Results 31 to 40 of about 1,877,507 (306)

Progression-free survival versus post-progression survival and overall survival in WHO grade 2 gliomas

Acta Oncologica
Background and purpose: Progression-free survival (PFS) remains to be validated as an outcome measure for diffuse WHO grade 2 gliomas, and knowledge about the relationships between PFS, post-progression survival (PPS), and overall survival (OS) in this ...
Lisa Millgård Sagberg, Øyvind Salvesen, Asgeir Store Jakola, Erik Thurin, Eddie de Dios, Noah L.A. Nawabi, John L. Kilgallon, Joshua D. Bernstock, Vasileios K. Kavouridis, Timothy R. Smith, Ole Solheim   +10 more
doaj   +1 more source

Improved estimation of overall survival and progression-free survival for state transition modeling

Journal of Comparative Effectiveness Research, 2023
Aim: National Institute for Health and Care Excellence guidance (Technical Support Document 19) highlights a key challenge of state transition models (STMs) being their difficulty in achieving a satisfactory fit to the observed within-trial endpoints ...
Peter C Wigfield, Bart Heeg, Mario Ouwens   +2 more
doaj   +1 more source

The impact of previous cancer on overall survival of bladder cancer patients and the establishment of nomogram for overall survival prediction

Medicine, 2020
To investigate the role of previous cancer on overall survival in patients with bladder cancer (BCa) and to establish an effective prognostic tool for individualized overall survival prediction.A total of 78,660 patients diagnosed with BCa between 2000 and 2013 were selected from the Surveillance, Epidemiology, and End Results (SEER) database, among ...
Wang, Zhengquan, Zhou, Yuan, Guan, Chao, Ding, Yinman, Tao, Sha, Huang, Xiaoqi, Chen, Liang, Zhang, Fei, Zhang, Rentao   +8 more
openaire   +2 more sources

A novel nomogram to predict the overall survival in esthesinoeroblastoma [PDF]

BMC Cancer, 2020
Abstract Background Increasing evidence indicates that the pathology and the modified Kadish system have some influence on the prognosis of esthesioneuroblastoma (ENB). However, an accurate system to combine pathology with a modified Kadish system has not been established.
Lijie Jiang, Tengjiao Lin, Yu Zhang, Wenxiang Gao, Jie Deng, Zhaofeng Xu, Xin Luo, Zhaoqi Huang, Fenghong Chen, Jianbo Shi, Yinyan Lai   +10 more
openaire   +3 more sources

Clinical and Biological Features of Response in Resistant Neuroblastoma to 131I‐Metaiodobenzylguanidine Radiotherapy in the Anti‐GD2 Immunotherapy Era

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background 131I‐metaiodobenzylguanidine (131I‐MIBG) radiotherapy is a key treatment for relapsed and refractory (R/R) neuroblastoma (NB). Patients with R/R disease treated in the modern era are increasingly exposed to anti‐GD2 immunotherapy, which exerts selective pressure and may modify both tumor cell state and microenvironment.
Benjamin J. Lerman, Katherine K. Matthay, Fabienne Hollinger, Catriona Black, Ann A. Lazar, Miguel Pampaloni, Steven G. DuBois, Kieuhoa T. Vo   +7 more
wiley   +1 more source

Epidemiology, diagnostics and long-term overall survival of patients with non-small cell lung cancer in the Brest Region

Studia Medyczne, 2013
Introduction: Lung cancer has been the most common cancer in the world and in Belarus. Aim of the research: To evaluate the epidemiology of non-small cell lung cancer and improvements in diagnostics and treatment for the past 11 years in the Brest ...
Siarhei Panko, Aleksandr Karpitski, Konstantin Shelepen, Mikalaj Kazarez, Denis Vakulich, Rostislaw Boufalik, Andrej Shestiuk, Genadz Zhurbenka, Alaksandr Ignatiuk   +8 more
doaj   +1 more source

Deep Sequencing of FLT3‐ITD Enables Response Evaluation and Post‐Treatment Monitoring in Childhood AML: An Exploratory Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background An internal tandem duplication in the gene encoding Fms‐like tyrosine kinase 3 (FLT3‐ITD) is associated with high relapse risk and poor prognosis in acute myeloid leukemia (AML) and plays a crucial role in treatment decisions. Measurable residual disease (MRD) analysis of FLT3‐ITD during and after treatment has shown prognostic ...
Sofie Johansson Alm, Bea Tornberg, Erik Delsing Malmberg, Henrik Hasle, Kristian Løvvik Juul‐Dam, Lars Palmqvist, Borhan R. Saeed, Giti Shah Barkhordar, Anastasia Soboli, Anna Staffas, Jonas Abrahamsson, Linda Fogelstrand   +11 more
wiley   +1 more source

Overall survival.

, 2016
Kaplan Meier estimates of overall survival evaluated from the date of lapatinib-based therapy initiation in 132 patients according to PFS >7 months (solid line) or PFS ≤7 months (dashed line). Median overall survival is 36 months (95% C.I.
Arianna Pellegrino (2805724), Giancarlo Bisagni (792338), Ida Pavese (2805727), Stefania Gori (591005), Daniele Santini (222870), Simona Duranti (792335), Elena Fiorio (792327), Patrizia Vici (85361), Alessandro Inno (792326), Valentina Rossi (79904), Gianluigi Lunardi (792352), Alberto Zambelli (10715), Giuseppe Bogina (792351), Monica Turazza (792334), Sandro Barni (477365), Filippo Montemurro (2805733), Jennifer Foglietta (792328), Vita Leonardi (2805730), Silvana Saracchini (792345), Alessandra Fabi (85359), Fabiana Marchetti (792350)   +20 more
core   +3 more sources

Prediction of Overall Survival of Brain Tumor Patients [PDF]

TENCON 2019 - 2019 IEEE Region 10 Conference (TENCON), 2019
Automated brain tumor segmentation plays an important role in the diagnosis and prognosis of the patient. In addition, features from the tumorous brain help in predicting patients overall survival. The main focus of this paper is to segment tumor from BRATS 2018 benchmark dataset and use age, shape and volumetric features to predict overall survival of
Rupal R. Agravat, Mehul S. Raval
openaire   +2 more sources

Claudin‐6 Protein Expression in Atypical Teratoid/Rhabdoid Tumors Is Strongly Enriched in the Molecular Subgroup AT/RT‐TYR

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Claudin‐6 has emerged as a promising immunotherapeutic target, yet protein‐level data in atypical teratoid/rhabdoid tumors (AT/RTs) have been inconsistent. We analyzed 36 well‐characterized AT/RT samples and found membranous claudin‐6 protein expression in 58% of cases, with striking enrichment in the molecular subgroup AT/RT‐TYR (100%) and ...
Victoria E. Fincke, Christian Thomas, Michael C. Frühwald, Pascal D. Johann, Martin Hasselblatt   +4 more
wiley   +1 more source