Results 61 to 70 of about 1,740,794 (265)

Nomograms for predicting overall survival and cancer-specific survival in patients with surgically resected intrahepatic cholangiocarcinoma

Cancer Management and Research, 2019
Kexin Ma,* Bing Dong,* Liming Wang, Chongyu Zhao, Zhaoyu Fu, Chi Che, Wuguang Liu, Zexuan Yang, Rui LiangDepartment of Hepatobiliary Surgery, The Second Hospital of Dalian Medical University, Dalian, Liaoning, People’s Republic of China*These ...
Ma K, Dong B, Wang L, Zhao C, Fu Z, Che C, Liu W, Yang Z, Liang R   +8 more
doaj  

Evaluating overall survival and competing risks of survival in patients with early‐stage breast cancer using a comprehensive nomogram

Cancer Medicine, 2020
Background Patients with early‐stage breast cancer (BC) live long but have competing comorbidities. This study aimed to estimate the effect of cancer and other causes of death in patients with early‐stage BC and further quantify the survival differences.
Yan‐Bo Xu, Hong Liu, Qi‐Hua Cao, Jia‐Li Ji, Rong‐Rong Dong, Dong Xu   +5 more
doaj   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Interpreting overall survival results when progression-free survival benefits exist in today's oncology landscape: a metastatic renal cell carcinoma case study

Cancer Management and Research, 2014
Yiyun Tang,1 Paul Bycott,1 Örjan Åkerborg,2 Linus Jönsson,2 Sylvie Negrier,3 Connie Chen4 1Pfizer Global Research and Development, La Jolla, CA, USA; 2OptumInsight, Stockholm, Sweden; 3Medical Oncology Department, University of Lyon, Lyon,
Tang Y, Bycott P, Åkerborg Ö, Jönsson L, Negrier S, Chen C   +5 more
doaj  

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Nomograms to predict overall survival and cancer-specific survival in patients with adrenocortical carcinoma

Cancer Management and Research, 2018
Yan Li,1 Xiaohui Bian,2 Junyu Ouyang,2 Shuyi Wei,2 Meizhi He,2 Zelong Luo1 1Department of Oncology, Zhujiang Hospital of Southern Medical University, Guangzhou, Guangdong, China; 2The Second School of Clinical Medicine, Southern Medical University ...
Li Y, Bian XH, Ouyang JY, Wei SY, He MZ, Luo ZL   +5 more
doaj  

Prognostic and predictive value of radiomics signatures in stage I‐III colon cancer

Clinical and Translational Medicine, 2020
Accurate identification of patients with poor prognosis after radical surgery is essential for clinical management of colon cancer. Thus, we aimed to develop death and relapse specific radiomics signatures to individually estimate overall survival (OS ...
Weixing Dai, Shaobo Mo, Lingyu Han, Wenqiang Xiang, Menglei Li, Renjie Wang, Tong Tong, Guoxiang Cai   +7 more
doaj   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

FEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens, Brendan W. Chandler, Anna M. Schmoker, Jaye L. Weinert, Charlotte A. Kearns, Warren T. Yacawych, Amila Šemić, Alicia M. Ebert, Bryan A. Ballif   +8 more
wiley   +1 more source

A Longitudinal Study of AFP Trajectories and Clinical Outcomes in Intermediate-Stage Hepatocellular Carcinoma After Hepatectomy

Journal of Hepatocellular Carcinoma
Hongyi Yang,1,* Linbin Lu,1,* Wanting Guo,2 Baocuo Gong,2 Xuewen Wang,1 Yaying Chen,1 Xiong Chen1 1Department of Oncology, Mengchao Hepatobiliary Hospital of Fujian Medical University, Fuzhou, People’s Republic of China; 2Department of Oncology ...
Yang H, Lu L, Guo W, Gong B, Wang X, Chen Y, Chen X   +6 more
doaj  

The extremity localized classic osteosarcomas have better survival than the axial non-classics

World Journal of Surgical Oncology, 2018
Background Osteosarcoma is one of the most malignant primary bone cancers, while is rarely reported in China. Of note, very few data of prognosis has been documented in this region.
Li Lin, Shaoyong Deng, Futing Zhang, Yaoze Liang, Zhenhua Huang   +4 more
doaj   +1 more source