Results 11 to 20 of about 85,199 (269)
Cardiomyocyte Regeneration [PDF]
Cells, 2013 The heart was initially believed to be a terminally differentiated organ; once the cardiomyocytes died, no recovery could be made to replace the dead cells. However, around a decade ago, the concept of cardiac stem cells (CSCs) in adult hearts was proposed. CSCs differentiate into cardiomyocytes, keeping the heart functioning.
Toshio Nakanishi, Nanako Kawaguchi
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The Formin FHOD1 in Cardiomyocytes [PDF]
The Anatomical Record, 2014 ABSTRACTMembers of the formin family are known to be involved in the regulation of the actin cytoskeleton. We have recently identified a muscle specific splice variant of the formin FHOD3 and demonstrated its role in the maintenance of the contractile filaments of cardiomyocytes.
Dwyer, J +4 more
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Dyadic Plasticity in Cardiomyocytes [PDF]
Frontiers in Physiology, 2018 Contraction of cardiomyocytes is dependent on sub-cellular structures called dyads, where invaginations of the surface membrane (t-tubules) form functional junctions with the sarcoplasmic reticulum (SR). Within each dyad, Ca2+ entry through t-tubular L-type Ca2+ channels (LTCCs) elicits Ca2+ release from closely apposed Ryanodine Receptors (RyRs) in ...
Peter P. Jones +5 more
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No functional TRPA1 in cardiomyocytes [PDF]
Acta Physiologica, 2021 AbstractAimThere is mounting evidence that TRPA1 has a role in cardiac physiology and pathophysiology. We aim to clarify the site of TRPA1 expression in the heart and in particular whether the channel is expressed in cardiomyocytes.MethodsDue to the high calcium conductance of TRPA1, and marginal calcium changes being detectable, microfluorimetry in ...
Clara Hoebart +9 more
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Requirements for human cardiomyocytes [PDF]
Cell Proliferation, 2021 Abstract‘Requirements for human cardiomyocytes', jointly drafted and agreed upon by experts from the Chinese Society for Stem Cell Research, is the first guideline for human cardiomyocytes in China. This standard specifies the technical requirements, test methods, test regulations, instructions for use, labelling requirements, packing requirements ...
Miao Yu +26 more
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Cardiomyocyte Regeneration [PDF]
Circulation, 2017 Consensus ...
Eschenhagen, T +18 more
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Physiological Reports, 2023 Titin‐dependent stiffening of cardiomyocytes is a significant contributor to left ventricular (LV) diastolic dysfunction in heart failure with preserved LV ejection fraction (HFpEF).
Mark T. Waddingham +12 more
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FBPase is in the nuclei of cardiomyocytes [PDF]
FEBS Letters, 2003 Intracellular localization of FBPase in the cardiac muscle of the pig was studied by immunohistochemistry. In contrast to data from skeletal muscle [Gizak, A., Rakus, D. and Dzugaj, A. (2003) Histol. Histopathol. 18, 135–142], in cardiomyocytes FBPase was present not only in the cytoplasm, but surprisingly, also in the nucleus.
Gizak, A, Dzugaj, A
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Nucleus Mechanosensing in Cardiomyocytes
International Journal of Molecular Sciences, 2023 Cardiac muscle contraction is distinct from the contraction of other muscle types. The heart continuously undergoes contraction–relaxation cycles throughout an animal’s lifespan. It must respond to constantly varying physical and energetic burdens over the short term on a beat-to-beat basis and relies on different mechanisms over the long term.
Isabella Leite Coscarella +5 more
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Differentiation of cardiomyocyte.
Folia Pharmacologica Japonica, 2000 In the recent decade, remarkable progress has been made in the field of cardiac development through the use of molecular, biological and genetic techniques. Several genes that regulate this process have been cloned, and their functions have been analyzed in vivo and in vitro.
OKA, Toru, KOMURO, Issei
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