Results 151 to 160 of about 1,435,507 (315)

One‐Step Microfluidic Manufactured Fucose‐Decorated Sweetosomes Choose the Time and the Road for Their Intracellular Journey to Cancer Treatment

Advanced Healthcare Materials, EarlyView.
Sweetosomes, a new class of fucose‐decorated liposomes, are developed via a one‐step microfluidic process without surface chemistry. This study elucidates their main caveolae‐mediated entry and distinct endosomal trafficking. These nanostructures demonstrate superior endosomal escape, organelle acidity modulation, and prolonged plasma persistence ...
Mattia Tiboni, Mariele Montanari, Shiva Khorshid, Michele Verboni, Andrea Duranti, Simone Lucarini, Daniele Lopez, Annalisa Aluigi, Gianluca Morganti, Michele Menotta, Giovanna Panza, Daniel J. Klionsky, Barbara Canonico, Luca Casettari   +13 more
wiley   +1 more source

The Role of MDM2 Amplification and Overexpression in Tumorigenesis.

Cold Spring Harbor Perspectives in Medicine, 2016
J. Oliner, A. Y. Saiki, S. Caenepeel
semanticscholar   +1 more source

The Prognostic Potential of PD-L1, PD-1, CD3, CD4, and CD8 Expression in Patients with Head and Neck Cancers Depending on HPV16 Infection. [PDF]

Cancers (Basel)
Mucha-Małecka A, Biesaga B, Amrogowicz N, Grela-Wojewoda A, Püsküllüoğlu M, Przewoźnik M, Pluta E, Patla A, Roszkowski K, Małecki K.   +9 more
europepmc   +1 more source

FGFR2B Overexpression [PDF]

, 2020
openaire   +1 more source

Extracellular Vesicles Modulation by an Adiponectin Receptor Agonist Provides Cardioprotection for Myocardial Ischemic Injury

Advanced Healthcare Materials, EarlyView.
This study demonstrates that ALY688, a drug mimicking the heart‐protective hormone adiponectin, reduces myocardial ischemia injury. ALY688 increases the production of extracellular vesicles, which carry protective cargo including adiponectin itself.
Jialing Tang, Wing Yan Chung, Serena M. Pulente, Yubin Lei, Khang Nguyen, Eddie Tam, Nadya M. Morrow, Ilka Lorenzen‐Schmidt, Fengxia Xiao, Augusto Zani, Dylan Burger, Hye Kyoung Sung, Erin E. Mulvihill, Gary Sweeney   +13 more
wiley   +1 more source

LINC01117 promotes the malignant proliferation of lung adenocarcinoma by increasing HOXD8 mRNA stability. [PDF]

Mol Med Rep
Zeng L, Shi J, Zhang C, Dong Y, Chen Y, Zhang Q, Zhang L, Yang S.   +7 more
europepmc   +1 more source

Photothermal‐Activated Antibacterial Amyloid‐Polyphenol‐Iron Hydrogels for Synergistic Wound Healing

Advanced Healthcare Materials, EarlyView.
We report a thermally triggered supramolecular hydrogel (LTFe) formed by Fe3+ and tannic acid on lysozyme amyloid fibrils. Fe3+ enables rapid gelation and photothermal transduction with an efficiency of 88.56%. The LTFe hydrogel exhibits excellent biocompatibility, potent antibacterial activity against E. coli and S.
Di Wu, Jiangtao Zhou, Yang Shen, Qiyao Sun, Tong Li, Xiaoyang Zou, Bin Liu, Hongshan Liang, Raffaele Mezzenga   +8 more
wiley   +1 more source

Overexpression of [delta]-Pyrroline-5-Carboxylate Synthetase Increases Proline Production and Confers Osmotolerance in Transgenic Plants

Plant Physiology, 1995
P. Kishor, Z. Hong, G. Miao, CAA. Hu, D. Verma   +4 more
semanticscholar   +1 more source

Impact of high-mobility-group A2 overexpression on epithelial-mesenchymal transition in pancreatic cancer

, 2019
Jian Gong,1 Yuxiang Wang,1 Buping Jiang,1 Bin Xu,1 Chuanzhen Hu2,31Department of Hepato-Biliary-Pancreatic Surgery, Shanghai Tenth People’s Hospital Affiliated to Tongji University, Shanghai 200072, People’s Republic of China; 2Department of ...
Hu C, Xu B, Jiang B, Gong J, Wang Y
core  

Correction: Platelet membrane-camouflaged nanoparticles carry microRNA inhibitor against myocardial ischaemia‒reperfusion injury. [PDF]

J Nanobiotechnology
Wang T, Zhou T, Xu M, Wang S, Wu A, Zhang M, Zhou YL, Shi J.   +7 more
europepmc   +1 more source