Results 51 to 60 of about 1,616,124 (301)

Impact of COVID-19 on Opioid Prescribing, Consumption, Pain, and Outcomes after Surgery

Annals of Surgery Open
Objective:. The aim is to compare opioid prescription, consumption, and patient-reported and clinical outcomes after surgical discharge pre- versus post-COVID-19 pandemic. Background:.
Dorna Kheirabadi, MD, Vidhya Gunaseelan, MBA, MS, MHA, Yenling Lai, MSPH, MS, Chad M. Brummett, MD, Jennifer F. Waljee, MD, MPH, MS, Michael J. Englesbe, MD, Mark C. Bicket, MD, PhD   +6 more
doaj   +1 more source

Attitudes and knowledge about naloxone and overdose prevention among detained drug users in Ningbo, China

Substance Abuse Treatment, Prevention, and Policy, 2012
Background To date there has been limited research on both the prevalence of overdose and drug user knowledge about overdose prevention and response methods in China.
Liu Yu, Bartlett Nicholas, Li Longhui, Lv Xiuyi, Zhang Yahai, Zhou Wenhua   +5 more
doaj   +1 more source

Correlates of recent nonfatal overdose among people who inject drugs in West Virginia

Harm Reduction Journal, 2021
Aim Experiencing a nonfatal overdose (NFOD) is a significant risk factor for a subsequent nonfatal or fatal overdose. Overdose mortality rates in rural Appalachian states are some of the highest in the USA, but little is known about correlates of ...
N. Jia Ahmad, Sean T. Allen, Rebecca Hamilton White, Kristin E. Schneider, Allison O’Rourke, Michelle Perdue, Charles Babcock, Michael E. Kilkenny, Susan G. Sherman   +8 more
doaj   +1 more source

Ethical by Design: Engaging the Community to Co-design a Digital Health Ecosystem to Improve Overdose Prevention Efforts Among Highly Vulnerable People Who Use Drugs

Frontiers in Digital Health, 2022
IntroductionThe COVID-19 pandemic highlighted significant structural barriers that exacerbated health inequities among people at-risk for overdose. Digital health technologies have the potential to overcome some of these barriers; however, development of
Kasey R. Claborn, Kasey R. Claborn, Kasey R. Claborn, Suzannah Creech, Quanisha Whittfield, Ruben Parra-Cardona, Andrea Daugherty, Justin Benzer   +7 more
doaj   +1 more source

ZBTB18 Dysfunction Promotes Neuropathic Pain via CHD4‐based Epigenetic Disinhibition of CLIC1 Channels in Sensory Neurons

Advanced Science, EarlyView.
In this study, we identify a novel functional role of ZBTB18 in regulating trigeminal‐mediated neuropathic pain. Nerve injury reduces ZBTB18 in trigeminal ganglion neurons, impairing CHD4/NuRD recruitment and de‐repressing Clic1. Elevated CLIC1 enhances chloride channel activity and neuronal hyperexcitability, thereby driving pain.
Shoupeng Wang, Zitong Huang, Yu Tao, Yunmei Zhang, Yufang Sun, Dongsheng Jiang, Weiwei Lu, Fuhai Ji, Gang Chen, Min Xu, Yuan Zhang, Jin Tao   +11 more
wiley   +1 more source

AASLD practice guidance on drug, herbal, and dietary supplement–induced liver injury

, 2022
Hepatology, EarlyView.
Robert J. Fontana, Iris Liou, Adrian Reuben, Ayako Suzuki, M. Isabel Fiel, William Lee, Victor Navarro   +6 more
wiley   +1 more source

Preventing opioid overdoses in Europe:a critical assessment of known risk factors and preventative measures [PDF]

, 2012
This report is the outcome of a project into opioid overdoses. The remit was to focus on finding practical methods of overdose prevention. In order to fulfil this remit, a critical review of existing knowledge on overdose prevention was conducted.
Frisher, Martin, Crome, Ilana, Baldacchino, Alexander Mario, Bloor, Roger, Baldacchino, Alex, Baldacchino, Alexander Mario; id_orcid   +5 more
core  

Force‐Electric Nanotentacles of Tantalum Implant Accelerate Cellular Energy Metabolism/Crosstalk for Immunomodulation‐Vascularized Bone Integration

Advanced Science, EarlyView.
A biomimetic force‐electric nanotentacle‐enabled tantalum (Ta) implant with surface‐nanostructured LiTaO3 (n‐LiTaO3) was first developed via laser nanofabrication combined with Li+‐induced in situ reaction, enabling the transduction of ultrasound into bioelectrical cues.
Taixing Zhang, Ke Ma, Kangqing Zuo, Pandong Lin, Tailong Zhang, Rongliang Ding, Linbo Zhang, Aonan Li, Yinchuan Wang, Yanling Huang, Jichao Feng, Guiyong Xiao, Yupeng Lu, Bing Han, Zhiqiang Wang, Ningbo Li   +15 more
wiley   +1 more source

Community-Engaged Research Ethics Training (CERET): developing accessible and relevant research ethics training for community-based participatory research with people with lived and living experience using illicit drugs and harm reduction workers

Harm Reduction Journal, 2023
Background Community-based participatory research (CBPR) can directly involve non-academic community members in the research process. Existing resources for research ethics training can be inaccessible to team members without an academic background and ...
Jeffrey Morgan, Scott D. Neufeld, Heather Holroyd, Jean Ruiz, Tara Taylor, Seonaid Nolan, Stephanie Glegg   +6 more
doaj   +1 more source

Restoring Endothelial Mitochondrial Homeostasis With a Bioactive Nanoshield Promotes Vascular Regeneration on Cardiovascular Implants

Advanced Science, EarlyView.
A bioactive poly(citrate‐polyglycol‐procyanidin) (PCGP) nanoshield is developed for cardiovascular implants to restore endothelial mitochondrial homeostasis following vascular injury. By preserving mitochondrial integrity, re‐establishing metabolic balance, and activating PI3K/Akt/eNOS‐NO signaling, the PCGP interface promotes functional endothelial ...
Xiyu Liu, Wen Zhang, Lunxin Liu, Lan Gui, Yumei Qin, Xiaohui Yang, Longjian Zhang, Chaohua Wang, Jinpeng Hu, Gaoyang Guo, Qing Jiang, Jin Wang, Li Yang, Bo Zhang, Yunbing Wang   +14 more
wiley   +1 more source