Results 31 to 40 of about 1,616,124 (301)

Bridging the Gap: Implementation and Uptake of AUDIT-C Alcohol Screening for Inpatient Surgery

Annals of Surgery Open
Objective:. To evaluate the feasibility of Alcohol Use Disorders Identification Test-Consumption (AUDIT-C) screening among surgical inpatients following hospital-wide implementation of a quality improvement initiative. Background:.
Toby Chen, BS, Dominic Alessio, BS, Anne Fernandez, PhD, Sarah Evilsizer, BSN, Chiao-Li Chan, MSW, Vidhya Gunaseelan, MBA, MS, MHA, Jennifer F. Waljee, MD, MPH, MS, Mark C. Bicket, MD, PhD   +7 more
doaj   +1 more source

Combinatorial targeting of G‐protein‐coupled bile acid receptor 1 and cysteinyl leukotriene receptor 1 reveals a mechanistic role for bile acids and leukotrienes in drug‐induced liver injury

Hepatology, EarlyView., 2022
CHIN117 is a dual cysteinyl leukotriene receptor 1 (CYSLTR1) antagonist and G‐protein‐coupled bile acid receptor 1 (GPBAR1) agonist. In the liver, GPBAR1 and CYSLTR1 are coexpressed by liver sinusoidal endothelial cells (LSECs), HSCs, circulating monocytes/macrophages, and liver resident macrophages (Kupffer cells).
Michele Biagioli, Silvia Marchianò, Cristina di Giorgio, Rosalinda Roselli, Martina Bordoni, Rachele Bellini, Bianca Fiorillo, Valentina Sepe, Bruno Catalanotti, Chiara Cassiano, Maria Chiara Monti, Eleonora Distrutti, Angela Zampella, Stefano Fiorucci   +13 more
wiley   +1 more source

Fighting Fatality: Insight into British Columbia’s Sanctioning of Overdose Prevention Sites

Health Reform Observer - Observatoire des Réformes de Santé, 2020
Due to the alarming rate of illicit drug toxicity deaths in British Columbia, a public health emergency was declared by Provincial Health Officer Dr. Perry Kendall on 14 April 2016.
Nicole Marie Davidson
doaj   +1 more source

Peer Support and Overdose Prevention Responses: A Systematic 'State-of-the-Art' Review [PDF]

, 2021
Overdose prevention for people who use illicit drugs is essential during the current overdose crisis. Peer support is a process whereby individuals with lived or living experience of a particular phenomenon provide support to others by explicitly drawing
Tessa Parkes, Miler, Joanna Astrid, Hannah Carver, Kristina Hnízdilová, Foster, Rebecca, Bernie Pauly, Mercer, Fiona, Joanna Astrid Miler, Parkes, Tessa, Hnízdilová, Kristina, Carver, Hannah, Fiona Mercer, Hn�zdilov�, Kristina, Rebecca Foster, Pauly, Bernie   +14 more
core   +1 more source

Physicians’ Self-Reported Knowledge and Behaviors Related to Prescribing Opioids for Chronic Pain and Diagnosing Opioid Use Disorder, DocStyles, 2020

AJPM Focus
Introduction: In 2016, the Centers for Disease Control and Prevention released the Guideline for Prescribing Opioids for Chronic Pain (2016 Centers for Disease Control and Prevention Guideline) to improve opioid prescribing while minimizing associated ...
Kathleen R. Ragan-Burnett, MSPH, C. Robinette Curtis, MD, Kristine M. Schmit, MD, Christina A. Mikosz, MD, Lyna Z. Schieber, MD, Gery P. Guy, Jr, PhD, Tamara M. Haegerich, PhD   +6 more
doaj   +1 more source

A Holistic Platform Approach for Developing Robust Pulmonary mRNA Delivery: Integrating Novel Phenolic Acid‐Derived Ionizable Lipids and Device Engineering

Advanced Functional Materials, EarlyView.
An integrated pulmonary mRNA delivery platform combining novel biodegradable syringic acid‐derived ionizable lipids, design‐of‐experiments formulation optimization, and vibrating‐mesh nebulizer engineering enabled stable aerosolization and efficient lung delivery.
Neha Kaushal, Younan Ma, Asad Khanmohammed, Dipen Parande, Hanming Zhang, Saket Dolare, Juliet Chen, Apiwat Wangweerawong, Saswata Karmakar, Hongfeng Deng, Frank Koppenhagen, Shraddha Sharma, Eric Reyes, Sherry He, Lianne Boeglin, Caroline Woo, Azadeh Paksa, Ayed Allawzi, Anusha Dias, Gregory Troiano, Shrirang Karve, Frank DeRosa   +21 more
wiley   +1 more source

Association between inpatient AUDIT-C alcohol screening scores and postoperative outcomes: a retrospective cohort study

BMJ Open
Objectives To evaluate whether alcohol use severity, as measured by the Alcohol Use Disorders Identification Test-Consumption (AUDIT-C), is associated with postoperative complications, hospital utilisation and opioid prescribing among adult surgical ...
Mark C Bicket, Jennifer F Waljee, Vidhya Gunaseelan, Chiao-Li Chan, Anne C Fernandez, Toby Chen, Sarah Evilsizer   +6 more
doaj   +1 more source

Opioid Education and Nasal Naloxone Rescue Kits in the Emergency Department

Western Journal of Emergency Medicine, 2015
Introduction: Emergency departments (EDs) may be high-yield venues to address opioid deaths with education on both overdose prevention and appropriate actions in a witnessed overdose.
Dwyer, Kristin , Walley, Alexander Y. , Langlois, Breanne K. , Mitchell, Patricia M. , Nelson, Kerrie P. , Cromwell, John, Bernstein, Edward   +6 more
doaj   +1 more source

Strategies for preventing heroin overdose

BMJ, 2003
Making naloxone available in addicts9 homes is one of several official or unofficial ways that are being tried out to reduce the rising toll of fatalities from heroin overdose.
openaire   +4 more sources

Pressure‐Assisted Drug Delivery Using High‐Pressure Balloon Platform Improves Vascular Drug Penetration and Anti‐Restenotic Effects

Advanced Healthcare Materials, EarlyView.
A dual‐layer high‐pressure drug‐coated balloon (HP@DCB) increased balloon‐wall contact and promoted deeper paclitaxel (PTX) penetration than a conventional noncompliant DCB. In in vivo study, HP@DCB treatment improved luminal patency and reduced neointimal hyperplasia, supporting pressure‐assisted drug delivery as a promising strategy for enhancing the
Seung Jin Eo, So Yun Lim, Dong‐Sung Won, Ji Won Kim, Yubeen Park, Song Hee Kim, Hyemin Lee, Jung‐Min Ahn, Jun‐Kyu Park, Do‐Yoon Kang, Jung‐Hoon Park   +10 more
wiley   +1 more source