Results 11 to 20 of about 160,172 (303)
Pulses and waves of contractility [PDF]
Journal of Cell Biology, 2017 The nature of signal transduction networks in the regulation of cell contractility is not entirely clear. In this study, Graessl et al. (2017. J. Cell Biol. https://doi.org/10.1083/jcb.201706052) visualized and characterized pulses and waves of Rho activation in adherent cells and proposed excitable Rho signaling networks underlying cell contractility.
Min Wu
openaire +3 more sources
Altered excitation-contraction coupling in human chronic atrial fibrillation [PDF]
, 2012 This review focuses on the (mal)adaptive processes in atrial excitation-contraction coupling occurring in patients with chronic atrial fibrillation. Cellular remodeling includes shortening of the atrial action potential duration and effective refractory ...
Grandi, E., Pandit, S.V., Workman, A.J.
core +7 more sources
Noninvasive identification and therapeutic implications of supernormal left ventricular contractile phenotype [PDF]
Exploration of CardiologyLeft ventricular (LV) function is typically evaluated through LV ejection fraction (EF), a robust indicator of risk, showing a nonlinear increase in mortality rates below 40%.
Yi Wang, Lixue Yin
doaj +1 more source
Improved ventricular function during inhalation of PGI(2) aerosol partly relies on enhanced myocardial contractility [PDF]
, 2005 Inhaled prostacyclin (PGI(2)) aerosol induces selective pulmonary vasodilation. Further, it improves right ventricular ( RV) function, which may largely rely on pulmonary vasodilation, but also on enhanced myocardial contractility.
Thein, E. +12 more
core +1 more source
Membranes, 2022 Various models, including stem cells derived and isolated cardiomyocytes with overexpressed channels, are utilized to analyze the functional interplay of diverse ion currents involved in cardiac automaticity and excitation–contraction coupling control ...
Alexey S. Averin +6 more
doaj +1 more source
Analysis of Contractility and Invasion Potential of Two Canine Mammary Tumor Cell Lines
Frontiers in Veterinary Science, 2017 Cancer cells are surrounded by a mechanically and biochemically distinct microenvironment that undergoes dynamic changes throughout the neoplastic progression.
Kaisa Rajakylä +2 more
doaj +1 more source
AI-Based Estimation of End-Systolic Elastance From Arm-Pressure and Systolic Time Intervals
Frontiers in Artificial Intelligence, 2021 Left ventricular end-systolic elastance (Ees) is a major determinant of cardiac systolic function and ventricular-arterial interaction. Previous methods for the Ees estimation require the use of the echocardiographic ejection fraction (EF).
Vasiliki Bikia +4 more
doaj +1 more source
Diabetes is associated with impairment of uterine contractility and high Caesarean section rate [PDF]
, 2011 Aims/hypothesis The prevalence of births worldwide complicated by diabetes mellitus is increasing. In the UK, for example,
S. Al-Qahtani +13 more
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Frontiers in Physiology, 2018 Pirfenidone (PFD) is used to treat human pulmonary fibrosis. Its administration to animals with distinct forms of cardiovascular disease results in striking improvement in cardiac performance.
Adrián Monsalvo-Villegas +2 more
doaj +1 more source
Pathophysiological Mechanisms of Cardiac Dysfunction in Transgenic Mice with Viral Myocarditis
Cells, 2023 Viral myocarditis is pathologically associated with RNA viruses such as coxsackievirus B3 (CVB3), or more recently, with SARS-CoV-2, but despite intensive research, clinically proven treatment is limited.
Matthias Rohrbeck +22 more
doaj +1 more source