Results 71 to 80 of about 4,974 (168)

First‐in‐human outpatient management of recurrent NMIBC with the Multi4 instrument

BJU International, EarlyView.
Objectives To evaluate the feasibility, safety and diagnostic performance of outpatient management of recurrent non‐muscle‐invasive bladder cancer (NMIBC) under local anaesthesia using the Multi4 instrument, a series of preclinical studies were performed followed by a first‐in‐human clinical investigation.
Miden Melle‐Hannah, Henrik Kjölhede, Henrik Bäckdahl, Martin E. Johansson, Joakim Håkansson   +4 more
wiley   +1 more source

Phloroglucinol inhibits human ureteral contractions via activation of cAMP‐PKA pathway

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Phloroglucinol is used to treat renal colic, especially when non‐steroidal anti‐inflammatory drugs are contraindicated. This study aimed to clarify its mechanism by examining effects on human ureteral contractility and underlying signalling pathways. Experimental Approach Urinary levels of neurokinin A (NKA), substance P
Hanwen Liu, Ruize Xu, Zihan Guan, Lei Liu, Guangda Lv, Weibo Chen, Jiliang Wen, Jianing Liu, Jieke Yan, Fangxin Gong, Pan Xiao, Xiulin Zhang, Lei Zhang   +12 more
wiley   +1 more source

Hybrid grading systems improve progression risk stratification in non‐invasive papillary urothelial carcinoma and support a histomorphological continuum of disease progression

Histopathology, EarlyView.
Hybrid grading systems significantly improve progression‐risk stratification in non‐invasive papillary urothelial carcinoma compared with the WHO 2004/2016 binary classification, with most benefit achieved by a Hybrid 3‐Tier framework. These findings support the existence of a histomorphological continuum of progression risk within the conventional ...
Jane K Nguyen, Marcello P Toscano, Jianbo Li, Sean R Williamson, Christopher G Przybycin, Chia‐Sui Kao, Jonathan L Myles, Kristýna Pivovarčíková, Marián Švajdler, Marek Brousil, Mohamed Eltemamy, Laura Bukavina, Venkatesh Krishnamurthi, Christopher Weight, Rebecca A Campbell, Nima Almassi, Reza Alaghehbandan   +16 more
wiley   +1 more source

MUC4 expression in non-neoplastic urothelium and various malignant phenotypes of bladder.

, 2014
acomparison vs. non-neoplastic urothelium.bp≤0.0001 vs. non-neoplastic urothelium.cp≤0.005 vs.
Sukhwinder Kaur (91168), Subhankar Chakraborty (230378), Adam J. Horn (543028), Subodh M. Lele (122057), David G. Wagner (543027), Dan Theodorescu (105547), Navneet Momi (543026), Surinder K. Batra (120446)   +7 more
core   +1 more source

Male genital lichen sclerosus

Journal of the European Academy of Dermatology and Venereology, EarlyView.
Male genital lichen sclerosus is driven by chronic, occluded exposure of susceptible genital epithelium to urine, rather than infection or autoimmunity. This review synthesizes clinical, anatomical and molecular evidence showing how microincontinence and occlusion initiate inflammation, fibrosis and carcinogenesis, and explains the curative effect of ...
Georgios Kravvas, Rory Barry, Richard E. Watchorn, Christopher B. Bunker   +3 more
wiley   +1 more source

MUC1 expression in non-neoplastic urothelium and various malignant phenotypes of bladder.

, 2014
acomparison vs. non-neoplastic urothelium.bp≤0.0001 vs. non-neoplastic urothelium.cp≤0.005 vs.
Sukhwinder Kaur (91168), Subhankar Chakraborty (230378), Adam J. Horn (543028), Subodh M. Lele (122057), David G. Wagner (543027), Dan Theodorescu (105547), Navneet Momi (543026), Surinder K. Batra (120446)   +7 more
core   +1 more source

Strain-level heterogeneity in Gardnerella urinary tract persistence and pathogenesis in an in vivo model is consistent with comparative phylogenomic analyses

BMC Microbiology
Background Gardnerella is a bacterial genera commonly present in the female urogenital tract, especially in bacterial vaginosis. Gardnerella are frequently detected in urine collected directly from the bladder and have been implicated in urinary ...
Lokesh Kumar, Sonia N. Whang, Deborah K. Verges, Robert F. Potter, Nicole M. Gilbert   +4 more
doaj   +1 more source

Lower density of calretinin‐immunopositive neurons in the putamen of subjects with schizophrenia

Journal of Anatomy, Volume 246, Issue 4, Page 505-516, April 2025.
Recent neuroimaging and histological studies highlight the striatum as a key area involved in SCH, but the specific impairment of neuronal subtypes in subcortical structures is not fully understood. This study is the first detailed investigation of neuroanatomical changes in the putamen in SCH, specifically examining the density of calretinin ...
Paz Kelmer, Paulina Hoppa, Erzsébet Frank, Teadora Tyler, Istvan Adorjan   +4 more
wiley   +1 more source

Spatial transcriptomic map of the mouse urinary bladder

Scientific Reports
We present a spatial transcriptomic map of the mouse urinary bladder at near single-cell resolution using Visium HD technology with 8 × 8 μm bins. After quality filtering, we analyzed 66,471 bins and 9,364 genes.
Nives Matković, Andrea Gelemanović, Kristijana Popović, Katarina Vilović, Caterina Oneto, Dejan Lazarević, Ivana Marinović Terzić, Ivana Novak, Jelena Korac-Prlic, Blanka Milić Roje, Janoš Terzić   +10 more
doaj   +1 more source

Reconstruction of deep and perforating corneal defects in dogs—A review (Part III/III): The use of corneal sutures and reporting of ocular discomfort

Veterinary Ophthalmology, Volume 28, Issue 2, Page 543-552, March 2025.
Abstract The surgical reconstruction of severe corneal disease is a common and crucial component of the clinical practice of veterinary ophthalmology. The first part of the present review described procedures that utilize autogenous ocular tissues, homologous donor tissues, and heterologous donor tissues in dogs, while the second part reviewed the use ...
R. F. Sanchez
wiley   +1 more source