Results 41 to 50 of about 4,974 (168)

UCtracker: A Deep Learning–Based DNA Methylation Model for Noninvasive Diagnosis and Recurrence Surveillance of Urothelial Carcinoma in a Prospective Study

open access: yesAdvanced Science, EarlyView.
We developed UCtracker, a urine DNA methylation–based deep learning model, for noninvasive diagnosis and postoperative surveillance of urothelial carcinoma. UCtracker demonstrates high diagnostic accuracy, robustness at ultralow sequencing depth, early recurrence detection, and dynamic risk‐stratified monitoring of molecular residual disease ...
Shengwei Xiong   +19 more
wiley   +1 more source

Two case reports of mixed epithelial and stromal renal tumor of kidney in children and literature review analysis

open access: yesIndian Journal of Pathology and Microbiology, 2023
Mixed epithelial and stromal tumor of the kidney (MESTK) occurs almost exclusively in perimenopausal women while rarely in children. Only five pediatric patients have been described previously. Herein, we report a girl and a boy with MESTK, aged 3- and 4-
Xia Wei   +3 more
doaj   +1 more source

Natural‐Inspired Engineered Microalgae With Selenium Enrichment Enabled Potent Anti‐Tumor Immunity

open access: yesAdvanced Science, EarlyView.
Se‐Ssp was engineered as a potent immunomodulator for activating innate immunity via the TLR and cGAS‐STING pathways, therefore converting “cold” tumors into “hot” tumors to achieve high efficacy and long‐term therapeutic outcomes. ABSTRACT Immunotherapy has shed light on clinical oncology for several decades.
Yuqi Yang   +11 more
wiley   +1 more source

The role of urothelium in induced ossification in skeletal muscle [PDF]

open access: yes, 2006
It is a well established phenomenon that the epithelial lining of the urinary bladder (urothelium) when implanted into skeletal muscle induces ectopic ossification. However, despite numerous observations, this reaction is poorly understood.
Podagiel, Christopher
core  

Urothelium removal does not impact mucosal activity in response to muscarinic or adrenergic receptor stimulation [PDF]

open access: yes, 2022
The inner lining of the urinary bladder (urothelium and lamina propria, or bladder mucosa) has an important role as a tissue barrier between stored urine and the underlying smooth muscle, as well as in the modulation and regulation of bladder ...
Moro, Christian   +3 more
core   +1 more source

Interrelations between factors in the development of inflammatory changes in the urinary tract in the comprehensive treatment of patients with urolithiasis

open access: yesZaporožskij Medicinskij Žurnal
The aim of the work is to analyze the scientific literature data on the principles and state of rational antibiotic therapy use according to factors for the development of inflammatory changes in the urinary tract with the identification of the latter in
O. O. Lyulko, V. O. Morhuntsov
doaj   +1 more source

AARS1‐Mediated H3K27 Lactylation Rewires Glycolysis to Sustain Aggressive and Recurrent Bladder Cancer

open access: yesAdvanced Science, EarlyView.
AARS1 drives PI3K–AKT–mTOR‐dependent glycolysis in bladder cancer, promoting lactate accumulation, increased lactylation, H3K27la enrichment at the HK2 promoter, and HK2 transcription. HK2 reinforces glycolysis, sustaining a metabolic–epigenetic program associated with tumor progression, recurrence, and metastasis.
Qin Yuan   +13 more
wiley   +1 more source

Structure of aging and young mice urothelium.

open access: yes, 2013
(a) Semi-thin section of urothelium in aging mice showing normal structure of three-layered epithelium with numerous lipofuscin granules in the cytoplasm of superficial cells (arrows).
Martina Perše (4262386)   +2 more
core   +1 more source

Production of Urothelium from Pluripotent Stem Cells for Regenerative Applications [PDF]

open access: yes, 2015
As bladder reconstruction strategies evolve, a feasible and safe source of transplantable urothelium becomes a major consideration for patients with advanced bladder disease, particularly cancer. Pluripotent stem cells, such as embryonic stem cells (ESCs)
Osborn, SL   +3 more
core   +1 more source

A Bioinspired Underwater Soft Robot for Active Intravesical Liquid Delivery and Mixing

open access: yesAdvanced Intelligent Systems, EarlyView.
A bioinspired underwater soft robot is reported that integrates an elastic strain energy‐driven soft robotic pump with a programmable flexible magnetic valve, enabling remotely controlled, programmable, and sustained liquid release and mixing. This functionality is enabled by the synergistic integration of elastic strain energy‐driven pumping and ...
Jacob Katona   +7 more
wiley   +1 more source

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