Results 1 to 10 of about 160,172 (303)
Suppression of lusitropy as a disease mechanism in cardiomyopathies
Frontiers in Cardiovascular Medicine, 2023 In cardiac muscle the action of adrenaline on β1 receptors of heart muscle cells is essential to adjust cardiac output to the body’s needs. Adrenergic activation leads to enhanced contractility (inotropy), faster heart rate (chronotropy) and faster ...
Steven Marston, Jose Renato Pinto
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Child’s heart development and contractility from prenatal to postnatal period
Российский кардиологический журнал, 2022 This literature review analyzes current data on the main stages of child’s heart contractility development from prenatal to postnatal period. The presented information will expand the conventional ideas on the age-related cardiovascular physiology in ...
E. N. Pavlyukova +4 more
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Current Biology, 2003 What is it? The contractile ring is a ring-shaped structure located just beneath the plasma membrane at the future division site in many, though not all, eukaryotic cell types. Composed of actin, myosin and many other proteins, it assembles in anaphase and contracts as cells divide. The contractile ring is responsible for cytokinesis in many eukaryotic
Chang, Fred, Burgess, David
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Long Prehensile Protrusions Can Facilitate Cancer Cell Invasion through the Basement Membrane
Cells, 2023 A basic process in cancer is the breaching of basement-membrane barriers to permit tissue invasion. Cancer cells can use proteases and physical mechanisms to produce initial holes in basement membranes, but how cells squeeze through this barrier into ...
Shayan S. Nazari +3 more
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A novel method to extend viability and functionality of living heart slices
Frontiers in Cardiovascular Medicine, 2023 Living heart slices have recently emerged as a powerful experimental model for fundamental cardiac research. By retaining the structure and function of the native myocardium while maintaining the simplicity of cell culture models, heart slices can be ...
Abigail J. Ross +6 more
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Frontiers in Cell and Developmental Biology, 2022 Multiple parallels exist between placentation and cancer dissemination at molecular, cellular, and anatomical levels, presenting placentation as a unique model to mechanistically understand the onset of cancer metastasis.
Junaid Afzal +10 more
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Frontiers in Physiology, 2020 Length-dependent activation of calcium-dependent myocardial force generation provides the basis for the Frank-Starling mechanism. To directly compare the effects of mutations associated with hypertrophic cardiomyopathy and dilated cardiomyopathy, the ...
Marcel Groen +4 more
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Experimental Physiology, 2023 The role of C‐type natriuretic peptide (CNP) in the regulation of cardiac function in humans remains to be established as previous investigations have been confined to animal model systems.
Julian C. Bachmann +11 more
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Contractility in an extensile system [PDF]
Soft Matter, 2017 Essentially all biology is active and dynamic. Biological entities autonomously sense, com- pute, and respond using energy-coupled ratchets that can produce force and do work. The cytoskeleton, along with its associated proteins and motors, is a canonical example of biological active matter, which is responsible for cargo transport, cell motility ...
Kasimira T. Stanhope +3 more
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eLife, 2021 A monolayer of highly motile cells can establish long-range orientational order, which can be explained by hydrodynamic theory of active gels and fluids.
Tianfa Xie +5 more
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