Results 51 to 60 of about 4,974 (168)
The use of multispectral imaging to distinguish reactive urothelium from neoplastic urothelium
Journal of Pathology Informatics, 2010 The interpretation of urothelial atypia in a setting of chronic inflammation and reactive changes can prove difficult with small biopsies. Limited recuts lessen the efficacy of ancillary studies such as CK20, P53 and CD44 in these instances.To evaluate a triple-immunostain with the assistance of multispectral microscopy.Fifty-three bladder biopsies ...
Christopher Michael Gilbert +1 more
openaire +3 more sources
Novel TEM findings in IC/BPS urothelium.
, 2018 (A) red blood cells extravasation (black arrows) from lamina propria to urothelium with interrupted basement membrane (arrowheads, bar: 10um). This bladder specimen was obtained before hydrodistention.
Yuan-Hong Jiang (398786) +5 more
core +1 more source
Cancer Nexus, EarlyView.ABSTRACT In this study, we identified gene modules and representative candidate biomarkers linked to clinical progression in patients with UBC. Weighted gene co‐expression network analysis (WGCNA) was used to identify gene modules associated with TNM staging in UBC patients.
Arshia Azmoudeh
wiley +1 more source
Tumorigenicity of RTK/RAS in urothelium
Oncoscience, 2015 Although bladder cancer (BC) was the cancer from which the first human oncogene, RAS, was identified, questions persisted over the past 35 years as to whether RAS activation in urothelium was tumorigenic [1]. This was due in large part to the relatively low frequency (~15%) and lack of grade and stage association of RAS mutations in human BC [2 ...
Xue-Ru, Wu +2 more
openaire +2 more sources
International Journal of Cancer, EarlyView.ABSTRACT Tobacco smoking has a strong influence on DNA methylation (DNAm), enabling the development of DNAm‐based smoking predictors, yet external evaluations of these have remained limited. We aimed to assess six DNAm‐based smoking predictors in a large sample of middle‐aged and older Australians for (i) their accuracy and reliability, and (ii) their ...
Xiaoyu Fan +8 more
wiley +1 more source
Neurourology and Urodynamics, EarlyView.ABSTRACT Background & Aims Neurogenic lower urinary tract dysfunction (NLUTD) can produce bothersome urinary symptoms, impact quality of life, and in some cases, lead to deterioration of upper urinary tract function. Intradetrusor injection of onabotulinumtoxin‐A (BoNT‐A) is approved for NLUTD in patients who have an inadequate response to or ...
Shirley L. Wang +2 more
wiley +1 more source
Effects of Cyr61 and Wnt5a on urothelium growth.
, 2015 (A) Wnt5aOX resulted in mean urothelium width similar to MSC/CD34+ HSPCs. Cyr61OX resulted in urothelium width significantly greater than Cyr61KD at both time points. Cyr61KD and unseeded grafts had the thinnest urothelium.
Jessica H. Hannick (798902) +6 more
core +1 more source
International Brazilian Journal of Urology, 2009 Purpose: We investigated the presence of functional ß1, ß2 and ß3-adrenoceptor in urothelium and detrusor muscle of human bladder through in vitro pharmacology of selective ß3 adrenoceptor agonist solabegron.
Pradeep Tyagi +3 more
doaj +1 more source
Neurourology and Urodynamics, EarlyView.ABSTRACT Objective To explore molecular mechanisms underlying excessive extracellular adenosine (ADO) accumulation in the bladder lamina propria (LP) of mice with type 2 diabetes (T2D) induced by a high‐fat, high‐sucrose diet (HFHSD), conceivably leading to bladder underactivity.
Mahsa Borhani Peikani +2 more
wiley +1 more source
Understanding mechanisms of Ketamine-induced human urinary tract damage [PDF]
, 2011 Ketamine is a phencyclidine derivative N-Methyl D-Aspartate (NMDA) receptor antagonist used as an anaesthetic and analgesic. A florid non-bacterial cystitis condition known as ketamine-induced cystitis (KIC) has recently been reported in abusers and ...
Shahzad, Khurram
core +3 more sources