Results 11 to 20 of about 146,196 (353)

Cardiomyocyte Regeneration [PDF]

open access: yesCells, 2013
The heart was initially believed to be a terminally differentiated organ; once the cardiomyocytes died, no recovery could be made to replace the dead cells. However, around a decade ago, the concept of cardiac stem cells (CSCs) in adult hearts was proposed. CSCs differentiate into cardiomyocytes, keeping the heart functioning.
Toshio Nakanishi, Nanako Kawaguchi
openaire   +4 more sources

Periostin-CCL3 Feedforward Signaling Loop Promotes Cardiac Fibrosis and Cardiomyocyte Necroptosis in Arrhythmogenic Cardiomyopathy. [PDF]

open access: yesAdv Sci (Weinh)
POSTN‐CCL3 signaling forms a feed‐forward circuit between cardiomyocytes and cardiac myofibroblasts in arrhythmogenic cardiomyopathy. POSTN activates JNK/RIP3‐dependent necroptotic signaling and JNK/ETS2‐induced CCL3 expression in cardiomyocytes. In turn, CCL3‐CCR5 signaling in cardiac myofibroblasts activates NF‐κB/p65 and promotes POSTN expression ...
Wu T   +12 more
europepmc   +2 more sources

Cardiomyocyte-Imaging-Analysis/ContractQuant:

open access: yes, 2021
Contractile quantification of 2D stem cell derived cardiac muscle ...
Cardiomyocyte-Imaging-Analysis
core   +1 more source

Palmitate-Induced Cardiac Lipotoxicity Is Relieved by the Redox-Active Motif of SELENOT through Improving Mitochondrial Function and Regulating Metabolic State

open access: yesCells, 2023
Cardiac lipotoxicity is an important contributor to cardiovascular complications during obesity. Given the fundamental role of the endoplasmic reticulum (ER)-resident Selenoprotein T (SELENOT) for cardiomyocyte differentiation and protection and for the ...
Carmine Rocca   +19 more
doaj   +1 more source

Requirements for human cardiomyocytes [PDF]

open access: yesCell Proliferation, 2021
Abstract‘Requirements for human cardiomyocytes', jointly drafted and agreed upon by experts from the Chinese Society for Stem Cell Research, is the first guideline for human cardiomyocytes in China. This standard specifies the technical requirements, test methods, test regulations, instructions for use, labelling requirements, packing requirements ...
Miao Yu   +26 more
openaire   +2 more sources

Cardiomyocyte-Driven Structural Color Actuation in Anisotropic Inverse Opals

open access: yes, 2018
Biohybrid actuators composed of living tissues and artificial materials have attracted increasing interest in recent years because of their extraordinary function of dynamically sensing and interacting with complex bioelectrical signals. Here, a compound
Zhuoyue Chen (1459528)   +7 more
core   +3 more sources

Comprehensive Analysis of the Transcriptome-Wide m6A Methylome of Heart via MeRIP After Birth: Day 0 vs. Day 7

open access: yesFrontiers in Cardiovascular Medicine, 2021
Aim: To systematically classify the profile of the RNA m6A modification landscape of neonatal heart regeneration.Materials and Methods: Cardiomyocyte proliferation markers were detected via immunostaining.
Chuanxi Yang   +7 more
doaj   +1 more source

The Formin FHOD1 in Cardiomyocytes [PDF]

open access: yesThe Anatomical Record, 2014
ABSTRACTMembers of the formin family are known to be involved in the regulation of the actin cytoskeleton. We have recently identified a muscle specific splice variant of the formin FHOD3 and demonstrated its role in the maintenance of the contractile filaments of cardiomyocytes.
Dwyer, J   +4 more
openaire   +3 more sources

Dyadic Plasticity in Cardiomyocytes [PDF]

open access: yesFrontiers in Physiology, 2018
Contraction of cardiomyocytes is dependent on sub-cellular structures called dyads, where invaginations of the surface membrane (t-tubules) form functional junctions with the sarcoplasmic reticulum (SR). Within each dyad, Ca2+ entry through t-tubular L-type Ca2+ channels (LTCCs) elicits Ca2+ release from closely apposed Ryanodine Receptors (RyRs) in ...
Peter P. Jones   +5 more
openaire   +6 more sources

DJ-1 Deficiency Protects against Sepsis-Induced Myocardial Depression

open access: yesAntioxidants, 2023
Oxidative stress is considered one of the early underlying contributors of sepsis-induced myocardial depression. DJ-1, also known as PARK7, has a well-established role as an antioxidant.
James N. Tsoporis   +16 more
doaj   +1 more source

Home - About - Disclaimer - Privacy