increase with age, negatively impacting quality of life and self-reliance. The urothelium fulfills crucial tasks, serving as a barrier protecting the underlying bladder tissue from the harsh
Mathijs M. de Rijk   +6 more
doaj   +1 more source

Signalling Molecules in the Urothelium [PDF]

open access: yesBioMed Research International, 2014
The urothelium was long considered to be a silent barrier protecting the body from the toxic effects of urine. However, today a number of dynamic abilities of the urothelium are well recognized, including its ability to act as a sensor of the intravesical environment. During recent years several pathways of these urothelial abilities have been proposed
Winder, Michael   +3 more
openaire   +2 more sources

Characterization of muscarinic and P2X receptors in the urothelium and detrusor muscle of the rat bladder

open access: yesJournal of Pharmacological Sciences, 2016
Muscarinic and purinergic (P2X) receptors play critical roles in bladder urothelium under physiological and pathological conditions. Aim of present study was to characterize these receptors in rat bladder urothelium and detrusor muscle using selective ...
Masaki Ogoda   +4 more
doaj   +1 more source

Cascade bioassay evidence for the existence of urothelium-derived inhibitory factor in Guinea pig urinary bladder.

open access: yesPLoS ONE, 2014
Our aim was to investigate whether guinea pig urothelium-derived bioactivities compatible with the existence of urothelium-derived inhibitory factor could be demonstrated by in vitro serial bioassay and whether purinergic P1 receptor agonists, nitric ...
Na N Guan   +4 more
doaj   +1 more source

Clinical impact of bladder biopsies with TUR-BT according to cytology results in patients with bladder cancer: a case control study

open access: yesBMC Urology, 2010
Background There seems to be no consensus concerning taking bladder biopsies during transurethral resection of bladder tumor (TUR-BT). We investigate the clinical significance of bladder biopsy with TUR-BT and the relationship between urinary cytology ...
Matsumoto Kazuhiro   +5 more
doaj   +1 more source

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