Results 191 to 200 of about 320,909 (424)

Large Language Models for Drug Overdose Prediction from Longitudinal Medical Records [PDF]

open access: yesarXiv
The ability to predict drug overdose risk from a patient's medical records is crucial for timely intervention and prevention. Traditional machine learning models have shown promise in analyzing longitudinal medical records for this task. However, recent advancements in large language models (LLMs) offer an opportunity to enhance prediction performance ...
arxiv  

Linking individual variation in facial musculature to facial behavior in rhesus macaques

open access: yesThe Anatomical Record, EarlyView.
Abstract Facial expression is a key component of primate communication, and primates (including humans) have a complex system of facial musculature underpinning this behavior. Human facial musculature is highly variable across individuals, but to date, whether other primate species exhibit a similar level of inter‐individual variation is unknown ...
Clare M. Kimock   +7 more
wiley   +1 more source

Contemporary management of pain in cirrhosis: Toward precision therapy for pain

open access: yesHepatology, EarlyView., 2022
Abstract Chronic pain is highly prevalent in patients with cirrhosis and is associated with poor health‐related quality of life and poor functional status. However, there is limited guidance on appropriate pain management in this population, and pharmacologic treatment can be harmful, leading to adverse outcomes, such as gastrointestinal bleeding ...
Alexis Holman   +4 more
wiley   +1 more source

A comparison of heroin epidemic models [PDF]

open access: yesarXiv, 2015
The use of illicit drugs has been on the rise in United States. It is very detrimental on society, as fatal overdose is the fourth leading cause of death in the United States, which is about the same as motor vehicle crashes. Of all illicit drugs, one drug that has an severe adverse effect on a community as a whole is heroin.
arxiv  

Intestinal responses in pacu (Piaractus mesopotamicus) exposed to fasting and refeeding nutritional management

open access: yesThe Anatomical Record, EarlyView.
Abstract Fasting is a practice in the aquaculture industry that aims to reduce feed costs. This practice can affect the gastrointestinal system of fish. The intestine plays a pivotal role in the nutrition and overall health of fishes. The present study sought to evaluate the effects of fasting and refeeding on body weight, intestine somatic index (ISI),
Karine Nathiele Nogueira Farias   +7 more
wiley   +1 more source

CHARCOAL HAEMOPERFUSION FOR PARACETAMOL OVERDOSE [PDF]

open access: bronze, 1974
B G Gazzard   +4 more
openalex   +1 more source

Noradrenergic and cholinergic innervation of the normal human heart and changes associated with cardiomyopathy

open access: yesThe Anatomical Record, EarlyView.
Abstract Autonomic nerves are crucial in cardiac function and pathology. However, data on the distribution of cholinergic and noradrenergic nerves in normal and pathologic human hearts is lacking. Nonfailing donor hearts were pressure‐perfusion fixed, imaged, and dissected. Left ventricular cardiomyopathy samples were also obtained.
Peter Hanna   +15 more
wiley   +1 more source

Combinatorial targeting of G‐protein‐coupled bile acid receptor 1 and cysteinyl leukotriene receptor 1 reveals a mechanistic role for bile acids and leukotrienes in drug‐induced liver injury

open access: yesHepatology, EarlyView., 2022
CHIN117 is a dual cysteinyl leukotriene receptor 1 (CYSLTR1) antagonist and G‐protein‐coupled bile acid receptor 1 (GPBAR1) agonist. In the liver, GPBAR1 and CYSLTR1 are coexpressed by liver sinusoidal endothelial cells (LSECs), HSCs, circulating monocytes/macrophages, and liver resident macrophages (Kupffer cells).
Michele Biagioli   +13 more
wiley   +1 more source

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