Results 41 to 50 of about 23,871 (225)

UPEC Colonic-Virulence and Urovirulence Are Blunted by Proanthocyanidins-Rich Cranberry Extract Microbial Metabolites in a Gut Model and a 3D Tissue-Engineered Urothelium

Microbiology Spectrum, 2022
Uropathogenic Escherichia coli (UPEC) ecology-pathophysiology from the gut reservoir to its urothelium infection site is poorly understood, resulting in equivocal benefits in the use of cranberry as prophylaxis against urinary tract infections.
Charlène Roussel, Stéphane Chabaud, Jacob Lessard-Lord, Valentina Cattero, Félix-Antoine Pellerin, Perrine Feutry, Valérie Bochard, Stéphane Bolduc, Yves Desjardins   +8 more
doaj   +1 more source

Polyploid superficial cells that maintain the urothelial barrier are produced via incomplete cytokinesis and endoreplication [PDF]

, 2018
Summary: The urothelium is an epithelia barrier lined by a luminal layer of binucleated, octoploid, superficial cells. Superficial cells are critical for production and transport of uroplakins, a family of proteins that assemble into a waterproof ...
Batourina, Ekatherina, Canman, Julie C, Dan, Hanbin, George, Christopher D, Liu, Chang, Mendelsohn, Cathy Lee, Mysorekar, Indira U, Schneider, Kerry, Souza, Spenser, Swayne, Theresa, Tate, Tiffany, Wang, Jia, Wiessner, Gregory, Zhuravlev, Yelena   +13 more
core   +3 more sources

Free ureteral replacement in rats: regeneration of ureteral wall components in the acellular matrix graft. [PDF]

, 1997
ObjectivesTo evaluate ureteral replacement by a free homologous graft of acellular matrix in a rat model.MethodsIn 30 male Sprague-Dawley rats, a 0.3 to 0.8-cm midsegment of the left ureter was resected and replaced with an acellular matrix graft of ...
Dahiya, R, Dahms, SE, Lue, TF, Nunes, L, Piechota, HJ, Tanagho, EA   +5 more
core   +1 more source

Urine-Derived Stem Cells for Epithelial Tissues Reconstruction and Wound Healing

Pharmaceutics, 2022
Epithelial tissue injury can occur on any surface site of the body, particularly in the skin or urethral mucosa tissue, due to trauma, infection, inflammation, and toxic compounds.
Xiya Yin, Qingfeng Li, Patrick Michael McNutt, Yuanyuan Zhang   +3 more
doaj   +1 more source

A Biomimetic Porcine Urothelial Model for Assessing Escherichia coli Pathogenicity

Microorganisms, 2022
Urinary tract infections can be severe, sometimes fatal, diseases whose etiological pathogens are predominantly uropathogenic strains of E. coli (UPEC).
Luka Predojević, Darja Keše, Darja Žgur Bertok, Taja Železnik Ramuta, Peter Veranič, Mateja Erdani Kreft, Marjanca Starčič Erjavec   +6 more
doaj   +1 more source

Loss of Janus Associated Kinase 1 Alters Urothelial Cell Function and Facilitates the Development of Bladder Cancer

Frontiers in Immunology, 2019
Inherited Primary Immunodeficiency (PID) disorders are associated with increased risk of malignancy that may relate to impaired antitumor immune responses or a direct role for PID germline mutations in tumorigenesis.
Vanessa Daza-Cajigal, Vanessa Daza-Cajigal, Vanessa Daza-Cajigal, Vanessa Daza-Cajigal, Vanessa Daza-Cajigal, Adriana S. Albuquerque, Joanna Pearson, Jennifer Hinley, Andrew S. Mason, Jens Stahlschmidt, Jens Stahlschmidt, Adrian J. Thrasher, Adrian J. Thrasher, Vibhash Mishra, Jennifer Southgate, Siobhan O. Burns, Siobhan O. Burns   +16 more
doaj   +1 more source

Mechanosensitive Hydrolysis of ATP and ADP in Lamina Propria of the Murine Bladder by Membrane-Bound and Soluble Nucleotidases

Frontiers in Physiology, 2022
Prior studies suggest that urothelium-released adenosine 5′-triphosphate (ATP) has a prominent role in bladder mechanotransduction. Urothelial ATP regulates the micturition cycle through activation of purinergic receptors that are expressed in many cell ...
Mafalda S. L. Aresta Branco, Alejandro Gutierrez Cruz, Jacob Dayton, Brian A. Perrino, Violeta N. Mutafova-Yambolieva   +4 more
doaj   +1 more source

Prospective study to compare antibiosis versus the association of N-acetylcysteine, D-mannose and morinda citrifolia fruit extract in preventing urinary tract infections in patients submitted to urodynamic investigation [PDF]

, 2017
BACKGROUND: The abuse of antimicrobical drugs has increased the resistance of microorganisms to treatments, thus to make urinary tract infections (UTIs) more difficult to eradicate.
Al Rawashdah, S, AL SALHI, Yazan, Carbone, Antonio, Coppola, Gianpietro, Fuschi, Andrea, Leto, Antonino, Maruccia, S, Maurizi, Angela, Mele, Rita, Palleschi, Giovanni, Pastore, ANTONIO LUIGI, Velotti, Gennaro, Zanello, Pp   +12 more
core   +2 more sources

Combined lectin- and immuno-histochemistry (CLIH) for applications in cell biology and cancer diagnosis: Analysis of human urothelial carcinomas

European Journal of Histochemistry, 2020
Lectin histochemistry (LHC) and immunohistochemistry (IHC), which demonstrate the composition and localisation of sugar residues and proteins in cell membranes, respectively, are generally used separately.
Daša Zupančič, Mateja Erdani Kreft, Igor Sterle, Rok Romih   +3 more
doaj   +1 more source

TRPA1 channel mediates methylglyoxal-induced mouse bladder dysfunction

Frontiers in Physiology, 2023
Introduction: The transient receptor potential ankyrin 1 channel (TRPA1) is expressed in urothelial cells and bladder nerve endings. Hyperglycemia in diabetic individuals induces accumulation of the highly reactive dicarbonyl compound methylglyoxal (MGO),
Akila L. Oliveira, Matheus L. Medeiros, Erick de Toledo Gomes, Glaucia Coelho Mello, Soraia Katia Pereira Costa, Fabíola Z. Mónica, Edson Antunes   +6 more
doaj   +1 more source