Results 61 to 70 of about 4,974 (168)

Directed differentiation of human induced pluripotent stem cells into mature stratified bladder urothelium

open access: yesScientific Reports, 2019
For augmentation or reconstruction of urinary bladder after cystectomy, bladder urothelium derived from human induced pluripotent stem cells (hiPSCs) has recently received focus. However, previous studies have only shown the emergence of cells expressing
Kotaro Suzuki   +5 more
doaj   +1 more source

Functional Roles of Adenosine A2B and A3 Receptor Subtypes in the Bladder of Male Rats With A2B Receptor Deletion or Bladder Outlet Obstruction

open access: yesNeurourology and Urodynamics, EarlyView.
ABSTRACT Purpose To investigate the adenosine receptor (AR) mechanism underlying bladder outlet obstruction (BOO)‐related bladder dysfunction, we examined the expression level of AR subtypes in bladder tissues, and the effects of AR subtypes A2B & A3 modulation on bladder activity using male BOO rats, and Dahl rats with A2B receptor deletion. Materials
Masahiro Kurobe   +8 more
wiley   +1 more source

Prognostic Factors for Upper Tract Transitional Cell Carcinoma: A Retrospective Review of 66 Patients

open access: yesAsian Journal of Surgery, 2008
We assessed the prognostic factors on recurrence and disease-specific survival of patients treated for upper tract transitional cell carcinoma (TCC).
Keng Siang Png   +5 more
doaj   +1 more source

Comparison of Gene Enrichment Between Prostate Tissue and Urine for Non‐Invasive Biomarker Development

open access: yesThe Prostate, EarlyView.
ABSTRACT Background For prostate cancer (PCa), early diagnosis and biomarker‐based patient stratification can improve clinical decision‐making and post‐treatment prognosis. PCa biomarkers are best validated in tissue following comprehensive histopathologic review; however, urinary biomarkers can be obtained non‐invasively and are therefore safer and ...
Yuandong Xing   +11 more
wiley   +1 more source

Effects of Green Tea Supplementation on Chemoprevention at Different Stages of Carcinogenesis: A Systematic Review

open access: yesPhytotherapy Research, EarlyView.
ABSTRACT Green tea catechins have chemopreventive potential; however, the clinical evidence remains inconsistent. This review evaluated the effects of supplementation with green tea derivatives on chemoprevention at different stages of carcinogenesis. PubMed, Embase, Web of Science, Scopus, the Cochrane Library, CINAHL, and Google Scholar were searched
Thaís Moreira Machado   +6 more
wiley   +1 more source

FGF7 peptide (FGF7p) mimetic mitigates bladder urothelial injury from cyclophosphamide

open access: yesPhysiological Reports, 2022
Although full‐length fibroblast growth factor 7 (FGF7) blocks cyclophosphamide‐induced urothelial apoptosis in mice, limitations include high production costs because of its large size.
Sridhar Tatarao Narla   +8 more
doaj   +1 more source

Interventional Radiology Society of Australasia Quality Care Guidelines for Renal Tumour Ablation in Australia and New Zealand

open access: yesJournal of Medical Imaging and Radiation Oncology, EarlyView.
ABSTRACT Image‐guided thermal ablation (radiofrequency, cryo‐ and microwave ablation) is a safe and effective primary treatment for small renal mass and localised renal cell carcinoma ≤ 4 cm (T1a) with long‐term cancer‐specific survival rates equivalent to surgical resection (Level A).
Matthew Lukies   +6 more
wiley   +1 more source

Urothelial Senescence in the Pathophysiology of Diabetic Bladder Dysfunction—A Novel Hypothesis

open access: yesFrontiers in Surgery, 2018
Diabetic bladder dysfunction (DBD) is a well-recognized and common symptom affecting up to 50% of all diabetic patients. DBD has a broad range of clinical presentations ranging from overactive to underactive bladder symptoms that develops in middle-aged ...
Nicole S. Klee   +6 more
doaj   +1 more source

Androgen Receptor Expression in Urothelial Bladder Cancer—A Systematic Review and Meta‐Analysis

open access: yesANZ Journal of Surgery, EarlyView.
ABSTRACT Background Bladder cancer is a globally prevalent malignancy with a marked male predominance. Over the past decade, the androgen receptor has been investigated as a potential contributor to bladder cancer pathophysiology. Androgen receptor expression is most commonly assessed via immunohistochemistry, but its association with pathological ...
Alex Buckby   +3 more
wiley   +1 more source

Induction of Human Embryonic and Induced Pluripotent Stem Cells Into Urothelium [PDF]

open access: yes, 2014
In vitro generation of human urothelium from stem cells would be a major advancement in the regenerative medicine field, providing alternate nonurologic and/or nonautologous tissue sources for bladder grafts.
Thangappan, Ravikumar   +5 more
core   +1 more source

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