Cells in Urothelium Tissue Engineering
International audienceUrothelium is a highly specialized epithelium covering the entire urinary excretory system. Tissue engineering of this urinary tract may allow to consider its reconstruction to perform in vitro studies or in vivo replacement ...
Gillet, Pierre +13 more
core +1 more source
Diabetes-induced alterations in urothelium function:Enhanced ATP release and nerve-evoked contractions in the streptozotocin rat bladder [PDF]
Up to 80% of patients with diabetes mellitus develop lower urinary tract complications, most commonly diabetic bladder dysfunction (DBD). The aim of this study was to investigate the impact of diabetes on the function of the inner bladder lining ...
Rose'meyer, Roselyn +9 more
core +1 more source
Background There seems to be no consensus concerning taking bladder biopsies during transurethral resection of bladder tumor (TUR-BT). We investigate the clinical significance of bladder biopsy with TUR-BT and the relationship between urinary cytology ...
Matsumoto Kazuhiro +5 more
doaj +1 more source
Improved Urothelial Cell Proliferation, Cytoskeleton and Barrier Function Protein Expression in the Patients With Interstitial Cystitis/Bladder Pain Syndrome After Intravesical Platelet-Rich Plasma Injection [PDF]
Purpose To investigate urothelial cell proliferation, cytoskeleton, inflammation, and barrier function protein expressions in patients with interstitial cystitis/bladder pain syndrome (IC/BPS) after intravesical platelet-rich plasma (PRP) injections ...
Jia-Fong Jhang +6 more
doaj +1 more source
Upk3b is dispensable for development and integrity of urothelium and mesothelium. [PDF]
The mesothelium, the lining of the coelomic cavities, and the urothelium, the inner lining of the urinary drainage system, are highly specialized epithelia that protect the underlying tissues from mechanical stress and seal them from the overlying fluid ...
Carsten Rudat +8 more
doaj +1 more source
TUMORS OF THE UPPER UROTHELIUM [PDF]
Forty-two cases of malignant tumors of renal pelvis were reviewed: 28 were transitional cell carcinomas; and 14 were squamous cell carcinomas.The natural history and spread of the disease is discussed in detail. Transitional cell carcinomas spread primarily to the ureter (40 per cent), followed closely by the renal bed (33 per cent) and bladder (30 per
openaire +2 more sources
The urothelium of the bladder, renal pelvis, ureter and urethra is maintained through the regulated proliferation and differentiation of urothelial stem and progenitor cells.
Chi-Ping Huang +4 more
doaj +1 more source
K-Ras and β-catenin mutations cooperate with Fgfr3 mutations in mice to promote tumorigenesis in the skin and lung, but not in the bladder [PDF]
The human fibroblast growth factor receptor 3 (FGFR3) gene is frequently mutated in superficial urothelial cell carcinoma (UCC). To test the functional significance of FGFR3 activating mutations as a ‘driver’ of UCC, we targeted the expression of mutated
Taketo, M.M. +17 more
core +1 more source
The Current Use of Stem Cells in Bladder Tissue Regeneration and Bioengineering
Many pathological processes including neurogenic bladder and malignancy necessitate bladder reconstruction, which is currently performed using intestinal tissue. The use of intestinal tissue, however, subjects patients to metabolic abnormalities, bladder
Yvonne Y. Chan +3 more
doaj +1 more source
Altered expression of transmembrane mucins, MUC1 and MUC4, in bladder cancer: pathological implications in diagnosis. [PDF]
Radical changes in both expression and glycosylation pattern of transmembrane mucins have been observed in various malignancies. We and others have shown that MUC1 and MUC4, two transmembrane mucins, play a sentinel role in cell signaling events that ...
Sukhwinder Kaur +7 more
doaj +1 more source

