Molecular Oncology, EarlyView.Using multi‐omic characterization, we aimed to identify key regulators specific to squamous cell lung carcinoma (SqCC). SqCC‐specific differentially expressed genes were integrated with metabolics data. High expression of the creatine transporter SLC6A8, along with elevated creatine levels, appeared to be a distinct metabolic feature of SqCC.
Johan Staaf +10 more
wiley +1 more source
Nomogram Based on A-To-I RNA Editing for Predicting Overall Survival in Patients With Breast Cancer. [PDF]
J Cell Mol MedZhang Y +7 more
europepmc +1 more source
TP53 codon 72 polymorphism in susceptibility, overall survival, and adjuvant therapy response of gliomas [PDF]
, 2007 Vítor Lima-Ramos +7 more
openalex +1 more source
Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine
Molecular Oncology, EarlyView.The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu +18 more
wiley +1 more source
MRI-based risk stratification for predicting overall survival in pancreatic ductal adenocarcinoma. [PDF]
Insights ImagingSun H +13 more
europepmc +1 more source
Relevance of CD49d protein expression as overall survival and progressive disease prognosticator in chronic lymphocytic leukemia [PDF]
, 2007 Valter Gattei +12 more
openalex +1 more source
Molecular Oncology, EarlyView.This study highlights the potential of automated enumeration using the ACCEPT software to refine circulating tumor cell (CTC) detection in metastatic colorectal cancer (mCRC). The automated method demonstrates improved accuracy and reduced variability compared to the manual approach.
Michela De Meo +6 more
wiley +1 more source
Predictive value of Geriatric Nutritional Risk Index for overall survival in maintenance hemodialysis patients. [PDF]
Front NutrHe H, Yang Y.
europepmc +1 more source
Cardiac Surgery in Patients on Dialysis: Decreased 30-Day Mortality, Unchanged Overall Survival [PDF]
, 2007 Matthias Bechtel +10 more
openalex +1 more source
A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression
Molecular Oncology, EarlyView.Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak +8 more
wiley +1 more source