Results 11 to 20 of about 146,196 (353)
Cardiomyocyte Regeneration [PDF]
The heart was initially believed to be a terminally differentiated organ; once the cardiomyocytes died, no recovery could be made to replace the dead cells. However, around a decade ago, the concept of cardiac stem cells (CSCs) in adult hearts was proposed. CSCs differentiate into cardiomyocytes, keeping the heart functioning.
Toshio Nakanishi, Nanako Kawaguchi
openaire +4 more sources
Periostin-CCL3 Feedforward Signaling Loop Promotes Cardiac Fibrosis and Cardiomyocyte Necroptosis in Arrhythmogenic Cardiomyopathy. [PDF]
POSTN‐CCL3 signaling forms a feed‐forward circuit between cardiomyocytes and cardiac myofibroblasts in arrhythmogenic cardiomyopathy. POSTN activates JNK/RIP3‐dependent necroptotic signaling and JNK/ETS2‐induced CCL3 expression in cardiomyocytes. In turn, CCL3‐CCR5 signaling in cardiac myofibroblasts activates NF‐κB/p65 and promotes POSTN expression ...
Wu T +12 more
europepmc +2 more sources
Cardiomyocyte-Imaging-Analysis/ContractQuant:
Contractile quantification of 2D stem cell derived cardiac muscle ...
Cardiomyocyte-Imaging-Analysis
core +1 more source
Cardiac lipotoxicity is an important contributor to cardiovascular complications during obesity. Given the fundamental role of the endoplasmic reticulum (ER)-resident Selenoprotein T (SELENOT) for cardiomyocyte differentiation and protection and for the ...
Carmine Rocca +19 more
doaj +1 more source
Requirements for human cardiomyocytes [PDF]
Abstract‘Requirements for human cardiomyocytes', jointly drafted and agreed upon by experts from the Chinese Society for Stem Cell Research, is the first guideline for human cardiomyocytes in China. This standard specifies the technical requirements, test methods, test regulations, instructions for use, labelling requirements, packing requirements ...
Miao Yu +26 more
openaire +2 more sources
Cardiomyocyte-Driven Structural Color Actuation in Anisotropic Inverse Opals
Biohybrid actuators composed of living tissues and artificial materials have attracted increasing interest in recent years because of their extraordinary function of dynamically sensing and interacting with complex bioelectrical signals. Here, a compound
Zhuoyue Chen (1459528) +7 more
core +3 more sources
Aim: To systematically classify the profile of the RNA m6A modification landscape of neonatal heart regeneration.Materials and Methods: Cardiomyocyte proliferation markers were detected via immunostaining.
Chuanxi Yang +7 more
doaj +1 more source
The Formin FHOD1 in Cardiomyocytes [PDF]
ABSTRACTMembers of the formin family are known to be involved in the regulation of the actin cytoskeleton. We have recently identified a muscle specific splice variant of the formin FHOD3 and demonstrated its role in the maintenance of the contractile filaments of cardiomyocytes.
Dwyer, J +4 more
openaire +3 more sources
Dyadic Plasticity in Cardiomyocytes [PDF]
Contraction of cardiomyocytes is dependent on sub-cellular structures called dyads, where invaginations of the surface membrane (t-tubules) form functional junctions with the sarcoplasmic reticulum (SR). Within each dyad, Ca2+ entry through t-tubular L-type Ca2+ channels (LTCCs) elicits Ca2+ release from closely apposed Ryanodine Receptors (RyRs) in ...
Peter P. Jones +5 more
openaire +6 more sources
DJ-1 Deficiency Protects against Sepsis-Induced Myocardial Depression
Oxidative stress is considered one of the early underlying contributors of sepsis-induced myocardial depression. DJ-1, also known as PARK7, has a well-established role as an antioxidant.
James N. Tsoporis +16 more
doaj +1 more source

