Results 81 to 90 of about 1,740,794 (265)

The role of temozolomide as adjuvant therapy in glioblastoma management: a systematic review and meta-analysis.

open access: yesBMC Cancer
Introduction The persistent challenge of temozolomide (TMZ) resistance and the eventual recurrence of tumors underscore the need for ongoing research and the development of novel therapeutic strategies.
Made Agus Mahendra Inggas   +13 more
doaj   +1 more source

Long Non-Coding RNAs ASB16-AS1 and AFAP1-AS1: Diagnostic, Prognostic Impact and Survival Analysis in Colorectal Cancer

open access: yesThe Application of Clinical Genetics, 2022
Naglaa S Elabd,1 Shimaa E Soliman,2 Moamena S Elhamouly,1 Suzy F Gohar,3 Ayman Elgamal,4 Mahmoud Magdy Alabassy,5 Haitham A Soliman,5 Abdelnaser A Gadallah,6 Osama D Elbahr,7 Ghada Soliman,3 Amany A Saleh2 1Tropical Medicine Department, Faculty of ...
Elabd NS   +10 more
doaj  

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

open access: yesFEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança   +2 more
wiley   +1 more source

Low Serum Cholinesterase Levels Predict Poor Prognosis in Patients with Ovarian Cancer

open access: yesInternational Journal of General Medicine
Hailan Su,1,* Danfeng Liao,2,* Chaolin Huang,2 Qin Liu,3 Lingfang Yu1 1Department of Gynecology, Suzhou Ninth People’s Hospital, Suzhou, People’s Republic of China; 2Department of Gynecology and Obstetrics, The First Affiliated Hospital of ...
Su H, Liao D, Huang C, Liu Q, Yu L
doaj  

Prognostic analysis of sleeve lobectomy for non-small cell lung cancer

open access: yesZhongguo aizheng zazhi, 2018
Background and purpose: Sleeve lobectomy is considered an acceptable surgery for patients with central lung cancer, and can preserve more lung functions because of the reservation of the normal lung tissues.
郑佳杰, 罗继壮
doaj  

Surrogacy of one-year survival for overall survival in advanced hepatocellular carcinoma

open access: yesBMC Cancer
Background The increasing number of sequential treatments complicates the evaluation of overall survival (OS) in clinical trials for hepatocellular carcinoma (HCC), therefore, reliable surrogate endpoints (SEs) are required.
Yuzhi Jin   +6 more
doaj   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

open access: yesFEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Unveiling the Landscape of PD-L1 Expression and Tumor-Infiltrating Lymphocyte Subtypes in Advanced Triple-Negative Breast Cancer in Brazil

open access: yesBreast Cancer: Targets and Therapy
Alexssandra Lima Siqueira Dos Santos,1 Jesse Lopes Da Silva,1 Lucas Zanetti De Albuquerque,1 Antônio Lucas Araújo Neto,1 Cecília Ferreira Da Silva,1 Luana Aguiar Mesquita Cerva,1 Isabele Avila Small,1 Fabiana Resende Rodrigues,2 Fabiane Carvalho De ...
Dos Santos ALS   +13 more
doaj  

Metastatic niche shaped by host factors influences disseminated cancer cell fate

open access: yesFEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward   +2 more
wiley   +1 more source

Negative Impact of Intra-Operative Blood Transfusion on Survival Outcomes of Hepatocellular Carcinoma Patients

open access: yesCancer Management and Research
Lei Teng, Liuyuan Zhao, Hongxue Shao, Junzhu Dai, Huichao Zou Department of Pain Medicine, Harbin Medical University Cancer Hospital, Harbin, People’s Republic of ChinaCorrespondence: Huichao Zou, Department of Pain Medicine, Harbin Medical University ...
Teng L, Zhao L, Shao H, Dai J, Zou H
doaj  

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