Results 61 to 70 of about 4,974 (168)
For augmentation or reconstruction of urinary bladder after cystectomy, bladder urothelium derived from human induced pluripotent stem cells (hiPSCs) has recently received focus. However, previous studies have only shown the emergence of cells expressing
Kotaro Suzuki +5 more
doaj +1 more source
ABSTRACT Purpose To investigate the adenosine receptor (AR) mechanism underlying bladder outlet obstruction (BOO)‐related bladder dysfunction, we examined the expression level of AR subtypes in bladder tissues, and the effects of AR subtypes A2B & A3 modulation on bladder activity using male BOO rats, and Dahl rats with A2B receptor deletion. Materials
Masahiro Kurobe +8 more
wiley +1 more source
We assessed the prognostic factors on recurrence and disease-specific survival of patients treated for upper tract transitional cell carcinoma (TCC).
Keng Siang Png +5 more
doaj +1 more source
ABSTRACT Background For prostate cancer (PCa), early diagnosis and biomarker‐based patient stratification can improve clinical decision‐making and post‐treatment prognosis. PCa biomarkers are best validated in tissue following comprehensive histopathologic review; however, urinary biomarkers can be obtained non‐invasively and are therefore safer and ...
Yuandong Xing +11 more
wiley +1 more source
ABSTRACT Green tea catechins have chemopreventive potential; however, the clinical evidence remains inconsistent. This review evaluated the effects of supplementation with green tea derivatives on chemoprevention at different stages of carcinogenesis. PubMed, Embase, Web of Science, Scopus, the Cochrane Library, CINAHL, and Google Scholar were searched
Thaís Moreira Machado +6 more
wiley +1 more source
FGF7 peptide (FGF7p) mimetic mitigates bladder urothelial injury from cyclophosphamide
Although full‐length fibroblast growth factor 7 (FGF7) blocks cyclophosphamide‐induced urothelial apoptosis in mice, limitations include high production costs because of its large size.
Sridhar Tatarao Narla +8 more
doaj +1 more source
ABSTRACT Image‐guided thermal ablation (radiofrequency, cryo‐ and microwave ablation) is a safe and effective primary treatment for small renal mass and localised renal cell carcinoma ≤ 4 cm (T1a) with long‐term cancer‐specific survival rates equivalent to surgical resection (Level A).
Matthew Lukies +6 more
wiley +1 more source
Urothelial Senescence in the Pathophysiology of Diabetic Bladder Dysfunction—A Novel Hypothesis
Diabetic bladder dysfunction (DBD) is a well-recognized and common symptom affecting up to 50% of all diabetic patients. DBD has a broad range of clinical presentations ranging from overactive to underactive bladder symptoms that develops in middle-aged ...
Nicole S. Klee +6 more
doaj +1 more source
Androgen Receptor Expression in Urothelial Bladder Cancer—A Systematic Review and Meta‐Analysis
ABSTRACT Background Bladder cancer is a globally prevalent malignancy with a marked male predominance. Over the past decade, the androgen receptor has been investigated as a potential contributor to bladder cancer pathophysiology. Androgen receptor expression is most commonly assessed via immunohistochemistry, but its association with pathological ...
Alex Buckby +3 more
wiley +1 more source
Induction of Human Embryonic and Induced Pluripotent Stem Cells Into Urothelium [PDF]
In vitro generation of human urothelium from stem cells would be a major advancement in the regenerative medicine field, providing alternate nonurologic and/or nonautologous tissue sources for bladder grafts.
Thangappan, Ravikumar +5 more
core +1 more source

