Results 31 to 40 of about 1,514,926 (296)

Fighting Fatality: Insight into British Columbia’s Sanctioning of Overdose Prevention Sites

Health Reform Observer - Observatoire des Réformes de Santé, 2020
Due to the alarming rate of illicit drug toxicity deaths in British Columbia, a public health emergency was declared by Provincial Health Officer Dr. Perry Kendall on 14 April 2016.
Nicole Marie Davidson
doaj   +1 more source

Physicians’ Self-Reported Knowledge and Behaviors Related to Prescribing Opioids for Chronic Pain and Diagnosing Opioid Use Disorder, DocStyles, 2020

AJPM Focus
Introduction: In 2016, the Centers for Disease Control and Prevention released the Guideline for Prescribing Opioids for Chronic Pain (2016 Centers for Disease Control and Prevention Guideline) to improve opioid prescribing while minimizing associated ...
Kathleen R. Ragan-Burnett, MSPH, C. Robinette Curtis, MD, Kristine M. Schmit, MD, Christina A. Mikosz, MD, Lyna Z. Schieber, MD, Gery P. Guy, Jr, PhD, Tamara M. Haegerich, PhD   +6 more
doaj   +1 more source

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

FEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin, Naghme Radmannia, David N. Huynh, Liliane Ménard, Caroline Daneault, Maïté Veilleux, Ahsanullah Ahsanullah, André C. Carpentier, William D. Lubell, Matthieu Ruiz, Huy Ong, Sylvie Marleau, Simon‐Pierre Gravel   +12 more
wiley   +1 more source

Association between inpatient AUDIT-C alcohol screening scores and postoperative outcomes: a retrospective cohort study

BMJ Open
Objectives To evaluate whether alcohol use severity, as measured by the Alcohol Use Disorders Identification Test-Consumption (AUDIT-C), is associated with postoperative complications, hospital utilisation and opioid prescribing among adult surgical ...
Mark C Bicket, Jennifer F Waljee, Vidhya Gunaseelan, Chiao-Li Chan, Anne C Fernandez, Toby Chen, Sarah Evilsizer   +6 more
doaj   +1 more source

Opioid Education and Nasal Naloxone Rescue Kits in the Emergency Department

Western Journal of Emergency Medicine, 2015
Introduction: Emergency departments (EDs) may be high-yield venues to address opioid deaths with education on both overdose prevention and appropriate actions in a witnessed overdose.
Dwyer, Kristin , Walley, Alexander Y. , Langlois, Breanne K. , Mitchell, Patricia M. , Nelson, Kerrie P. , Cromwell, John, Bernstein, Edward   +6 more
doaj   +1 more source

A Holistic Platform Approach for Developing Robust Pulmonary mRNA Delivery: Integrating Novel Phenolic Acid‐Derived Ionizable Lipids and Device Engineering

Advanced Functional Materials, EarlyView.
An integrated pulmonary mRNA delivery platform combining novel biodegradable syringic acid‐derived ionizable lipids, design‐of‐experiments formulation optimization, and vibrating‐mesh nebulizer engineering enabled stable aerosolization and efficient lung delivery.
Neha Kaushal, Younan Ma, Asad Khanmohammed, Dipen Parande, Hanming Zhang, Saket Dolare, Juliet Chen, Apiwat Wangweerawong, Saswata Karmakar, Hongfeng Deng, Frank Koppenhagen, Shraddha Sharma, Eric Reyes, Sherry He, Lianne Boeglin, Caroline Woo, Azadeh Paksa, Ayed Allawzi, Anusha Dias, Gregory Troiano, Shrirang Karve, Frank DeRosa   +21 more
wiley   +1 more source

Facilitating access to supervised smoking facilities: a qualitative study

Harm Reduction Journal
Introduction The implementation of supervised smoking facilities (SSFs) as a harm reduction intervention has public health benefits for people who inhale drugs, but there are significant knowledge gaps surrounding the perspectives of SSF visitors and ...
Courteney Wettemann, Jeffrey Morgan, Tara Taylor, Ardina Boll, Scott Maxwell, Lindsey Richardson, Seonaid Nolan, Jenna van Draanen   +7 more
doaj   +1 more source

41538 Characterizing Opioid Overdose Hotspots for Targeted Overdose Prevention and Treatment

Journal of Clinical and Translational Science, 2021
IMPACT: Identifying factors associated with opioid overdoses will enable better resource allocation in communities most impacted by the overdose epidemic.
Elizabeth A. Samuels, William Goedel, Lauren Conkey, Jennifer Koziol, Sarah Karim, Rachel P. Scagos, Lee Ann Jordison Keeler, Rachel Yorlets, Neha Reddy, Sara Becker, Roland Merchant, Brandon D. L. Marshall   +11 more
doaj   +1 more source

Overdose Detection Technologies to Reduce Solitary Overdose Deaths: A Literature Review

, 2023
Drug overdoses were a leading cause of injury and death in the United States in 2021. Solitary drug use and solitary overdose deaths have remained persistent challenges warranting additional attention throughout the overdose epidemic.
Alexa Rose Lombardi, Ju Nyeong Park, Ralph Welwean, Joseph G. Rosen, Josiah D. Rich, Jessica Tardif, Ritikraj Arya, Erin Thompson   +7 more
core   +1 more source

Tumor‐Targeted Hyaluronic Acid/Tannic Acid‐Engineered Oxygen Nanogenerators With IR780 Payloads Enable Dual‐Mode Glutathione Depletion and Effective Singlet Oxygen Generation for Melanoma Treatment

Advanced Healthcare Materials, EarlyView.
A hyaluronic acid/tannic acid‐engineered Prussian blue oxygen nanogenerator loaded with IR780 is developed to enhance melanoma phototherapy. By integrating tumor targeting, oxygen self‐supply, and dual‐mode glutathione depletion, the nanoplatform effectively overcomes hypoxia and antioxidant defenses, potentiating synergistic photothermal/photodynamic ...
Chai‐How Hsu, I‐Ju Liu, Hsiang‐Yun Chih, Tsai‐Ching Hsu, Ju‐An Liang, Chia‐Wei Kuo, Bor‐Show Tzang, Wen‐Hsuan Chiang   +7 more
wiley   +1 more source