Results 1 to 10 of about 122,589 (165)

Luteolin Alleviates Axitinib-Induced Cardiomyocyte Apoptosis in Mice. [PDF]

J Biochem Mol Toxicol
Ji SW, Li X, Tang D, Bai L, Yu CL, Niu N.   +5 more
europepmc   +3 more sources

Ptbp1 Condensates With Phase Separation-Like Features in Cardiomyocyte Nuclei Regulate Splicing of Proliferative Genes in Neonatal Cardiomyocytes. [PDF]

Dev Growth Differ
Sada T, Sakaguchi A, Shinkai Y, Nakagawa R, Tanegashima C, Kadota M, Kondo T, Kimura W.   +7 more
europepmc   +2 more sources

Plant-Derived Polyphenol Salvianolic Acid B Attenuates Cardiomyocyte Pyroptosis by Modulating the MMP12-NLRP3 Signaling Axis. [PDF]

Food Sci Nutr
Xie Z, Yang ZK, Zheng L, Wu P, Chen S, Ye X, Gao Y.   +6 more
europepmc   +3 more sources

Mapping a genome-scale in vivo knockout screen to a mechanistic network model identifies VAV2, RASA1, and LEPR as regulators of cardiomyocyte hypertrophy [PDF]

bioRxiv
Lionel D. Watkins, Jeffrey J. Saucerman
europepmc   +3 more sources

CMAC: A deep learning framework for absolute cardiomyocyte transcriptional age estimation [PDF]

bioRxiv
Kwaku K. Quansah, Nadine Zureick, Elaine Chen, Sean Murphy, Emma Anderson, Esther Kwon, David Suh, Genevieve Stein-O’Brien, Patrick Cahan, Chulan Kwon   +9 more
europepmc   +3 more sources

Isolation of Embryonic Cardiomyocytes and Cell Proliferation Assay Using Genetically Engineered Reporter Mouse Model

Bio-Protocol, 2023
Congenital heart disease (CHD) is often associated with myogenic defects. During heart development, cardiomyocyte growth requires essential cues from extrinsic factors such as insulin-like growth factor 2 (IGF-2).
Maren Beall, Deqiang Li, Jihyun Jang
doaj   +1 more source

Pten Regulates Cardiomyocyte Differentiation by Modulating Non‐CG Methylation via Dnmt3

Advanced Science, 2021
The regulation of cardiomyocyte differentiation is a fundamental aspect of cardiac development and regenerative medicine. PTEN plays important roles during embryonic development. However, its role in cardiomyocyte differentiation remains unknown. In this
Wuming Wang, Gang Lu, Hong‐Bin Liu, Zhiqiang Xiong, Ho‐Duen Leung, Ruican Cao, Alan Lap‐Yin Pang, Xianwei Su, Patrick Wai Nok Law, Zhiju Zhao, Zi‐Jiang Chen, Wai‐Yee Chan   +11 more
doaj   +1 more source

Berberine protects cardiac cells against ferroptosis

Tzu Chi Medical Journal, 2022
Objectives: Cardiovascular diseases are one of the primary causes of death. Cardiomyocyte loss is a significant feature of cardiac injury. Ferroptosis is iron-dependent cell death, which occurs due to excess iron and reactive oxygen species (ROS ...
Kun-Ta Yang, Tung-Hui Chao, I-Chieh Wang, Yu-Po Luo, Pei-Ching Ting, Jian-Hong Lin, Jui-Chih Chang   +6 more
doaj   +1 more source

The IgCAM CAR Regulates Gap Junction-Mediated Coupling on Embryonic Cardiomyocytes and Affects Their Beating Frequency

Life, 2022
The IgCAM coxsackie–adenovirus receptor (CAR) is essential for embryonic heart development and electrical conduction in the mature heart. However, it is not well-understood how CAR exerts these effects at the cellular level.
Claudia Matthaeus, René Jüttner, Michael Gotthardt, Fritz G. Rathjen   +3 more
doaj   +1 more source

Pathogenic Roles of Cardiac Fibroblasts in Pediatric Dilated Cardiomyopathy

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2023
Background Dilated cardiomyopathy (DCM) is a major cause of heart failure in children. Despite intensive genetic analyses, pathogenic gene variants have not been identified in most patients with DCM, which suggests that cardiomyocytes are not solely ...
Hirofumi Tsuru, Chika Yoshihara, Hidehiro Suginobe, Mizuki Matsumoto, Yoichiro Ishii, Jun Narita, Ryo Ishii, Renjie Wang, Atsuko Ueyama, Kazutoshi Ueda, Masaki Hirose, Kazuhisa Hashimoto, Hiroki Nagano, Ryosuke Tanaka, Takaharu Okajima, Keiichi Ozono, Hidekazu Ishida   +16 more
doaj   +1 more source