Results 71 to 80 of about 14,292 (181)

Reconstruction of deep and perforating corneal defects in dogs—A review (Part III/III): The use of corneal sutures and reporting of ocular discomfort

open access: yesVeterinary Ophthalmology, Volume 28, Issue 2, Page 543-552, March 2025.
Abstract The surgical reconstruction of severe corneal disease is a common and crucial component of the clinical practice of veterinary ophthalmology. The first part of the present review described procedures that utilize autogenous ocular tissues, homologous donor tissues, and heterologous donor tissues in dogs, while the second part reviewed the use ...
R. F. Sanchez
wiley   +1 more source

Update on cellular expression and function of ANO1 channels in urethral smooth muscle

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Activation of ANO1 channels and resulting Cl− efflux are suggested to modulate urethral smooth muscle contractility by enhancing Ca2+ influx via voltage‐dependent Ca2+ entry and resulting contraction in urethral smooth muscle cells.
Bernard T. Drumm, Neha Gupta
wiley   +1 more source

The Botulinum Treatment of Neurogenic Detrusor Overactivity: The Double-Face of the Neurotoxin

open access: yesToxins, 2019
Botulinum neurotoxin (BoNT) can counteract the highly frequent involuntary muscle contractions and the uncontrolled micturition events that characterize the neurogenic detrusor overactivity (NDO) due to supra-sacral spinal cord lesions.
Chiara Traini, Maria Giuliana Vannucchi
doaj   +1 more source

Intravesical therapy for recurrent urinary tract infection: a systematic review and meta‐analysis

open access: yesBJU International, Volume 138, Issue 1, Page 33-44, July 2026.
Objective To undertake a systematic review and meta‐analysis to evaluate the efficacy, safety, and clinical applicability of intravesical instillations for preventing recurrent urinary tract infections (rUTIs). Methods PubMed/MEDLINE, Embase, Cochrane CENTRAL, Scopus, and Web of Science were searched from January 2000 to April 2025 for randomised and ...
Matthew Kwon   +3 more
wiley   +1 more source

Strain-level heterogeneity in Gardnerella urinary tract persistence and pathogenesis in an in vivo model is consistent with comparative phylogenomic analyses

open access: yesBMC Microbiology
Background Gardnerella is a bacterial genera commonly present in the female urogenital tract, especially in bacterial vaginosis. Gardnerella are frequently detected in urine collected directly from the bladder and have been implicated in urinary ...
Lokesh Kumar   +4 more
doaj   +1 more source

Paclitaxel with Cisplatin as Salvage Treatment for Patients with Previously Treated Advanced Transitional Cell Carcinoma of the Urothelial Tract

open access: yesNeoplasia: An International Journal for Oncology Research, 2007
BACKGROUND: This study was performed to evaluate the safety and efficacy of paclitaxel with cisplatin as salvage therapy in patients previously treated with gemcitabine and cisplatin (G/C) for advanced transitional cell carcinoma (TCC) of the urothelial ...
Ji Eun Uhm   +7 more
doaj   +1 more source

PPARγ promotes urothelial remodeling during urinary tract obstruction

open access: yesExperimental and Molecular Medicine
Urinary tract obstruction (UTO) is a common cause of kidney injury that can result in chronic kidney disease and end-stage renal disease. Heterogeneity in the extent of obstructive renal damage in humans with UTO implies the existence of unknown ...
Mohammad El-Harakeh   +11 more
doaj   +1 more source

N–3 and n–6 polyunsaturated fatty acids induce cytostasis in human urothelial cells independent of p53 gene function

open access: yesJournal of Lipid Research, 2000
The role of long-chain polyunsaturated fatty acids (PUFA) in the etiopathology and treatment of cancer is poorly understood. We have studied the effects of n–3 and n–6 PUFA on the proliferation and survival of normal human uroepithelial (NHU) cells ...
Christine P. Diggle   +4 more
doaj   +1 more source

Phase II Study of Biweekly Plitidepsin as Second-Line Therapy for Advanced or Metastatic Transitional Cell Carcinoma of the Urothelium

open access: yesMarine Drugs, 2009
The objective of this exploratory, open-label, single-arm, phase II clinical trial was to evaluate plitidepsin (5 mg/m2) administered as a 3-hour continuous intravenous infusion every two weeks to patients with locally advanced/metastatic transitional ...
Sergio Szyldergemajn   +8 more
doaj   +1 more source

Urothelial Proteome Changes Underlying Overactive Bladder Associated With Bladder Outlet Obstruction [PDF]

open access: yesInternational Neurourology Journal
Purpose Overactive bladder (OAB) in men with bladder outlet obstruction (BOO) due to benign prostatic hyperplasia (BPH) represents a major therapeutic challenge, as symptoms often persist even after surgical relief of obstruction.
Sang-Yeop Lee   +8 more
doaj   +1 more source

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