Results 51 to 60 of about 320,909 (424)

Xylazine Spreads Across the US: A Growing Component of the Increasingly Synthetic and Polysubstance Overdose Crisis

medRxiv, 2021
Background: Recent sharp exacerbations of the US overdose crisis have been linked to systemic polysubstance use and potent synthetic compounds in numerous drug classes. Xylazine is a veterinary tranquilizer, long noted in the opioid supply of Puerto Rico,
Joseph R. Friedman, Fernando Montero, Phillippe Bourgois, Rafik Wahbi, Daniel Dye, David Goodman-Meza, Chelsea L. Shover   +6 more
semanticscholar   +1 more source

Exploring the Journey to Drug Overdose: Applying the Journey to Crime Framework to Drug Sales Locations and Overdose Death Locations [PDF]

arXiv, 2023
Drug overdose is a pressing public health concern in the United States, resulting in a significant number of fatalities each year. In this study, we employ the Journey to Crime (JTC) framework borrowed from the field of environmental criminology to examine the association between drug sales locations and overdose death locations.
arxiv  

Increased risk of HIV and other drug-related harms associated with injecting in public places: national bio-behavioural survey of people who inject drugs [PDF]

, 2020
Background: Whilst injecting drugs in public places is considered a proxy for high risk behaviour among people who inject drugs (PWID), studies quantifying its relationship with multiple drug-related harms are lacking and none have examined this in the ...
Goldberg, David J., Gunson, Rory N, Hutchinson, Sharon J., McAuley, Andrew, Milosevic, Catriona, Palmateer, Norah E., Priyadarshi, Saket, Shepherd, Samantha J., Trayner, Kirsten M.A., Tweed, Emily J   +9 more
core   +2 more sources

“Ghost tablet” husks excreted in feces in large bupropion XL overdose [PDF]

, 2018
Background: Extended-release medications are widely prescribed across the spectrum of medical specialties; however, there is heterogeneity in how they are formulated.
Nanagas, Kristine, Overberg, Adam, Purpura, Andrea   +2 more
core   +1 more source

Personal experience and awareness of opioid overdose occurrence among peers and willingness to administer naloxone in South Africa: findings from a three-city pilot survey of homeless people who use drugs

Harm Reduction Journal, 2022
Background Drug overdoses occur when the amount of drug or combination of drugs consumed is toxic and negatively affects physiological functioning. Opioid overdoses are responsible for the majority of overdose deaths worldwide.
Michael Wilson, Amanda Brumwell, M. J. Stowe, Shaun Shelly, Andrew Scheibe   +4 more
doaj   +1 more source

Association between county-level sociodemographic characteristics and county-level differences in opioid dispensing

Preventive Medicine Reports, 2021
Background: While overall opioid prescribing has been decreasing in the United States, the rates of prescribing at the county level have been variable. Previous studies show that social determinants of health (the social and economic conditions in which ...
Laura J. Cremer, Natasha Underwood, Amber Robinson, Gery P. Guy, Jr, Cherie R. Rooks-Peck   +4 more
doaj  

Association of Dose Tapering With Overdose or Mental Health Crisis Among Patients Prescribed Long-term Opioids.

Journal of the American Medical Association (JAMA), 2021
Importance Opioid-related mortality and national prescribing guidelines have led to tapering of doses among patients prescribed long-term opioid therapy for chronic pain.
A. Agnoli, G. Xing, D. Tancredi, Elizabeth M Magnan, A. Jerant, J. Fenton   +5 more
semanticscholar   +1 more source

Increases in Drug and Opioid Overdose Deaths--United States, 2000-2014.

MMWR. Morbidity and mortality weekly report, 2016
The United States is experiencing an epidemic of drug overdose (poisoning) deaths. Since 2000, the rate of deaths from drug overdoses has increased 137%, including a 200% increase in the rate of overdose deaths involving opioids (opioid pain relievers ...
R. A. Rudd, Noah Aleshire, Jon E. Zibbell, R. M. Gladden   +3 more
semanticscholar   +2 more sources

Racial and Ethnic Disparities in Drug Overdose Deaths in the US During the COVID-19 Pandemic

JAMA Network Open, 2022
This cross-sectional study describes the nationwide trends in drug overdose mortality during the COVID-19 pandemic by age, sex, and race and ethnicity.
B. Han, Emily B. Einstein, Christopher M. Jones, Jessica H Cotto, W. Compton, N. Volkow   +5 more
semanticscholar   +1 more source

Routes of Drug Use Among Drug Overdose Deaths — United States, 2020–2022

MMWR. Morbidity and mortality weekly report
Preliminary reports indicate that more than 109,000 drug overdose deaths occurred in the United States in 2022; nearly 70% of these involved synthetic opioids other than methadone, primarily illegally manufactured fentanyl and fentanyl analogs (IMFs ...
ScD Lauren J. Tanz, PhD R. Matt Gladden, Mph Amanda T. Dinwiddie, Mph Kimberly D. Miller, PhD Dita Broz, MS Eliot Spector, PhD Julie O’Donnell   +6 more
semanticscholar   +1 more source