Results 1 to 10 of about 103,439 (265)
Congenital heart disease (CHD) is often associated with myogenic defects. During heart development, cardiomyocyte growth requires essential cues from extrinsic factors such as insulin-like growth factor 2 (IGF-2).
Maren Beall, Deqiang Li, Jihyun Jang
doaj +1 more source
Pten Regulates Cardiomyocyte Differentiation by Modulating Non‐CG Methylation via Dnmt3
The regulation of cardiomyocyte differentiation is a fundamental aspect of cardiac development and regenerative medicine. PTEN plays important roles during embryonic development. However, its role in cardiomyocyte differentiation remains unknown. In this
Wuming Wang +11 more
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Berberine protects cardiac cells against ferroptosis
Objectives: Cardiovascular diseases are one of the primary causes of death. Cardiomyocyte loss is a significant feature of cardiac injury. Ferroptosis is iron-dependent cell death, which occurs due to excess iron and reactive oxygen species (ROS ...
Kun-Ta Yang +6 more
doaj +1 more source
The IgCAM coxsackie–adenovirus receptor (CAR) is essential for embryonic heart development and electrical conduction in the mature heart. However, it is not well-understood how CAR exerts these effects at the cellular level.
Claudia Matthaeus +3 more
doaj +1 more source
Pathogenic Roles of Cardiac Fibroblasts in Pediatric Dilated Cardiomyopathy
Background Dilated cardiomyopathy (DCM) is a major cause of heart failure in children. Despite intensive genetic analyses, pathogenic gene variants have not been identified in most patients with DCM, which suggests that cardiomyocytes are not solely ...
Hirofumi Tsuru +16 more
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Cardiac lipotoxicity is an important contributor to cardiovascular complications during obesity. Given the fundamental role of the endoplasmic reticulum (ER)-resident Selenoprotein T (SELENOT) for cardiomyocyte differentiation and protection and for the ...
Carmine Rocca +19 more
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Cardiomyocyte-Imaging-Analysis/ContractQuant:
Contractile quantification of 2D stem cell derived cardiac muscle ...
Cardiomyocyte-Imaging-Analysis
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Aim: To systematically classify the profile of the RNA m6A modification landscape of neonatal heart regeneration.Materials and Methods: Cardiomyocyte proliferation markers were detected via immunostaining.
Chuanxi Yang +7 more
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Cardiomyocyte-Driven Structural Color Actuation in Anisotropic Inverse Opals
Biohybrid actuators composed of living tissues and artificial materials have attracted increasing interest in recent years because of their extraordinary function of dynamically sensing and interacting with complex bioelectrical signals. Here, a compound
Zhuoyue Chen (1459528) +7 more
core +3 more sources
DJ-1 Deficiency Protects against Sepsis-Induced Myocardial Depression
Oxidative stress is considered one of the early underlying contributors of sepsis-induced myocardial depression. DJ-1, also known as PARK7, has a well-established role as an antioxidant.
James N. Tsoporis +16 more
doaj +1 more source

