Results 21 to 30 of about 122,620 (268)
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2018 BackgroundAn accurate assessment of intrinsic right ventricular (RV) contractility and its relation to pulmonary arterial load is essential for the management of pulmonary hypertension.
Ryo Inuzuka +3 more
doaj +1 more source
Inflammation and cardiac dysfunction during sepsis, muscular dystrophy, and myocarditis
Burns & Trauma, 2013 Inflammation plays an important role in cardiac dysfunction under different situations. Acute systemic inflammation occurring in patients with severe burns, trauma, and inflammatory diseases causes cardiac dysfunction, which is one of the leading causes ...
Ying Li +3 more
doaj +1 more source
Molecules, 2012 Guanidine has been used with some success to treat myasthenia gravis and myasthenic syndrome because it increases acetylcholine release at nerve terminals through K<sup>+</sup>, Na<sup>+</sup> and Ca<sup>2+</sup> ...
Maria Alice da Cruz Höfling +2 more
doaj +1 more source
Physiological Reports, 2022 Type 2 diabetes (T2D) affects >30 million Americans and nearly 70% of individuals with T2D will die from cardiovascular disease (CVD). Circulating levels of the inflammatory signaling lipid, prostaglandin E2 (PGE2), are elevated in the setting of obesity
Karin J. Bosma +9 more
doaj +1 more source
Platelet Contractile Proteins [PDF]
Thrombosis and Haemostasis, 1977 Platelets contain a high concentration of the contractile proteins actin and myosin. The properties of these proteins are generally similar to their counterparts in muscle, suggesting that the platelet actin and myosin can generate contractile force.
openaire +3 more sources
Frontiers in Pharmacology, 2023 Dysmenorrhea affects women throughout their reproductive years but there has been a lack of effective and well-tolerated treatment options. Pain symptoms mainly result from inflammatory processes and increased contractile activity in the myometrium.
Leonie Zurfluh +5 more
doaj +1 more source
Contraction of Stress Fibers Extracted from Smooth Muscle Cells: Effects of Varying Ionic Strength
Journal of Biomechanical Science and Engineering, 2012 Actin stress fibers (SFs) play a key role in regulation of cell adhesion, but the biochemical and biophysical properties intrinsic to SFs remain unclear. Here we extracted SFs from rat embryonic smooth muscle cells by deroofing, and evaluated the effects
Shinji DEGUCHI +3 more
doaj +1 more source
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Chronic high‐dose testosterone treatment: impact on rat cardiac contractile biology
Physiological Reports, 2019 Androgen therapy provides cardiovascular benefits for hypogonadism. However, myocardial hypertrophy, fibrosis, and infarction have been reported in testosterone or androgenic anabolic steroid abuse.
Munthana Wadthaisong +4 more
doaj +1 more source
Symmetry Breaking and Epithelial Cell Extrusion
Cells, 2020 Cell extrusion is a striking morphological event found in epithelia and endothelia. It is distinguished by two symmetry-breaking events: a loss of planar symmetry, as cells are extruded in either apical or basal directions; and loss of mechanochemical ...
Bageshri Naimish Nanavati +2 more
doaj +1 more source