Results 11 to 20 of about 217,710 (307)
RhoA GTPase switch controls Cx43-hemichannel activity through the contractile system [PDF]
, 2012 ATP-dependent paracrine signaling, mediated via the release of ATP through plasma membrane-embedded hemichannels of the connexin family, coordinates a synchronized response between neighboring cells.
Bultynck, Geert +7 more
core +9 more sources
Analysis of Contractility and Invasion Potential of Two Canine Mammary Tumor Cell Lines
Frontiers in Veterinary Science, 2017 Cancer cells are surrounded by a mechanically and biochemically distinct microenvironment that undergoes dynamic changes throughout the neoplastic progression.
Kaisa Rajakylä +2 more
doaj +1 more source
AI-Based Estimation of End-Systolic Elastance From Arm-Pressure and Systolic Time Intervals
Frontiers in Artificial Intelligence, 2021 Left ventricular end-systolic elastance (Ees) is a major determinant of cardiac systolic function and ventricular-arterial interaction. Previous methods for the Ees estimation require the use of the echocardiographic ejection fraction (EF).
Vasiliki Bikia +4 more
doaj +1 more source
Current Biology, 2003 What is it? The contractile ring is a ring-shaped structure located just beneath the plasma membrane at the future division site in many, though not all, eukaryotic cell types. Composed of actin, myosin and many other proteins, it assembles in anaphase and contracts as cells divide. The contractile ring is responsible for cytokinesis in many eukaryotic
Chang, Fred, Burgess, David
openaire +2 more sources
The cardiac work-loop technique:An in vitro model for identifying and profiling drug-induced changes in inotropy using rat papillary muscles [PDF]
, 2020 The cardiac work-loop technique closely mimics the intrinsic in vivo movement and characteristics of cardiac muscle function. In this study, six known inotropes were profiled using the work-loop technique to evaluate the potential of this method to ...
AJ Taberner +56 more
core +1 more source
Frontiers in Physiology, 2018 Pirfenidone (PFD) is used to treat human pulmonary fibrosis. Its administration to animals with distinct forms of cardiovascular disease results in striking improvement in cardiac performance.
Adrián Monsalvo-Villegas +2 more
doaj +1 more source
Pathophysiological Mechanisms of Cardiac Dysfunction in Transgenic Mice with Viral Myocarditis
Cells, 2023 Viral myocarditis is pathologically associated with RNA viruses such as coxsackievirus B3 (CVB3), or more recently, with SARS-CoV-2, but despite intensive research, clinically proven treatment is limited.
Matthias Rohrbeck +22 more
doaj +1 more source
Frontiers in Bioengineering and Biotechnology, 2021 Determination of left ventricular (LV) end-systolic elastance (Ees) is of utmost importance for assessing the cardiac systolic function and hemodynamical state in humans. Yet, the clinical use of Ees is not established due to the invasive nature and high
Vasiliki Bikia +6 more
doaj +1 more source
Platelet Contractile Proteins [PDF]
Thrombosis and Haemostasis, 1977 Platelets contain a high concentration of the contractile proteins actin and myosin. The properties of these proteins are generally similar to their counterparts in muscle, suggesting that the platelet actin and myosin can generate contractile force.
openaire +3 more sources
Force Measurements From Myofibril to Filament
Frontiers in Physiology, 2022 Contractility, the generation of force and movement by molecular motors, is the hallmark of all muscles, including striated muscle. Contractility can be studied at every level of organization from a whole animal to single molecules.
Steven Marston
doaj +1 more source