Results 71 to 80 of about 23,871 (225)
The Expression and Regulation of Chemokines (CXCL9, CXCL10, CXCL11) in Urinary Bladder Inflammation of the Mouse [PDF]
, 2017 Interstitial cystitis is a serious chronic condition that causes bladder pain and increased voiding frequency in millions of adults in the US, most of them women.
Guo, Michael
core +1 more source
Intravesical therapy for recurrent urinary tract infection: a systematic review and meta‐analysis
BJU International, EarlyView.Objective To undertake a systematic review and meta‐analysis to evaluate the efficacy, safety, and clinical applicability of intravesical instillations for preventing recurrent urinary tract infections (rUTIs). Methods PubMed/MEDLINE, Embase, Cochrane CENTRAL, Scopus, and Web of Science were searched from January 2000 to April 2025 for randomised and ...
Matthew Kwon +3 more
wiley +1 more source
FGF7 peptide (FGF7p) mimetic mitigates bladder urothelial injury from cyclophosphamide
Physiological Reports, 2022 Although full‐length fibroblast growth factor 7 (FGF7) blocks cyclophosphamide‐induced urothelial apoptosis in mice, limitations include high production costs because of its large size.
Sridhar Tatarao Narla +8 more
doaj +1 more source
Tumorigenicity of RTK/RAS in urothelium
Oncoscience, 2015 Although bladder cancer (BC) was the cancer from which the first human oncogene, RAS, was identified, questions persisted over the past 35 years as to whether RAS activation in urothelium was tumorigenic [1]. This was due in large part to the relatively low frequency (~15%) and lack of grade and stage association of RAS mutations in human BC [2 ...
Xue-Ru, Wu +2 more
openaire +2 more sources
BJU International, EarlyView.Objectives To evaluate the feasibility of ex vivo fluorescence confocal microscopy (FCM) for real‐time assessment of ureteroscopic biopsy specimen adequacy in patients with suspected upper tract urothelial carcinoma (UTUC). Patients and Methods In this prospective, single‐centre feasibility study, four ureteroscopic biopsy specimens obtained from two ...
Karim Daher +14 more
wiley +1 more source
Urothelial Senescence in the Pathophysiology of Diabetic Bladder Dysfunction—A Novel Hypothesis
Frontiers in Surgery, 2018 Diabetic bladder dysfunction (DBD) is a well-recognized and common symptom affecting up to 50% of all diabetic patients. DBD has a broad range of clinical presentations ranging from overactive to underactive bladder symptoms that develops in middle-aged ...
Nicole S. Klee +6 more
doaj +1 more source
Regional biomechanical and histological characterisation of the passive porcine urinary bladder: Implications for augmentation and tissue engineering strategies [PDF]
, 2009 The aim of this study was to identify and quantify potential regional and directional variations in the quasistatic uniaxial mechanical properties of the passive urinary bladder wall.
Bolland, Fiona +4 more
core +1 more source
British Journal of Pharmacology, EarlyView.Abstract Catecholamines are classically viewed as neuronal transmitters and adrenal hormones; however, accumulating evidence demonstrates that sources other than nerve fibres and adrenal medulla play a fundamental role in local organ regulation. Physiological paradoxes, such as preserved organ function after denervation or transplantation, challenge a ...
Mariana G. de Oliveira +3 more
wiley +1 more source
Down-regulation of myopodin expression reduces invasion and motility of PC-3 prostate cancer cells [PDF]
, 2009 Enhanced motility of cancer cells by remodelling of the actin cytoskeleton is crucial in the process of cancer cell invasion and metastasis. Although several studies propose a tumor suppressor role for the actin bundling protein myopodin, it was also ...
Bracke, Marc +5 more
core +1 more source
Histopathology, EarlyView.FOXA1 is a highly sensitive diagnostic marker for prostate cancer. Besides prostatic adenocarcinoma, it is also expressed in 57%–80% of metastatic or primary prostatic small cell carcinomas, which lose traditional prostatic markers including NKX3.1. Although it is less specific than NKX3.1, it can serve as a valuable adjunct for confirming prostatic ...
Jianping Zhao +11 more
wiley +1 more source